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Abstracts tagged "pregnancy"

  • Abstract Number: 1674 • ACR Convergence 2022

    In Utero Exposure to Hydroxychloroquine Does Not Associate with Ocular Toxicity as Assessed by Optical Coherence Tomography Five Years After Birth

    Peter Izmirly1, Mala Masson2, Michael Marmor3, Noel Zahr4, Nathalie Costedoat-Chalumeau5 and Jill Buyon1, 1NYU Grossman School of Medicine, New York, NY, 2NYU Langone Medical Center- Division of Rheumatology, New York, NY, 3Stanford University, Stanford, CA, 4Pitié-Salpêtrière Hospital, Paris, France, 5Inserm DR Paris 5, Paris, France

    Background/Purpose: The preventive approach to congenital heart block with hydroxychloroquine (HCQ) [PATCH] study supported the efficacy of HCQ to reduce the recurrence rate of cardiac…
  • Abstract Number: 0958 • ACR Convergence 2022

    Azathioprine Metabolite Levels and Outcomes During Pregnancies in Women with Rheumatic Disease

    Stephen Balevic1, Catherine Sims2, Amanda Eudy3 and Megan Clowse2, 1Duke Clinical Research Institute, Durham, NC, 2Duke University, Durham, NC, 3Duke University, Raleigh, NC

    Background/Purpose: Despite the wide use of AZA during pregnancy, there are no studies evaluating the impact of pregnancy on AZA metabolites 6-thioguanine nucleotide (6-TGN) and…
  • Abstract Number: 2022 • ACR Convergence 2022

    Outcome of Pregnancy in Women with Primary Sjögren’s Syndrome Compared to the General Population: The French Multicenter Prospective GR2 Study

    Gregoire Martin de Fremont1, Nathalie Costedoat-Chalumeau2, Rakiba Belkhir3, Gaelle Guettrot-Imbert4, Nathalie Morel4, Gaetane Nocturne5, Anna Molto6, Tiphaine Goulenok7, Elisabeth Diot8, Estibaliz Lazaro9, Laurent Perard10, Nicole Ferreira11, Maelle Le Besnerais12, Nicolas Limal7, Nihal Martis13, Noémie Abisror14, Odile Debouverie15, Christophe Richez16, Vincent Sobanski17, Francois Maurier18, Gaetan Sauvetre12, Herve Levesque12, Marie Agnes Timsit19, Nathalie Tieule13, Pauline Orquevaux20, GEFA Collaborative group21, Matthieu Mahevas22, Celine Lartigau Roussin23, Elodie Chauvet24, Emilie Berthoux25, Francoise Sarrot Reynauld26, Loic Raffray27, Marion Couderc28, Nicolas Martin Silva29, Noemie Jourde Chiche30, Nicolas Belhomme31, Thierry Thomas32, Vincent Poindron33, Viviane Queyrel13, Juliette Delforge34, Camille Le Ray35, Emmanuelle Pannier35, Xavier Mariette36, Veronique Le Guern4 and Raphaèle Seror37, 1Rheumatology department, Kremlin Bicêtre hospital, APHP, Paris, France, 2Inserm DR Paris 5, Paris, France, 3Rheumatology departement, Bicêtre, Paris-Saclay university, Le Kremlin Bicêtre, France, 4Hôpital Cochin, Paris, France, 5APHP, Le Kremlin Bicêtre, France, 6Rheumatology Department, Cochin Hospital, APHP, Paris, France, 7APHP, Paris, France, 8CHU Tours, Tours, France, 9Bordeaux Hospital University, Bordeaux, France, 10CHU Lyon, Lyon, France, 11department of Internal Medecine, CHU de Tours, Tours, France, 12CHU Rouen, Rouen, France, 13CHU Nice, Nice, France, 14Hopital Saint Antoine, Paris, France, 15CHU Poitiers, Poitiers, France, 16Université de Bordeaux, Bordeaux, France, 17Université de Lille, Lille, France, 18Hôpitaux privés de Metz, Metz, France, 19CHU Brest, Brest, France, 20CHU Reims, Reims, France, 21Saint Joseph Hospital, Marseille, France, 22CHU Mondor, Creteil, France, 23CH La Réunion, CH la Réunion, France, 24CH Cabestany, Cabestany, France, 25CH Saint Joseph Saint Luc, Lyon, France, 26CHU Grenoble, CHU Grenoble, France, 27CH St Denis Reunion, Saint Denis Reunion, France, 28University Hospital, Clermont-Ferrand, France, 29CHU Caen, Caen, France, 30APHM, Marseille, France, 31CHU Rennes, Rennes, France, 32CHU Saint Etienne, Saint Etienne, France, 33Immunologie clinique et médecine interne, Hôpitaux universitaires de Strasbourg, Strasbourg, France, 34Jean Verfier, Bobigny, France, 35Port Royal, Paris, France, 36Paris-Saclay University, Rueil Malmaison, Ile-de-France, France, 37University Hospital Paris-Saclay, Le Kremlin Bicêtre, France

