ACR Meeting Abstracts

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Abstracts tagged "Polymyalgia Rheumatica (PMR)"

  • Abstract Number: 0466 • ACR Convergence 2021

    Subclinical Large Vessel Vasculitis in Polymyalgia Rheumatica

    Eugenio De Miguel1, Pierluigi Macchioni2, Edoardo Conticini3, Corrado Campochiaro4, Rositsa Karalilova5, Giulia Klinowski2, Paolo Falsetti3, Irene Monjo6, Alessandro Tomelleri7, Zguro Batalov5 and Alojzija Hocevar8, 1Hospital Universitario La Paz, Madrid, Spain, 2Department of Rheumatology, IRCCS-S.Maria Nuova, Reggio Emilia, Italy, 3Rheumatology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy, 4Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR). San Raffaele Scientific Institute, Milan. Italy, Milan, Italy, 5Medical University of Plovdiv, University Hospital Kaspela, Plovdiv, Bulgaria, 6Hospital La Paz - IdiPAZ, Madrid, Spain, 7Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR). San Raffaele Scientific Institute, Milan, Milan, Italy, 8UKC Ljubjana, Ljubjana, Slovenia

    Background/Purpose: Polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) are closely related diseases. PMR occurs in approximately 50 % of GCA patients1, however the frequency…
  • Abstract Number: 0505 • ACR Convergence 2021

    Risk of Venous and Arterial Thromboembolism in Patients with Giant Cell Arteritis And/or Polymyalgia Rheumatica: A Veterans Health Administration Population-Based Study in the United States

    Despina Michailidou1, Tianyu Zhang2, Pavlos Stamatis3 and Bernard Ng4, 1Division of Rheumatology, University of Washington, Seattle, WA, 2Department of Biostatistics, University of Washington, Seattle, WA, 3Lund University, Lund, Sweden, 4Rheumatology Section, VA Puget Sound HCS, University of Washington, Seattle, WA

    Background/Purpose: Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are two chronic systemic inflammatory diseases that primarily affect elderly women. Both diseases can be complicated…
  • Abstract Number: 0507 • ACR Convergence 2021

    Tocilizumab in Patients with New Onset Polymyalgia Rheumatica (PMR-SPARE) – a Phase 2/3 Randomized Controlled Trial

    Michael Bonelli1, Helga Radner1, Josef Smolen1, Martina Durechova1, Jutta Stieger2, Rusmir Husic3, Andreas Kerschbaumer1, Christian Dejaco4 and Daniel Aletaha5, 1Medical University of Vienna, Vienna, Austria, 22nd Department of Medicine, Hietzing Hospital, Vienna, Austria, 3Medical University of Graz, Graz, Austria, 4Rheumatology, Hospital of Brunico (SABES-ASDAA), Brunico, Italy, Brunico, Italy, 5Medical University Vienna, Vienna, Austria

    Background/Purpose: PMR is the second most common inflammatory rheumatic disease of people aged 50 years or older. Glucocorticoid therapy is highly effective, but many patients…
  • Abstract Number: 0653 • ACR Convergence 2021

    Adherence to the 2015 ACR Guidelines for the Management of Polymyalgia Rheumatica and Screening for Osteoporosis at a Tertiary Care Medical Center

    Padmini Parameswaran1 and Michael Lucke2, 1Allegheny Health Network Medical Education Consortium, Pittsburgh, PA, 2Allegheny Health Network, Pittsburgh, PA

    Background/Purpose: Since the first description of polymyalgia rheumatica (PMR) in the early 1950s, the ideal dose and duration of glucocorticoid therapy has varied. In 2015,…
  • Abstract Number: 0952 • ACR Convergence 2021

    Outcomes of COVID-19 Infection in Patients with Primary Systemic Vasculitis and Polymyalgia Rheumatica: Results from the COVID-19 Global Rheumatology Alliance Physician Registry

