Abstracts tagged "pregnancy and vasculogenesis"

Abstract Number: 872 • 2014 ACR/ARHP Annual Meeting
Interferon-α and Angiogenic Dysregulation in Pregnant Lupus Patients Destined for Preeclampsia
Danieli Andrade¹, Mimi Kim², Luz P. Blanco³, S. Ananth Karumanchi⁴, Gloria Koo⁵, Patricia M. Redecha⁶, Kyriakos A. Kirou¹, Angela M. Alvarez⁷, Melissa J. Mulla⁷, Mary K. Crow⁸, Vikki Abrahams⁷, Mariana J. Kaplan³ and Jane E. Salmon⁹, ¹Hospital for Special Surgery, New York, NY, ²Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, ³Systemic Autoimmunity Branch, Intramural Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ⁴Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, ⁵Autoimmunity & Inflammation, Hospital for Special Surgery, New York, NY, ⁶Rheumatology Research, Hospital for Special Surgery, New York, NY, ⁷Yale School of Medicine, New Haven, CT, ⁸Department of Medicine, Hospital for Special Surgery, New York, NY, ⁹Rheumatology, Hospital for Special Surgery, New York, NY
Background/Purpose: Pregnant patients with SLE are at increased risk of placental insufficiency and preeclampsia, disorders associated with angiogenic factor imbalance. IFN-α, a critical element in…

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