    Background/Purpose: In the context of primary Sjögren's syndrome (pSS), only a few retrospective studies using heterogeneous methods have investigated the risk of adverse pregnancy outcomes…
  • Abstract Number: 1711 • ACR Convergence 2021

    Increasing Preeclampsia Knowledge in SLE with a Specific Educational Tool: Preliminary Results

    Joo Young (Esther) Lee1, Arielle Mendel2, Isabelle Malhamé2, Sasha Bernatsky1 and Evelyne Vinet3, 1McGill University, Montréal, QC, Canada, 2McGill University Health Centre, Montréal, QC, Canada, 3McGill University Health Centre, Mont Royal, QC, Canada

    Background/Purpose: Pregnant women with systemic lupus erythematosus (SLE) are at high risk of preeclampsia, leading to substantial maternal and fetal morbidity. Aspirin reduces preeclampsia risk…
  • Abstract Number: 1712 • ACR Convergence 2021

    Adverse Outcomes and Rehospitalization After Delivery Among Women with Systemic Lupus Erythematosus or Rheumatoid Arthritis and Their Infants

    Julianna Sabo1, Namrata Singh2, Deborah Crane1, David Doody3, Melissa Schiff4 and Beth Mueller5, 1University of Washington, Seattle, WA, 2University of Washington, Bellevue, WA, 3Fred Hutchinson Cancer Research Center, Seattle, WA, 4University of Washington, University of New Mexico, Seattle, WA, 5Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA

    Background/Purpose: Women with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) have greater risk of adverse obstetric and birth outcomes than women without these conditions.…
  • Abstract Number: 1713 • ACR Convergence 2021

    Risk of Serious Infections in Offspring Exposed in Utero to Ustekinumab or Vedolizumab

    Jonah Gorodensky1, Sasha Bernatsky1, Waqqas Afif1, Yvan St-Pierre2, Kristian Filion1 and Evelyne Vinet3, 1McGill University, Montréal, QC, Canada, 2Research Institute of the McGill University Health Centre, Montréal, QC, Canada, 3McGill University Health Centre, Mont Royal, QC, Canada

    Background/Purpose: Ustekinumab, an IL-12/23 inhibitor, is indicated in adult patients with inflammatory bowel disease (IBD), psoriasis (PsO), and psoriatic arthritis (PsA) and vedolizumab, an α4β7…
  • Abstract Number: 1716 • ACR Convergence 2021

    Teratogenic Medication Use Associated with Favorable Odds of Contraception Counseling in a Cohort of Women with Systemic Lupus Erythematosus at a Large Tertiary Academic Medical Center

    Shruti Chandramouli1, Carolina Alvarez2, R. Gina Silverstein3 and Saira Sheikh4, 1Department of Internal Medicine, Division of Rheumatology, Allergy & Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 2University of North Carolina at Chapel Hill, Chapel Hill, NC, 3Department of Obstetrics & Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 4University of North Carolina Thurston Arthritis Research Center, and Department of Medicine, Division of Rheumatology, Allergy and Immunology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC

    Background/Purpose: Systemic lupus erythematosus (SLE) primarily affects women of childbearing age, who have an increased risk of pregnancy complications such as preterm labor and preeclampsia,…
  • Abstract Number: 0023 • ACR Convergence 2021

    Investigating Temporal Changes in Pregnancy Among Women with Rheumatoid Arthritis and Healthy Women Using Co-expression Network Analysis

    Matthew Wright1, Dana Goin2, Mette Smed3, J Lee Nelson4, Nicholas Jewell5, Jorn Olsen6, Merete Hetland7, Vibeke Zoffmann3 and Damini Jawaheer8, 1UCSF Benioff Children's Hospital Oakland, Oakland, CA, 2University of California San Francisco, San Francisco, CA, 3Juliane Marie Center, Rigshospitalet, Copenhagen, Denmark, 4Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA, 5University of California Berkeley, Berkeley, CA, 6Aarhus University Hospital, Aarhus, Denmark, 7DANBIO and COPECARE, Centre for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark, 8UCSF Benioff Children's Hospital Oakland / University of California San Francisco, Oakland, CA

