Abstracts tagged "pQTL"

Abstract Number: 0067 • ACR Convergence 2021
Mendelian Randomisation Analysis of Protein Quantitative Trait Loci with Ankylosing Spondylitis Reveals Causative Involvement of Key Effector Proteins and Pathways
Nicholas Harvey¹, Zhixiu Li², Jose Garrido-Mesa³, Jie Zheng⁴, Paul Wordsworth⁵, John Reveille⁶, Mario Falchi³, Niccolo Rossi³, Alessia Visconti³, David Evans⁷ and Matthew Brown³, ¹Molecular Genetics, London, United Kingdom, ²Queensland University of Technology, Brisbane, Australia, ³King's College London, London, United Kingdom, ⁴Bristol University, Bristol, United Kingdom, ⁵Oxford University, Oxford, United Kingdom, ⁶Division of Rheumatology, The University of Texas Health Science Center at Houston, Houston, TX, ⁷University of Queensland, Brisbane, Australia
Background/Purpose: Susceptibility to ankylosing spondylitis (AS) is known to be highly influenced by genetic factors, with heritability assessed in twins of >90%, with >115 genetic…

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Abstracts tagged "pQTL"

Mendelian Randomisation Analysis of Protein Quantitative Trait Loci with Ankylosing Spondylitis Reveals Causative Involvement of Key Effector Proteins and Pathways