ACR Meeting Abstracts

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Abstracts tagged "prevention"

  • Abstract Number: 2096 • ACR Convergence 2024

    A Model Based on Clinical and Molecular Data Predcits the Risk of Total Joint Replacement Progression in Knee OA Patients from the OAI

    Ignacio Rego-Perez1, Alejandro Duran-Sotuela2, Jorge Vazquez-Garcia2, Cristina Ruiz-Romero3, Valentina Calamia2, Carlota Fraga-Seijas4, Vanesa Balboa-Barreiro5, Sara Relaño2, María C. De Andrés2, Lucia Lourido2, Rocio Paz-Gonzalez2, Patricia Quaranta2, Patricia Fernández-Puente2, Nicola Veronese6, Natividad Oreiro7 and francisco J Blanco8, 1Instituto de Investigacion Biomedica de A Coruña-SERGAS, A Coruña, Spain, 2Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, A Coruña, Spain, 3INIBIC - CHUAC, A Coruña, Spain, 4INIBIC, A Coruña, Spain, 5Unidad de Epidemiología Clínica y Bioeostadística. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC)., A Coruña, Spain, 6Geriatric Unit, Department of Internal Medicine and Geriatrics, University of Palermo, Via del Vespro, 141, 90127, Palermo, Italy, A Coruña, Spain, 7CHUAC, La Coruna, Galicia, Spain, 8INIBIC-University of A Coruña, A Coruña, Spain

    Background/Purpose: There is a need to design models that predict the risk of total joint replacement (TJR) in patients with knee osteoarthritis (OA). Our aim…
  • Abstract Number: 0454 • ACR Convergence 2024

    Evaluating the Rate of Cervical Cancer Screening and HPV Vaccination in Women with Systemic Lupus Erythematosus Within a Large Urban Healthcare System

    Alana Haussmann1, Eunice Adu Dapaah2, John FitzGerald2 and Maureen McMahon3, 1University of California Los Angeles, Santa Monica, CA, 2UCLA, Los Angeles, CA, 3UCLA David Geffen School of Medicine, Los Angeles, CA

    Background/Purpose: Prior research has outlined an increased incidence of cervical dysplasia and cervical cancer in women diagnosed with systemic lupus erythematosus (SLE). These individuals face…
  • Abstract Number: 2285 • ACR Convergence 2024

    Safety and Tolerability of a Combination of Curcumin, Omega-3 and Vitamin-D: Results from the PASCOD Study, an RA Prevention Protocol

    Halle Cochrane, Caitlin Mcfadyen, Kale Mayor, Rhonda Silva, Kristin James, Xiaobo Meng, Dylan Mackay, Hani El-Gabalawy and Liam O'Neil, University of Manitoba, Winnipeg, MB, Canada

    Background/Purpose: Rheumatoid Arthritis (RA) is a progressive inflammatory autoimmune disease affecting 1% of the global population for which there is currently no cure. Recent research…
  • Abstract Number: 0535 • ACR Convergence 2024

    Oral Glucocorticoid Premedication Is at Least as Effective as Intravenous Glucocorticoid Premedication for Prevention of Infusion-related Reactions to Rituximab in Rheumatoid Arthritis Patients

    Pauline Bovens1, Luuk Van Esveld2, Maike Wientjes1, Noortje van Herwaarden3, David Ten Cate4, Eward Melis3, Nienke Lesuis5, Bart van den Bemt6 and Alfons den Broeder1, 1Sint Maartenskliniek, Ubbergen, Netherlands, 2Sint Maartenskliniek, Utrecht, Netherlands, 3Sint Maartenskliniek, Nijmegen, Netherlands, 4Sint Maartenskliniek, Rotterdam, Netherlands, 5Hospital Group Twente, Almelo, Netherlands, 6Sint Maartenskliniek / Radboudumc, Ubbergen, Netherlands

    Background/Purpose: It has been demonstrated that pretreatment with intravenous glucocorticoids can prevent infusion-related reactions (IRR) that may occur in RA patients receiving rituximab infusions [1].…
  • Abstract Number: 2414 • ACR Convergence 2024