    Background/Purpose: Rheumatoid arthritis (RA), while still an incurable disease, can often improve naturally during pregnancy. The specific mechanism(s) underlying this pregnancy-induced improvement, however, are not…
  • Abstract Number: 1717 • ACR Convergence 2021

    One Year After the Publication of the American College of Rheumatology (ACR) Guidelines for Management of Reproductive Health in Rheumatic Diseases, Has Anything Changed? An Analysis of Rheumatology Practice at a Tertiary Care Medical Center

    Yixuan Zhou1 and Sobia Hassan2, 1Rush University Medical Center, Chicago, IL, 2RUSH University, Chicago, IL

    Background/Purpose: Successful pregnancies in patients with rheumatic disease are possible when they are well-monitored, adequately treated, and planned during periods of disease quiescence. Previously, a…
  • Abstract Number: 0070 • ACR Convergence 2021

    Pregnancy Outcomes of Antiphospholipid Antibody Positive Patients: Prospective Results from AntiPhospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking (APS ACTION) Clinical Database and Repository (“Registry”)

    Zeynep Belce Erton1, Ecem Sevim2, Guilherme Ramires de Jesus3, Ricard Cervera4, Lanlan Ji5, Vittorio Pengo6, Amaia Ugarte7, Danieli Andrade8, Laura Andreoli9, Tatsuya Atsumi10, Paul R Fortin11, Maria Gerosa12, Yu Zuo13, Michelle Petri14, Savino Sciascia15, Maria Tektonidou16, Maria Angeles Aguirre17, D. Ware Branch18, Doruk Erkan1 and on Behalf of APS ACTION1, 1Hospital for Special Surgery, New York, NY, 2Montefiore Medical Center - Wakefield Campus, Bronx, NY, 3Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil, 4Hospital Clinic Barcelona, Barcelona, Spain, 5Peking University First Hospital, Beijing, China (People's Republic), 6Padova University Hospital, Padova, Italy, 7Hospital Universitario Cruces, Barakaldo, Spain, 8Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 9University of Brescia, Brescia, Italy, 10Hokkaido University, Sapporo, Japan, 11CHU de Quebec - Universite Laval, Québec City, QC, Canada, 12University of Milan, Milan, Italy, 13University of Michigan, Ann Arbor, MI, 14Johns Hopkins University School of Medicine, Baltimore, MD, 15University of Turin, Turin, Italy, 16FORZAFORTE HELLAS LTD, Athens, Greece, 17IMIBIC/Reina Sofia Hospital/University of Córdoba, Córdoba, Spain, 18University of Utah, Salt Lake City, UT

    Background/Purpose: APS ACTION Registry was created to study the natural course of disease over 10 years in persistently antiphospholipid antibody (aPL) positive patients with or…
  • Abstract Number: 1719 • ACR Convergence 2021

    Pandemic-Associated Complications in Pregnant Women with Rheumatic Diseases

    Diana Johnson, Hiral Dave, Yunjun Luo and Christina Chambers, University of California San Diego, La Jolla, CA

    Background/Purpose: Pregnant women with rheumatic diseases may have been particularly vulnerable to the various consequences of the current pandemic, whether or not they were infected…
  • Abstract Number: 0079 • ACR Convergence 2021

    Association Between Preconception Complement Levels and Use of Hydroxychloroquine with Pregnancy Outcome in Patients with Primary Antiphospholipid Syndrome and Carriers of Antiphospholipid Antibodies: An International Multicenter Study

