Abstracts tagged "pregnancy"

Abstract Number: 0430 • ACR Convergence 2024
Clues from Early Gestational Mean Arterial Pressure in Predicting Preeclampsia Risk in Systemic Lupus Erythematosus (SLE)
Rashmi Dhital¹, Dilli Poudel² and Ukachi Emeruwa³, ¹UC San Diego, Brentwood, TN, ²Vanderbilt University, Nashville, TN, Brentwood, TN, ³UC San Diego, San Diego
Background/Purpose: Systemic Lupus Erythematosus (SLE) is a known risk factor for chronic hypertension (cHTN) as well as preeclampsia. While the role of cHTN is known,…
Abstract Number: 0448 • ACR Convergence 2024
A Pregnant Lupus Patient’s Journey: Single-Center Outcomes and Opportunities
Divya Singh¹, Maya Faison², Molly Leavitt³, Megan Clowse⁴ and Cuoghi Edens⁵, ¹University of Chicago, Chicago, IL, ²University of Chicago, Chapel Hill, NC, ³MacNeal Hospital/Loyola Medicine, Chicago, IL, ⁴Duke University, Chapel Hill, NC, ⁵Section of Pediatric Rheumatology, Section of Rheumatology, University of Chicago, Chicago, IL
Background/Purpose: Nearly half of systemic lupus erythematosus (SLE) patients will experience pregnancy complications. These complications include increased rates of prematurity, miscarriage, pre-eclampsia, and mortality. Maternal…
Abstract Number: 1535 • ACR Convergence 2024
Variations in Tacrolimus Whole Blood Concentrations During Pregnancy and Its Implications for Therapeutic Drug Monitoring: A Systematic Review and Meta-analysis
Reem Farhat¹, Arielle Mendel², Isabelle Malhamé², Ami Grunbaum³, Sasha Bernatsky⁴ and Evelyne Vinet², ¹McGill University, Montreal, QC, Canada, ²McGill University Health Centre, Montreal, QC, Canada, ³Research Institute of the McGill University Health Centre, Montréal, QC, Canada, ⁴Research Institute of the McGill University Health Centre, Montreal, QC, Canada
Background/Purpose: Tacrolimus is a pregnancy-compatible immunosuppressive increasingly used in systemic lupus erythematosus (SLE) pregnancies. Physiological changes throughout pregnancy impact tacrolimus pharmacokinetics, altering the drug’s whole…
Abstract Number: 0431 • ACR Convergence 2024
Reproductive Health in Women with Rheumatic Diseases: Knowledge and Behaviors
Abraham Yair Lujano-Negrete¹, Lorena Perez-Barbosa², Conrado Garcia³, CASSANDRA SKINNER TAYLOR⁴, Jose Hernandez Linas³, Adriana Lobato-Belmonte³, Yesenia Ambriz Murillo⁵, Alfonso Gastelum-Strozzi⁶, Amaranta Manrique de Lara⁷, Ana Rodriguez-Flores⁸, Jesus Cardenas-de la Garza⁹, Marco Maradiaga-Cecena¹⁰, Galilea Rodriguez Orozco¹¹, Anahí Carrazco Chapa¹¹, Dionicio Galarza-Delgado¹² and Ingris del Pilar Pelaez Ballestas³, and Grupo de estudio de salud reproductiva en enfermedades reumáticas autoinmunes en Mexico, ¹Hospital Universitario Jose Eleuterio Gonzalez, UANL, Internal Medicine, Monterrey, Mexico, Monterrey, Mexico, ²Hospital Universitario, UANL, Monterrey, Mexico, ³Hospital General de Mexico Dr. Eduardo Liceaga, Rheumatology, Mexico City, Mexico, Mexico, Mexico, ⁴HOSPITAL UNIVERSITARIO DR JOSE ELEUTERIO GONZALEZ, MONTERREY, Mexico, ⁵Hospital Regional de Morelia, Rheumatology, Morelia, Mexico, Morelia, Mexico, ⁶Instituto de Ciencias Aplicadas y Tecnología, UNAM, Mexico City, Mexico, Monterrey, Mexico, ⁷Hospital General de Mexico Dr. Eduardo Liceaga, Rheumatology, Mexico City, Mexico, Mexico City, Mexico, ⁸Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico, ⁹Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico, ¹⁰Hospital General de Culiacan, Rheumatology, Culiacan, Mexico, Culiacan, Sinaloa, Mexico, ¹¹Hospital Universitario Jose Eleuterio Gonzalez, UANL, Rheumatology, Monterrey, Mexico, Monterrey, Mexico, ¹²UANL Hospital Universitario, Monterrey, Nuevo León, Mexico
Background/Purpose: Autoimmune rheumatic diseases (ARDs) affect women during their childbearing years, often leading to pregnancy complications. Effective management of this population requires family planning and…
Abstract Number: 0451 • ACR Convergence 2024
Macrophages and Interferon Upregulation in Placentas from Patients with Systemic Lupus Erythematosus, Primary Sjögren’s Disease and Antiphospholipid Syndrome