    A Retrospective Comparative Analysis of Cardiovascular Risk Factors, Atherosclerotic Cardiovascular Disease and Statin Use as Secondary Prevention in a Cohort of Patients with Systemic Lupus Erythematosus versus Without Rheumatological Disease from a Single-Center Patient Registry

    Alma Aveytia Camacho1, Rakesh Gullapelli2, Vineetha Philip3, Soudabeh Daliri1, Ruba Memon4, Helene DiGregorio2, Lily Romero Karam2, Kanika Monga3, Eleonora Avenatti2, Khurram Nasir2 and Myriam Guevara1, 1Houston Methodist, Houston, TX, 2Houston Methodist Hospital, Houston, TX, 3Houston Methodist Hospital, Sugar Land, TX, 4Houston Methodist, Missouri City, TX

    Background/Purpose: Patients with systemic lupus erythematosus (SLE) have increased prevalence of cardiovascular risk factors (RFs), which predispose to higher risk of premature atherosclerotic cardiovascular disease…
  • Abstract Number: 0701 • ACR Convergence 2024

    Diagnostic Performances of Vascular Biomarkers Soluble Fms-like Tyrosine Kinase (sFlt-1) and Placental Growth Factor (PlGF) in Scleroderma Renal Crisis: A Case Control Study

    Aïcha Kante1, Paul Legendre2, Bérangère Joly3, bertrand Dunogue4, Alexandre Hertig5, Benjamin Terrier6, Elodie Massolin7, Felix Ackermann8, Luc Mouthon4, Jean Guibourdenche9 and Benjamin Chaigne10, 1Department of internal medicine, Centre de Compétence Maladies Rares autoimmunes et inflammatoires, Université Paris Cité, Paris, Ile-de-France, France, 2Service immunologie clinique, Centre hospitalier du Mans, Le Mans, France, Le Mans, 3Service d'Hématologie Biologique, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris (APHP.Nord), Université Paris Cité, Paris, Ile-de-France, France, 4Service de Médecine Interne, Centre de Référence Maladies Systémiques Autoimmunes et Autoinflammatoires Rares d'Ile de France de l’Est et de l’Ouest, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France, 5Department of Nephrology, Hôpital Foch, Suresnes, France, Suresnes, Ile-de-France, France, 6Service de Médecine interne, Hôpital Cochin, AP-HP, Paris, Ile-de-France, France, 7UF d'Hormonologie, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris (APHP), Paris, Paris, Ile-de-France, France, 8Department of Internal Medicine, Foch Hospital, Suresnes, France., Suresnes, France, 9APHP-CUP, Hôpital Cochin, F-75014 Paris, Université Paris Cité, Paris, Ile-de-France, France, 10Service de Médecine Interne, Centre de Référence Maladies Systémiques Autoimmunes et Autoinflammatoires Rares d'Ile de France de l’Est et de l’Ouest, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, Ile-de-France, France

    Background/Purpose: Scleroderma renal crisis (SRC) is a major vascular complication of systemic sclerosis (SSc), associated with high morbidity and mortality. Few biomarkers are available to predict…
  • Abstract Number: 2433 • ACR Convergence 2024

    Sequential Pneumococcal Vaccination in SLE: Immunogenicity, Side Effects and Comparison with PPSV23 Vaccination

    Rudrarpan Chatterjee1, Sai Yasaswini Kommaraju2, Shincy MR3 and Amita Aggarwal4, 1Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow., Lucknow, Uttar Pradesh, India, 2Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India, 3Central research lab, Kampewgowda Institute of Medical Sciences, Bengaluru, 4Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India, Lucknow, Uttar Pradesh, India

    Background/Purpose: SLE patients have increased risk of invasive pneumococcal disease due to immune dysregulation and drugs used in these patients. EULAR 2019 recommendation suggest sequential…
  • Abstract Number: 0844 • ACR Convergence 2024

    Effectiveness and Safety of the Recombinant Zoster Vaccine in Patients ≥18 Years of Age with Systemic Lupus Erythematosus or Multiple Sclerosis