    Sebastian Sattui1, Richard Conway2, Michael Putman3, Andrea Seet4, Kaley Beins5, Catherine Hill6, David Liew7, Sarah Mackie8, Puja Mehta9, Lorna Neill10, Gimena Gomez11, Maria Salinas12, Federico Maldonado13, Henrique Moriz14, Samia Studart15, NAFICE ARAUJO16, Ann Knight17, Davide Rozza18, Luca Quartuccio19, Maxime Samson20, Stephane Bally21, Alexandre Maria22, Pascal Chazerain23, Rebecca Hasseli24, Ulf Müller-Ladner25, Bimba Franziska Hoyer26, Reinhard Voll27, Rita Pinheiro Torres28, Mariana Luis29, Sandra Lúcia Ribeiro30, Samar Al Emadi31, Jeffrey Sparks32, Tiffany Hsu33, Kristin D'Silva34, Naomi Patel34, Leanna Wise35, Emily Gilbert36, Maria Valenzuela-Almada37, Ali Duarte-Garcia38, Manuel Ugarte-Gil39, Emily Sirotich40, Jean Liew41, Jonathan Hausmann42, Paul Sufka43, Suleman Bhana44, Rebecca Grainger45, Wendy Costello46, Lindsay Jacobsohn47, Zara Izadi4, Anja Strangfeld48, Elsa Frazão Mateus49, Kimme Hyrich50, Laure Gossec51, Loreto Carmona52, Saskia Lawson-Tovey50, Lianne Kearsley-Fleet53, Martin Schaefer54, Milena Gianfrancesco4, Pedro Machado55, Zachary Wallace34, Jinoos Yazdany4 and Philip Robinson56, 1Hospital for Special Surgery, New York, NY, 2St. James's University Hospital, Dublin, Ireland, 3Medical College of Wisconsin, Brookfield, WI, 4University of California San Francisco, San Francisco, CA, 5Vasculitis Foundation, Kansas City, MO, 6Queen Elizabeth Hospital, Woodville, Australia, 7Austin Health, Heidelberg, Australia, 8School of Medicine, University of Leeds, Leeds, United Kingdom, 9University College London, London, United Kingdom, 10PMR GCA Scotland, Perth, United Kingdom, 11Research Unit Argentine Society of Rheumatology, Buenos Aires, Argentina, 12Hospital Privado Universitario de Córdoba, Cordoba, Argentina, 13Sanatorio Güemes, Buenos Aires, Argentina, 14Hospital das Clinicas, Universidade Federal de Pernambuco, Pernambuco, Brazil, 15HOSPITAL GERAL DE FORTALEZA, Fortaleza, Brazil, 16Instituto de ASsistencia Medica ao Servidor Publico Estadual de São Paulo, São Paulo, Brazil, 17Rheumatology, Institute of Medical Sciences, Uppsala University, Uppsala, Sweden, 18Epidemiology Research Unit, Italian Society of Rheumatology, Rome, Italy, 19Clinical Rheumatology, Department of Medicine, University of Udine, Udine, Italy, 20CHU Dijon Bourgogne, Hpital Franois Mitterrand, Dijon, Dijon, France, 21Nephrology and Dialysis Service, Metropole Savoie Hospital Center, Chambery, France, 22Department of Internal Medicine and Multiorganic Diseases, Saint-Eloi University Hospital of Montpellier, Montpellier, France, 23Department of Rheumatology and Internal Medicine, Diaconesses Croix Saint Simon Hospital, Paris, France, 24Department of Rheumatology and Clinical Immunology, Campus Kerckhoff, Justus Liebig University Giessen, Bad Nauheim, Germany., Bad Nauheim, Germany, 25JLU Giessen, Campus Kerckhoff, Dept. Rheum & Clin Immunol, Bad Nauheim, Germany, 26Universittsklinikum Schleswig-Holstein, Kiel, Germany, 27Department of Rheumatology and Clinical Immunology, University Medical Center, Faculty of Medicine, Albert-Ludwigs-University of Freiburg, Freiburg, Germany, 28Rheumatology Service, Egas Moniz Hospital, Lisboa Occidental Hospital Centre, Lisbon, Portugal, 29Department of Rheumatology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portuga, Coimbra, Portugal, 30Universidade Federal do Amazonas, Amazonas, Brazil, 31Hamad medical corporation, Doha, Qatar, 32Brigham and Women's Hospital, Boston, MA, 33Brigham and Women's Hospital, Jamaica Plain, MA, 34Massachusetts General Hospital, Boston, MA, 35LAC+USC/Keck Medicine of USC, Pasadena, CA, 36Mayo Clinic, Jacksonville, FL, 37Division of Rheumatology, Mayo Clinic, Rochester, MN, 38Mayo Clinic, Rochester, MN, 39Hospital Guillermo Almenara Irigoyen, Essalud/Universidad Científica del Sur, Lima, Peru, 40McMaster University, Hamilton, ON, Canada, 41Boston University, Boston, MA, 42Boston Children's Hospital / Beth Israel Deaconess Medical Center, Cambridge, MA, 43HealthPartners, Eagan, MN, 44Crystal Run Health, Montvale, NJ, 45University of Otago, Wellington, New Zealand, 46Irish Children's Arthritis Network, Bansha, Ireland, 47University of California San Francisco, Antioch, CA, 48Deutsches Rheuma-Forschungszentrum Berlin, Berlin, Germany, 49Liga Portuguesa Contra as Doenças Reumáticas (LPCDR), Lisbon, Portugal, 50University of Manchester, Manchester, United Kingdom, 51Sorbonne Université and Hôpital Pitié-Salpêtrière, Paris, France, 52Instituto de Salud Musculoesqueltica (InMusc), Madrid, Spain, 53Centre for Musculoskeletal Research, University of Manchester, Manchester, United Kingdom, 54German Rheumatism Research Center, Berlin, Germany, 55Centre for Rheumatology & Department of Neuromuscular Diseases, University College London, London, United Kingdom, 56University of Queensland School of Clinical Medicine, Brisbane, Queensland, Australia, Herston, Australia

