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Abstracts tagged "pregnancy and vasculogenesis"

  • Abstract Number: 872 • ACR/ARHP Annual Meeting 2014

    Interferon-α and Angiogenic Dysregulation in Pregnant Lupus Patients Destined for Preeclampsia

    Danieli Andrade1, Mimi Kim2, Luz P. Blanco3, S. Ananth Karumanchi4, Gloria Koo5, Patricia M. Redecha6, Kyriakos A. Kirou1, Angela M. Alvarez7, Melissa J. Mulla7, Mary K. Crow8, Vikki Abrahams7, Mariana J. Kaplan3 and Jane E. Salmon9, 1Hospital for Special Surgery, New York, NY, 2Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, 3Systemic Autoimmunity Branch, Intramural Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 4Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 5Autoimmunity & Inflammation, Hospital for Special Surgery, New York, NY, 6Rheumatology Research, Hospital for Special Surgery, New York, NY, 7Yale School of Medicine, New Haven, CT, 8Department of Medicine, Hospital for Special Surgery, New York, NY, 9Rheumatology, Hospital for Special Surgery, New York, NY

    Background/Purpose: Pregnant patients with SLE are at increased risk of placental insufficiency and preeclampsia, disorders associated with angiogenic factor imbalance. IFN-α, a critical element in…

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