    Sheryl Kluberg1, Sophie E. Mayer2, O’Mareen Spence3, Driss Oraichi4, Harry Seifert4, Omar Ali3, Huifeng Yun4, Andrew L. Simon5, Jenice S. Ko6, Caroline Hugh7, Meg Her7, Kathleen Shattuck7, Richard Platt8, Aziza Jamal-Allial9, Djeneba Audrey DJIBO10, Kimberly Daniels11, Qianli Ma12, Cheryl N McMahill-Walraven10, Rachel P. Ogilvie13, Kristin Palmsten14, Mano Selvan15, Najat Ziyadeh16, Alexis Ogdie17 and Michael George18, 1Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, 2Harvard Pilgrim Health Care Institute, Durham, 3GSK, Rockville, 4GSK, Rockville, MD, 5Harvard Pilgrim Healthcare Institute, Boston, MA, 6Harvard Pilgrim Health Care Ins􀆟tute, Boston, MA, 7Harvard Pilgrim Health Care Institute, Boston, MA, 8Harvard Pilgrim Health Care Institute / Harvard Medical School, Boston, MA, 9Carelon Research, Elevance Health, Newton, 10CVS Health, Blue Bell, 11Carelon Research, Elevance Health, Wilmington, 12Humana Healthcare Research, Inc., Louisville, 13Optum, Boston, MA, 14HealthPartners Institute, Minneapolis, 15Humana Healthcare Research, Sugar Land, Texas, 16Optum, Baltimore, MD, 17Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 18University of Pennsylvania, Philadelphia, PA

    Background/Purpose: The recombinant zoster vaccine (RZV) is US Food and Drug Administration-approved for the prevention of herpes zoster (HZ, shingles) in adults ≥50 years, and…
  • Abstract Number: 2588 • ACR Convergence 2024

    Examining the Influence of Socioeconomic Status on Osteoarthritis Prevalence and Risk Factors Among New York Residents

    Titilayo Adeniran1, David Cecil2 and Ahinee Amamoo3, 1Hospital for Special Surgery (HSS), New York, NY, 2Samford University, Birmingham, 3Samford University, Birmingham, AL

    Background/Purpose: Osteoarthritis (OA) is a chronic, progressive condition affecting the musculoskeletal system, significantly impacting the quality of life and mobility of millions worldwide. It is…
  • Abstract Number: 0138 • ACR Convergence 2024

    SARS-CoV-2 Vaccine Acceptance, Hesitancy and Uptake in a Cohort of Patients with Inflammatory Rheumatic Diseases (IRD)

    iulia roman1, Xenofon Baraliakos2, Uta Kiltz3, Juergen Braun4 and Ioana Andreica5, 1Rheumazentrum Ruhrgebiet, Herne, Germany, 2Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, 3Rheumazentrum Ruhrgebiet Herne, Ruhr-University, D-44649 Herne, Germany, 4Rheuma Praxis, Ruhr-University Bochum, Berlin, Germany, 5Rheumazentrum Ruhrgebiet Herne, Herne, Germany

    Background/Purpose: Vaccine acceptance is important to achieve high vaccination coverage and possibly herd immunity. Related to the evolution of the SARS-CoV-2 pandemic with its socio-political…
  • Abstract Number: 0995 • ACR Convergence 2024

    What Is the Carbon Footprint of Adalimumab Originator and Its Various Biosimilar Drugs?

    Ines Moninot1, ROLAND CHAPURLAT2, Elodie FEURER1, Pierre-Jean Cottinet3, Minh-Quyen Le3 and Aurélie Fontana1, 1Hospices Civils Lyon, Lyon, France, 2INSERM 1033, LYON, France, 3INSA Lyon, Lyon, France

    Background/Purpose: In developed countries, the impact of healthcare systems on the environment is sizeable (roughly 8% of the carbon footprint). So, it is essential to…
  • Abstract Number: 2612 • ACR Convergence 2024

    Two-Week Methotrexate Discontinuation in Autoimmune Rheumatic Diseases Patients Vaccinated with Recombinant Herpes Zoster Vaccine: An Interim Analysis of a Prospective Randomized Phase 4 Study

