Abstracts tagged "psoriatic arthritis and randomized trials"

Abstract Number: L11 • 2018 ACR/ARHP Annual Meeting
Etanercept and Methotrexate As Monotherapy or in Combination in Patients with Psoriatic Arthritis: A Phase 3, Double-Blind, Randomized Controlled Study
Philip J. Mease¹, Dafna D. Gladman², David H. Collier³, Christopher T. Ritchlin⁴, Philip S. Helliwell⁵, Lyrica Liu⁶, Gregory J. Kricorian³ and James B. Chung³, ¹Swedish Medical Center and University of Washington, Seattle, WA, ²University of Toronto, Toronto, ON, Canada, ³Amgen Inc., Thousand Oaks, CA, ⁴University of Rochester Medical Center, Rochester, NY, ⁵University of Leeds, Leeds, United Kingdom, ⁶Amgen Inc., South San Francisco, CA
Background/Purpose: Methotrexate (MTX) and tumor necrosis factor inhibitors (TNFi) such as etanercept (ETN) are often prescribed for psoriatic arthritis (PsA) either alone or in combination,…
Abstract Number: 2559 • 2018 ACR/ARHP Annual Meeting
Efficacy and Safety of Ixekizumab in Patients with Active Psoriatic Arthritis and Previous Inadequate Response to TNF Inhibitors: Two-Year Follow-up from a Phase 3 Study
Ana-Maria Orbai¹, Amanda M. Gellett², Lisa Kerr² and Arnaud Constantin³, ¹Johns Hopkins University School of Medicine, Baltimore, MD, ²Eli Lilly and Company, Indianapolis, IN, ³Hopital Pierre-Paul Riquet, Toulouse, France
Background/Purpose: Ixekizumab (IXE), a high-affinity monoclonal antibody that selectively targets IL-17A, was superior to placebo (PBO) at Week (Wk) 24 for treating PsA signs and…