    Background/Purpose: Patients with primary systemic vasculitis (PSV) and polymyalgia rheumatica (PMR) may be at high risk for poor COVID-19 outcomes due to the treatments used,…
  • Abstract Number: 1091 • ACR Convergence 2021

    Serum Metabolomic Profiling Identifies Potential Biomarkers in Arthritis in the Elderly

    Martha Cedeno1, Jessica Murillo Saich1, Roxana Coras2, Anahy Maria Brandy-Garcia3, Agueda Prior-Español4, Lourdes Mateo5, Melania Martinez-Morillo5 and Monica Guma6, 1University of California San Diego, La Jolla, CA, 2University of California San Diego/Department of Medicine, Autonomous University of Barcelona, San Diego, CA, 3Hospital Germans Trias i Pujol, Badalona, Spain, 4Department of Rheumatology, Germans Trias i Pujol. University Hospital, Badalona, Spain, 5Department of Rheumatology, Germans Trias i Pujol. University Hospital, Barcelona, Spain, 6University of California San Diego/San Diego VA Healthcare Service/Department of Medicine, Autonomous University of Barcelona, La Jolla, CA

    Background/Purpose: Elderly-onset RA (EORA) and polymyalgia rheumatica (PMR) are common rheumatic diseases in the elderly, but their pathogenesis is not yet fully understood. Seronegative EORAneg…
  • Abstract Number: 1392 • ACR Convergence 2021

    Assessment of a Patient Self-Report Frailty Tool in Patients with Polymyalgia Rheumatica

    Sebastian Sattui, Deanna Jannat-Khah, Lindsay Lally, Sarah Lieber, Lisa Mandl and Robert Spiera, Hospital for Special Surgery, New York, NY