    Daniele Lini1, Cecilia Nalli2, Laura Andreoli3, Francesca Crisafulli1, Micaela Fredi1, Maria Grazia Lazzaroni1, Viktoria Bitsadze4, Antonia Calligaro5, Valentina Canti6, Roberto Caporali7, Francesco Carubbi8, Cecilia Chighizola9, Paola Conigliaro10, Fabrizio Conti11, Caterina De Carolis12, Teresa Del Ross5, Maria Favaro5, Maria Gerosa9, Annamaria Iuliano13, Jamilya Khizroeva4, Alexander Makatsariya4, Pier Luigi Meroni14, Marta Mosca15, Melissa Padovan16, Roberto Perricone10, Patrizia Rovere Querini6, Gian Domenico Sebastiani13, Chiara Tani17, Marta Tonello18, Simona Truglia11, Dina Zucchi15, Franco Franceschini1 and Angela Tincani19, 1Rheumatology and Clinical Immunology Unit, ASST Spedali Civili and University of Brescia, Brescia, Italy, 2ASST SPEDALI CIVILI DI BRESCIA, Brescia, Italy, 3University of Brescia, Brescia, Italy, 4Department of Obstetrics and Gynecology, I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russia, 5Rheumatology Unit, Department of Medicine, University of Padua, Padua, Italy, 6Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy, 7Policlinico S. Matteo University, Pavia, Italy, 8Department of Biotechnological and Applied Clinical Science, Rheumatology Unit, School of Medicine, University of L'Aquila, L'Aquila, Italy, 9University of Milan, Milan, Italy, 10Rheumatology, Allergology and Clinical Immunology, Department of "Medicina dei Sistemi", University of Rome Tor Vergata, Rome, Italy, 11Lupus Clinic, Reumatologia, Dipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari, Sapienza Università di Roma, Rome, Italy, 12Polymedical Center for Prevention of Recurrent Spontaneous Abortion, Rome, Italy, 13Rheumatology Unit, Azienda Ospedaliera San Camillo-Forlanini, Rome, Italy, 14Division of Rheumatology, ASST.G Pini, Department of Clinical Sciences and Community Health, University of Milan and Istituto Auxologico Italiano, Milan, Italy, 15Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy, 16Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria S. Anna, Ferrara, Italy, 17Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy, 18BSC, Rheumatology Unit, Department of Medicine, University of Padua, Padua, Italy, 19ASST Spedali Civili-University of Brescia, Gussago, Italy

    Background/Purpose: APS is a rare autoimmune disease characterized by thrombotic events and/or pregnancy morbidities in the presence of confirmed positivity for aPL. Complement was demonstrated…
  • Abstract Number: 1722 • ACR Convergence 2021

    Risk of Pre-eclampsia and Impact of Disease Activity and Anti-rheumatic Treatment in Women with Rheumatoid Arthritis, Axial Spondylarthritis, and Psoriatic Arthritis – A Collaborative Matched Cohort Study from Sweden and Denmark

    Anne Emilie Secher1, Karin Hellgren2, Bente Glintborg3, Ane Rom4, Merete Hetland5 and Fredrik Granath2, 1COPECARE, Centre for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark, Frederiksberg, Denmark, 2Clinical Epidemiology Division, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden, 3COPECARE, Centre for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark, Glostrup, Denmark, 4The Juliane Marie Centre, Rigshospitalet, Copenhagen, Denmark, Copenhagen, Denmark, 5DANBIO and COPECARE, Centre for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark

    Background/Purpose: Pre-eclampsia is a pregnancy-related syndrome with potentially fatal outcomes. In RA, high disease activity has been associated to adverse pregnancy outcomes such as preterm…
  • Abstract Number: 0236 • ACR Convergence 2021

    Maternal Attachment, Anxiety and Depressive Symptoms in Pregnant Women with Rheumatic Diseases

    Luis Gerardo Espinosa-Banuelos1, Diana Carolina Rubio Torres2, Maria Corral2, Cassandra Skinner Taylor2, Lorena Perez-Barbosa2, Luz Fernanda Gutierrez Leal2, Abraham Yair Lujano-Negrete3, Jesus Cardenas-de La Garza2 and Dionicio Galarza-Delgado2, 1Faculty of Medicine and University Hospital Dr. Jose Eleuterio Gonzalez, UANL, Monterrey, Mexico, 2Hospital Universitario "Dr Jose E. Gonzalez", Monterrey, Mexico, 3Hospital Universitario Dr. José Eleuterio González, Monterrey, Mexico

    Background/Purpose: Untreated perinatal anxiety symptomatology can be related to symptoms of anxiety and depression during the postpartum. The psychological bond created by the mother between…
  • Abstract Number: 1723 • ACR Convergence 2021

    Factors Associated with Postpartum Flare in Women with Lupus

    Anitha Ramu1, Maedeh Veyseh1, Brianna Lally2, Shudan Wang3 and Anna Broder4, 1Jacobi Medical Center/Albert Einstein College of Medicine, Bronx, NY, 2Albert Einstein College of Medicine, Bronx, NY, 3Albert Einstein College of Medicine/Montefiore Medical Center, New York, NY, 4Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY

    Background/Purpose: Several prior studies have assessed disease activity in the setting of pregnancy and have shown that certain factors such as thrombocytopenia, systemic lupus erythematosus…
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Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

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