Abstracts tagged "proteomics and salivary hypofunction"

Abstract Number: 556 • ACR/ARHP Annual Meeting 2017
Identification and Validation of S100 Salivary Proteins As Putative Biomarkers for Different Subsets of Primary Sjögren’s Syndrome Patients
Chiara Baldini¹, Francesco Ferro², Nadia Ucciferri³, Enza Polizzi², Silvia Rocchiccioli³, Marta Mosca² and Antonella Cecchettini³, ¹Internal Medicine, Rheumatology Unit, University of Pisa, Pisa, Italy, ²Rheumatology Unit, University of Pisa, Pisa, Italy, ³IFC, CNR, Pisa, Italy
Background/Purpose: S100 A proteins are multifunctional proteins expressed predominantly by myeloid cells, with a regulatory role in a variety of cellular processes including inflammation. Recently,…
Abstract Number: 2797 • ACR/ARHP Annual Meeting 2015
Identification of Serum Biomarker for the Glandular Dysfunction of Primary Sjögren’s Syndrome
Ayumi Nishikawa¹, Katsuya Suzuki¹, Yoshiaki Kassai², Yuumi Gotou³, Takahiro Miyazaki⁴, Maiko Takiguchi⁴, Rimpei Morita⁵, Akihiko Yoshimura⁵ and Tsutomu Takeuchi¹, ¹Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, ²Takeda Pharmaceutical Company, Fujisawa, Japan, ³Inflammation Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Tokyo, Tokyo, Japan, ⁴Inflammation Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Ltd., Kanagawa, Japan, ⁵Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan
Background/Purpose: Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease characterized by dry eye and mouth. Measurements of un-stimulated salivary flow and Schirmer’s test are…