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Abstracts tagged "prolactin and systemic lupus erythematosus (SLE)"

  • Abstract Number: 759 • ACR/ARHP Annual Meeting 2015

    Prolactin Level Is Independently Associated with Circulating CD4+CD28null in Systemic Lupus Erythematosus Patients

    Manuel Ugarte-Gil1,2, César Sánchez-Zúñiga3, Rocio V. Gamboa-Cardenas1, Madeley Aliaga-Zamudio3, Francisco Zevallos1, Giannina Tineo-Pozo3, Jorge M. Cucho-Venegas1, Ana Mosqueira-Riveros3, Risto Perich-Campos1,4, Jose Alfaro-Lozano1, Mariela Medina1, Zoila Rodriguez-Bellido1,4, Graciela S. Alarcon5 and Cesar A. Pastor-Asurza1,4, 1Rheumatology, Hospital Guillermo Almenara Irigoyen. EsSalud, Lima, Peru, 2Universidad Cientifica del Sur, Lima, Peru, 3Molecular Biology, Hospital Guillermo Almenara Irigoyen. EsSalud, Lima, Peru, 4Universidad Nacional Mayor de San Marcos, Lima, Peru, 5Medicine, University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Peripheral CD4+CD28null T-cells are a subset of long-lived cytotoxic CD4+ T-cells with pro-inflammatory functions, and they are increased in autoimmune and cardiovascular diseases. Prolactin…
  • Abstract Number: 1625 • ACR/ARHP Annual Meeting 2013

    Prolactin-Induced Interferon Regulatory Factor 1 Activation and Histone H4 Hyperacetylation In Monomac-6 Cells Correlating With Changes Seen In Monocytes From Systemic Lupus Erythematosus Patients

    Yiu Tak Leung1, Lihua Shi2, Kelly Maurer2, Li Song2, Michelle Petri3 and Kate Sullivan4, 1Medicine/Rheumatology, University of Pennsylvania, Philadelphia, PA, 2Immunology ARC 1216, The Children's Hospital of Philadelphia, Philadelphia, PA, 3Johns Hopkins University School of Medicine, Baltimore, MD, 4Allergy Immunology, The Children's Hospital of Philadelphia, Philadelphia, PA

    Background/Purpose: Epigenetic changes have been described in systemic lupus erythematosus (SLE) and offer a potential explanation for the chronicity of disease and missing heritability. Therapies…

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