Juan J. Fierro¹, Mirthe Schoots¹, Silvia Liefers¹, Berber Doornbos-van der Meer², Gilles Diercks¹, Hendrika Bootsma³, Jelmer R. Prins¹, Johanna Westra¹ and Karina de Leeuw⁴, ¹University Medical Center Groningen, University of Groningen, Groningen, Groningen, Netherlands, ²University Medical Center Groningen, University of Groningen, Groningen, Netherlands, ³Department of Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, Groningen, Netherlands, ⁴University Medical Center Groningen, Groningen, Groningen, Netherlands
Background/Purpose: SLE, primary Sjögren’s disease (pSjD) and APS are systemic rheumatic diseases (SRD) that mainly affect women of childbearing age and have been associated with…
Abstract Number: 1647 • ACR Convergence 2024
Improved Fertility in Women with Rheumatoid Arthritis and a Wish to Conceive When Treated According to a Treat-to-target Approach Aimed at Remission
Cornelia H. Quaack¹, Esther Röder¹, Hetty M. Wintjes¹, Anneke J. van Steensel-Boon¹, Annemarie G.M.G.J. Mulders², Laura C.J. Kranenburg-van Koppen¹ and radboud J.e.m. Dolhain¹, ¹Department of Rheumatology, Erasmus University Medical Center, Rotterdam, Netherlands, ²Department of Obstetrics and Gynaecology, Erasmus Medical Center, Rotterdam, Netherlands
Background/Purpose: Time to conception, known as time to pregnancy (TTP), is prolonged in women diagnosed with RA. High rates of infertility, defined as the inability…
Abstract Number: 0432 • ACR Convergence 2024
Disease Activity During Pregnancy in Patients with Rheumatoid Arthritis or Spondyloarthritis: Results from the Multicentre Prospective GR2 Study
Marion couderc¹, celine lambert², sabrina hamroun³, denis gallot⁴, Nathalie Costedoat-chalumeau⁵, Laure Gossec⁶, Gaëlle Guettrot-Imbert⁷, Veronique LE GUERN⁷, Christophe Richez⁸, MArtin Soubrier⁹ and Anna Molto¹⁰, ¹CHU de Clermont-Ferrand, Clermont-Ferrand, ²chu clermont ferrand, clermont ferrand, France, ³Rheumatology Department - Cochin Hospital, Paris, France, ⁴Department of Obstetrics, CHU Clermont-ferrand, Clermont-Ferrand, Auvergne, France, ⁵University Paris Cité, Paris, France, ⁶Sorbonne Université, Paris, France, ⁷Cochin Hospital, Paris, France, ⁸Université de Bordeaux, Bordeaux, France, ⁹Gabriel-Montpied Hospital, Clermont-ferrand, France, ¹⁰Groupe Hospitalier Cochin, AP-HP, Paris, France
Background/Purpose: Pregnancy may have a beneficial effect on disease activity in rheumatoid arthritis (RA) but the evidence is more conflicting in spondyloarthritis (SpA). The aim…
Abstract Number: 0453 • ACR Convergence 2024
Risk of Active Disease Determines the Expert Opinion Use of Biologics in Pregnancy, but Less in Breastfeeding, and in Men Planning a Family
Andrea Pluma¹, Linda Rüegg², Sabrina Hamroun³, Axel Finckh⁴, Yvette Meissner⁵ and Frauke Foerger⁶, ¹Vall d'Hebron University Hospital, Barcelona, Spain, ²Inselspital, Bern University Hospital, Bern, Switzerland, ³Cochin University Hospital, Paris, Ile-de-France, France, ⁴Geneva University Hospital, Geneva, Switzerland, ⁵Deutsches Rheuma-Forschungszentrum, Berlin, Germany, ⁶University hospital Bern /Inselspital Bern, Bern, Switzerland
Background/Purpose: Counselling patients with rheumatic and musculoskeletal diseases (RMD) in the phase of reproduction, pregnancy and breastfeeding is a challenging task. The potential risk of…
Abstract Number: 1702 • ACR Convergence 2024
Placental Developmental Defects in a Humanized-TLR8 Mouse Model of Spontaneous Anti-Phospholipid Antibody Induced Pregnancy Loss
Yunwei Xia¹, Naomi I. Maria², Zhengzi Yi³, Chirag Raparia⁴, Gayathri Konanur Gopikrishna¹, Weijia Zhang³ and Anne Davidson², ¹Feinstein Institutes for Medical Research, Manhasset, ²Feinstein Institutes for Medical Research, Manhasset, NY, ³Mt. Sinai School of Medicine, New York, NY, ⁴Donald and Barbara Zucker School of Medicine At Hofstra/Northwell, Shoreham, NY
