Proteoglycan Archives - ACR Meeting Abstracts

Abstract Number: 0799 • ACR Convergence 2025
Citrullination of neutrophil serine proteases enhances proteolytic activity, stability and autoantigenicity in Rheumatoid Arthritis
Mario Navarrete Lagos, Ramiza Zaman, Jun Kim, Jeba Atkia Maisha, Hani El-Gabalawy and Liam O'Neil, University of Manitoba, Winnipeg, MB, Canada
Background/Purpose: In Rheumatoid Arthritis (RA), autoantibodies develop against endogenous proteins containing the amino acid citrulline, which results from a post-translational modification of arginine catalyzed by…
Abstract Number: 1798 • ACR Convergence 2025
Proteomic Profiling of Chondrogenic Gene Therapy in Human MSCs Reveals Distinct Regenerative Pathways for Articular Cartilage Repair
Patricia Quaranta¹, Jagadeesh K Venkatesan², Valentina Calamia³, Patricia Fernández-Puente⁴, francisco J Blanco⁵, Magali Cucchiarini² and Cristina Ruiz-Romero⁶, ¹Instituto de Investigacion Biomedica de A Coruna (INIBIC), coruna, Spain, ²Center of Experimental Orthopaedics, Saarland University and Saarland University Medical Center, Homburg, Germany, ³INIBIC, A Coruña, Spain, ⁴Instituto de Investigacion Biomedica de A Coruna (INIBIC), coruña, Spain, ⁵INIBIC-University of A Coruña, A Coruña, Galicia, Spain, ⁶Department of Rheumatology, Rheumatology Research Group (GIR) Biomedical Re-search Institute (INIBIC),, A Coruña, Spain
Background/Purpose: Rheumatic diseases are characterized by pain and a progressive loss of joint function. Classical treatments alleviate pain symptoms but fail to fully repair sites…

Abstracts tagged "Proteoglycan"

Citrullination of neutrophil serine proteases enhances proteolytic activity, stability and autoantigenicity in Rheumatoid Arthritis

Proteomic Profiling of Chondrogenic Gene Therapy in Human MSCs Reveals Distinct Regenerative Pathways for Articular Cartilage Repair