    Background/Purpose: Frailty, a syndrome characterized by decreased physiologic reserve, is associated with chronic inflammation. We have shown a high prevalence of frailty in patients with…
  • Abstract Number: 1405 • ACR Convergence 2021

    Effectiveness of Tocilizumab in Cranial and Extracranial Phenotypes of Giant Cell Arteritis: Multicenter Study of 471 Cases

    Lara Sánchez-Bilbao1, Javier Loricera1, Santos Castañeda2, Clara Moriano3, Javier Narvaez4, Vicente Aldasoro5, Olga Maíz6, Rafael Melero7, Juan Ignacio Villa8, Paloma Vela9, Susana Romero-Yuste10, José Luis Callejas11, Eugenio De Miguel12, Eva Galindez-Agirregoikoa13, Francisca Sivera14, Jesús Carlos Fernández-López15, Carles Galisteo16, Iván Ferraz-Amaro17, Juan Carlos Nieto18, Juan Ramón de Dios19, Julio Sánchez20, Esther Fernández21, Isabel de la Morena22, Patricia Moya23, Roser Solans-Laqué24, Jose Luis Andreu25, Marcelino Revenga26, Eztizen Labrador27, Andrea García-Valle28, Adela Gallego29, Carlota Iñíguez30, Cristina Hidalgo31, Noemí Garrido-Puñal32, Ruth López-González33, José Andrés Román-Ivorra34, Sara Manrique Arija35, Paz Collado36, Enrique Raya11, Francisco Navarro37, Antoni Juan Mas38, Carmen Ordas39, Maria Dolors Boquet40, Noelia Álvarez-Rivas41, Maria Luisa Velloso-Feijoo42, Cristina Campos-Fernández43, Íñigo Rúa-Figueroa44, Arantxa Conesa45, Eva Salgado46, Miguel Ángel gonzalez-Gay47 and Ricardo Blanco48, 1Hospital Universitario Marqués de Valdecilla, Santander, Spain, 2Hospital Universitario de la Princesa, Madrid, Spain, 3Hospital Universitario de León, León, Spain, 4Division of Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, 5Complejo Hospitalario de Navarra, Pamplona, Spain, 6Hospital Universitario de Donostia, San Sebastián, Spain, 7Complexo Hospitalario Universitario de Vigo, Vigo, Galicia, Spain, 8Hospital Sierrallana, Torrelavega, Spain, 9Hospital General Universitario de Alicante, Alicante, Spain, 10Complejo Hospitalario Universitario de Pontevedra, Pontevedra, Spain, 11Hospital San Cecilio, Granada, Spain, 12Hospital Universitario La Paz, Madrid, Spain, 13Hospital Universitario de Basurto, Bilbao, Spain, 14Hospital Universitario de Elda, Alicante, Spain, 15Hospital Universitario Juan Canalejo, A Coruña, Spain, 16Hospital Universitari Parc Tauli, Saadell, Spain, 17Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain, 18Hospital General Universitario Gregorio Marañón, Madrid, Spain, 19Hospital Universitario de Araba, Mondragón, Spain, 20Hospital Universitario 12 de Octubre, Madrid, Spain, 21Hospital Clínico Universitario Virgen de la Arrixaca, Murcia, Spain, 22Hospital Clínico Universitario de Valencia, Valencia, Spain, 23Hospital Sant Pau, Barcelona, Spain, 24Hospital Vall d'Hebron, Barcelona, Spain, 25Hospital Universitario Puerta de Hierro, Madrid, Spain, 26Hospital Universitario Ramón y Cajal, Madrid, Spain, 27Hospital San Pedro, Logroño, La Rioja, Spain, 28Complejo Asistencial Universitario de Palencia, Palencia. Spain, Palencia, Spain, 29Complejo Hospitalario Universitario de Badajoz, Badajoz, Spain, 30Hospital Universitario Lucus Augusti, Lugo, Galicia, Spain, 31Hospital Universitario Salamanca, Salamanca, Spain, 32Hospital Universitario Virgen del Rocío, Sevilla, Spain, 33Complejo Hospitalario de Zamora, Zamora, Spain, 34Hospital Universitario y Politécnico La Fe, Valencia, Spain, 35Hospital Regional de Málaga, Málaga. Spain., Malaga, Spain, 36Hospital Universitario Severo Ochoa, Madrid, Spain, 37Hospital General Universitario de Elche, Elche, Spain, 38Hospital Universitario Son Llàtzer, Palma de Mallorca, Spain, 39Hospital de Cabueñes, Gijón, Spain, 40Hospital Arnau de Vilanova, Lleida. Spain., Lleida, Spain, 41Hospital San Agustín, Aviles, Spain, 42Hospital Universitario de Valme, Sevilla, Spain, 43Consorci Hospital General Universitari de Valencia, Valencia, Spain, 44Hospital Universitario Doctor Negrín, Gran Canaria, Spain, 45Hospital Universitario de Castellón, Castellón, Spain, 46Complejo Hospitalario Universitario de Ourense, Ourense, Spain, 47Research group on Genetic Epidemiology and Atherosclerosis in Systemic Diseases and in Metabolic Bone Diseases of the Musculoskeletal System, IDIVAL, Division of Rheumatology, Hospital Universitario Marqués de Valdecilla; School of Medicine, Universidad de Cantabria, Santander, Spain. Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa, 48Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain

    Background/Purpose: Giant cell arteritis (GCA) may be divided into cranial, and extracranial GCA phenotypes. Tocilizumab (TCZ) has shown efficacy and safety in GCA.Our aim was…
  • Abstract Number: 1407 • ACR Convergence 2021

    Characterization of Synovial Fluid T Cells in Polymyalgia Rheumatica: Implication of Th1 and Tc1 Effector Memory Profiles

    Rosanne Reitsema1, Lieske Wekema2, Wayel Abdulahad1, Peter Heeringa3, Minke Huitema1, Maria Sandovici3, Annemieke Boots3, Elisabeth Brouwer3 and Kornelis van der Geest3, 1Department of Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, 2Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, 3University Medical Center Groningen, Groningen, Netherlands

    Background/Purpose: Polymyalgia Rheumatica (PMR) is a common rheumatic inflammatory disease in the elderly. PMR is characterized by synovial inflammation of (peri)articular structures in the shoulders…
  • Abstract Number: 1416 • ACR Convergence 2021

    Dysregulated Glucose Metabolism and Dyslipidemia in GCA and PMR Patients at Diagnosis

    Idil Esen1, Philip Therkildsen2, Berit Dalsgaard Nielsen2, Anna van 't Ende1, Annemieke Boots1, Peter Heeringa1, Ellen-Margrethe Hauge2, Elisabeth Brouwer1 and Yannick van Sleen3, 1University Medical Center Groningen, Groningen, Netherlands, 2Aarhus University Hospital, Aarhus, Denmark, 3University of Groningen, Groningen, Netherlands

    Background/Purpose: Giant cell arteritis (GCA) is the large and medium vasculitis that affects elderly people GCA frequently overlaps with polymyalgia rheumatica (PMR). PMR is a…
  • Abstract Number: 1418 • ACR Convergence 2021

    Patient Reported Outcomes on Quality of Life in Patients with Giant Cell Arteritis and Polymyalgia Rheumatica

    Yannick van Sleen1, Kornelis van der Geest2, Annemieke Boots2, Maria Sandovici2 and Elisabeth Brouwer2, 1University of Groningen, Groningen, Netherlands, 2University Medical Center Groningen, Groningen, Netherlands

    Background/Purpose: Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are often overlapping inflammatory diseases that occur in people older than 50 years. Both diseases can…
  • Abstract Number: 0794 • ACR Convergence 2020