Background/Purpose: Antiphospholipid antibodies (aPL) confer a high risk for adverse pregnancy outcomes, especially in women with SLE. aPLs can induce pro-inflammatory signaling via TLR8 receptors,…
Abstract Number: 0434 • ACR Convergence 2024
Pregnancy Outcomes of Biosimilars and Non-TNF Inhibitor Biologic Disease-Modifying Antirheumatic Drugs: A Scoping Review
Vienna Cheng¹, Neda Amiri², Vicki Cheng¹, Ursula Ellis³, Jacquelyn J. Cragg¹, Mark Harrison¹ and Mary A. De Vera¹, ¹University of British Columbia, Faculty of Pharmaceutical Sciences, Vancouver, BC, Canada, ²University of British Columbia, Faculty of Medicine, Vancouver, BC, Canada, ³University of British Columbia, Woodward Library, Vancouver, BC, Canada
Background/Purpose: Biosimilar and biologic (b) DMARDs have revolutionized rheumatic disease management in the recent decades. As these drugs become introduced, it is important to understand…
Abstract Number: 0455 • ACR Convergence 2024
Contraception Counseling for Patients with Rheumatic and Musculoskeletal Diseases (RMDs) at a Tertiary Care Rheumatology Clinic: A Quality Improvement Project
Ikwinder Preet Kaur¹, Gurjit Kaeley², Cristine Arcilla³, Ngun Par⁴ and Thway Myant⁵, ¹University of Florida College of Medicine, Jacksonville, FL, ²UF COM-J, Ponte Vedra Beach, FL, ³University of Florida Jacksonville, Jacksonville, FL, ⁴University of Florida Jacksonville Physicians Inc, Jacksonville, ⁵UF Jacksonville, Mia, FL
Background/Purpose: RMD patients are at increased risk of adverse pregnancy outcomes either from the active disease itself or the use of immunosuppressants incompatible with pregnancy.…
Abstract Number: 1770 • ACR Convergence 2024
Assessing S100A4 and Myofibroblast Phenotypes in the Pathogenesis of Cardiac and Cutaneous Neonatal Lupus
Nalani Sachan¹, Christina Firl², Philip Carlucci³, Nicola Fraser², Robert Clancy⁴ and Jill Buyon⁵, ¹NYU Grossman School of Medicine, New York, NY, ²NYU Langone Health, New York, NY, ³New York University School of Medicine, New York, NY, ⁴Columbia University Medical Center, New York, NY, ⁵New York University Grossman School of Medicine, New York, NY
Background/Purpose: Neonatal lupus (NL), driven by fetal exposure to maternal anti-SSA/Ro autoantibodies, typically results in permanent cardiac manifestations in utero and/or a transient rash postnatally.…
Abstract Number: 0436 • ACR Convergence 2024
Family Planning in Rheumatology: A Single Center Quality Improvement Project
Sara Heard, Elena Cravens, Jeanne Gosselin and Juvena Hitt, University of Vermont Medical Center, Burlington, VT
Background/Purpose: Pregnancy in patients with rheumatologic disease can lead to serious maternal and fetal complications. Multinational surveys have shown that medical providers often fail to…
Abstract Number: 0576 • ACR Convergence 2024
Less Than 15% Unfavourable Pregnancy Outcomes in Patients with Recent-onset Axial Spondyloarthritis: The Analysis of the 10 Years DESIR Cohort Follow-up
Madeleine FRANC¹, Anne Tournadre² and Anna Molto³, ¹Groupe Hospitalier Cochin, APHP, Paris, France, ²Service de Rhumatologie, centre hospitalier universitaire de Clermont-Ferrand, Université Clermont Auvergne, Clermont-Ferrand, France, ³Groupe Hospitalier Cochin, AP-HP, Paris, France
Background/Purpose: Only scarce data is available regarding pregnancy outcomes in early axSpA. The objective of this study was to determine (a) the factors associated with…
Abstract Number: 1869 • ACR Convergence 2024
Analysis of Short-Term Side Effects Following COVID-19 Vaccination in Pregnancies Complicated by Autoimmune Inflammatory Rheumatic Diseases
Shunya Kaneshita¹, Christina Chambers², Diana Johnson¹, Arthur Kavanaugh¹, Richard Garfein¹ and Gretchen Bandoli¹, ¹University of California San Diego, La Jolla, CA, ²University of California, San Diego, La Jolla, CA
Background/Purpose: Pregnant women are particularly at risk of severe Coronavirus disease 2019 (COVID-19) infection, which is why the Centers for Disease Control and Prevention (CDC)…

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