    Ana Cristina Medeiros-Ribeiro1, Joao de Oliveira2, Nadia Aikawa3, Sandra Pasoto2, Leonard Kupa2, Carla Goncalves Schahin Saad4, Luciana Parente2, ANA PAULA ASSAD2, Eduardo Borba2, Emily Figueiredo Neves Yuki2, Andrea Shimabuco4, Karina Bonfiglioli2, Diogo Domiciano2, Percival Sampaio-Barros4, Andre Franco2, Julio Moraes5, Murillo Dorio2, Claudia Goldenstein-Schainberg2, Henrique Carriço Da Silva2, Lucas Guimarães2, Fernanda Chaer6, Caio Laguna Reis de Carvalho2, Henrique Dalmolin2, Clovis Silva7 and Eloisa Bonfa2, 1Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Jose Dos Campos, Brazil, 2Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil, São Paulo, SP, Brazil, 3Rheumatology Division and Pediatric Rheumatology Unit, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil, 4Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, SP, Brazil, 5Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil, Jundiai, Brazil, 6Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Santos, Brazil, 7Rheumatology Division and Pediatric Rheumatology Unit, Instituto da Criança e do Adolescente, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, SP, Brazil

    Background/Purpose: Temporary methotrexate (MTX) discontinuation may enhance vaccine immune response, but there are no data for the recombinant zoster vaccine (RZV). This study assessed if…
  • Abstract Number: 0156 • ACR Convergence 2024

    Psoriasis and Psoriatic Arthritis Are Independent Risk Factors for Non-Fatal Cardiovascular Admissions in Transition-Age Young Adults

    Anurag Goel1, Joshua Tanzer2 and Vinit Gilvaz3, 1The Warren Alpert Medical School of Brown University, Providence, RI, 2Lifespan Biostatistics, Epidemiology, Research Design, and Informatics Core, Providence, RI, 3The Warren Alpert Medical School of Brown University, East Providence, RI

    Background/Purpose: Psoriasis (PsO) and psoriatic arthritis (PsA) are closely linked inflammatory conditions that can affect both children and adults. In children, these diseases are associated…
  • Abstract Number: 1066 • ACR Convergence 2024

    Development of a Pharmacy-Led Intervention to Improve Osteoporosis Screening in VA Community-Based Outpatient Clinics

    Krista Topalsky1, Lee Arphai2, Mary Ellen Amos2, Amanda Mertz2, Christopher Blum3, Timothy Godbey2, Lori Leonard2, Maya Mattar4, Elizabeth Cable2 and Robert Wenzell2, 1University Hospitals/ Case Western Reserve University, Shaker Heights, OH, 2Cleveland VA Medical Center, Cleveland, OH, 3Cleveland VA Medical Center, Cleveland, 4Louis Stokes VA medical Center, Mayfield Heights, OH

    Background/Purpose: Osteoporosis is a major public health concern in the United States, leading to significant morbidity, mortality, and increased economic burden. Fractures are projected to…
  • Abstract Number: 2672 • ACR Convergence 2024

    Prevention of the Development of Rheumatoid Arthritis by a 1-year Course of Methotrexate in ACPA-negative Arthralgia Patients at Increased Risk for Rheumatoid Arthritis: 4 Year Results of the TREAT EARLIER Trial

    Quirine Dumoulin1, Doortje Krijbolder2, Karen Visser3, Leroy Lard4 and Annette van der Helm-van Mil5, 1Leiden University Medical Centre, Leiden, Zuid-Holland, Netherlands, 2Leiden University Medical Centre, Leiden, Netherlands, 3Haga Hospital The Hague, Amsterdam, Netherlands, 4Haaglanden Medical Center The Hague, Leidschendam, Netherlands, 5LUMC, Leiden, Zuid-Holland, Netherlands

    Background/Purpose: Currently, prevention possibilities of developing ACPA-negative rheumatoid arthritis (RA) are unknown. Studying this is challenging because many ACPA-negative at-risk individuals have low risk of…
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