    Peripheral Blood T and B Lymphocyte Subsets in Arthritis in the Elderly

    Aina Teniente-Serra1, Lourdes Mateo2, Agueda Prior3, Monica Guma4, Eva Martinez-Caceres1 and Melania Martinez-Morillo5, 1Department of Immunology, Germans Trias i Pujol. University Hospital, Badalona, Badalona, 2Department of Rheumatology, Germans Trias i Pujol. University Hospital, Badalona, Badalona, 3Department of Rheumatology, Hospital Germans Trias i Pujol, Badalona, Spain, 4Division of Rheumatology, University of California San Diego, Department of Medicine, Autonomous University of Barcelona, La Jolla, CA, 5Hospital Germans Trias i Pujol, Barcelona, Spain

    Background/Purpose: Multiple lymphocyte subsets like T and B cells have been connected to joint infiltration and inflammation in rheumatoid arthritis (RA). Identification of leucocyte subsets…
  • Abstract Number: 1580 • ACR Convergence 2020

    Generalized Immune Activation in Structures Related to PMR or GCA on PET/CT Assessment Does Not Occur in Immune Checkpoint Inhibitor-Treated Patients Who Do Not Go on to Develop Rheumatic Immune-Related Adverse Events

    David Liew1, Aurora Poon2, Christopher McMaster3, Claire Owen4, Jessica Leung5, Albert Frauman2, Jonathan Cebon6, Andrew Scott6 and Russell Buchanan7, 1Austin Health, Melbourne, Victoria, Australia, Heidelberg, Victoria, Australia, 2Austin Health, Melbourne, Victoria, Australia, Melbourne, Victoria, Australia, 3Austin Health, Melbourne, Victoria, Australia, Pascoe Vale South, Victoria, Australia, 4Austin Health, Melbourne, Victoria, Australia, Ashburton, Victoria, Australia, 5Austin Health, Melbourne, Victoria, Australia, Melbourne, 6Austin Health, Melbourne, Victoria, Australia, Melbourne, Australia, 7Austin Health, Melbourne, Victoria, Australia, Heidelberg, Melbourne, Victoria, Australia

    Background/Purpose: The pathogenesis of rheumatic immune-related adverse events (irAEs) from checkpoint inhibitor cancer immunotherapy directed against programmed cell death protein 1 (PD-1) and programmed death…
  • Abstract Number: 1934 • ACR Convergence 2020

    What Is the Significance of Periarterial Temporal Small Vessel Inflammation (SVI) on Temporal Artery Biopsy (TAB) in the Diagnosis of Vasculitis? A Systematic Review and Meta-analysis

    Elise Belilos1, Steven Carsons2 and Sonya Mehta1, 1NYU Winthrop Hospital, Mineola, NY, 2NYU Long Island School of Medicine, Mineola, NY

    Background/Purpose: Isolated inflammation of small vessels including capillaries, venules and arterioles surrounding a normal temporal artery (SVI) in patients suspected of having giant cell arteritis…
  • Abstract Number: 0131 • ACR Convergence 2020

    Analysis of the Total Body Composition in a Cohort of Patients with Elderly Onset Arthritis

    Anahy María Brandy García1, Melania Martinez-Morillo2, Agueda Prior3, Rosa Serrano1, Lourdes Mateo4, Monica Guma5 and Laia Gifre2, 1Hospital Germans Trias i Pujol, Badalona, Spain, 2Hospital Germans Trias i Pujol, Barcelona, Spain, 3Department of Rheumatology, Hospital Germans Trias i Pujol, Badalona, Spain, 4Department of Rheumatology, Germans Trias i Pujol. University Hospital, Badalona, Badalona, 5University of California San Diego, La Jolla, CA

    Background/Purpose: Inflammatory arthritis in the elderly leads to greater comorbidity than that of the young patients, however, there are few data on body composition in…
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