ACR Meeting Abstracts

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Abstracts tagged "Polymyalgia Rheumatica (PMR)"

  • Abstract Number: 0746 • ACR Convergence 2025

    Impact of Frailty on Mortality in GCA and PMR: A Retrospective Cohort

    Fatima Hassan1, Michael Putman2 and Sebastian E Sattui3, 1Medical College of Wisconsin, Menomonee Falls, WI, 2The Medical College of Wisconsin, Milwaukee, WI, 3Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA

    Background/Purpose: Frailty, a syndrome associated with decreased physiologic reserve, is associated with adverse outcomes. The prevalence and impact of baseline frailty on the risk of…
  • Abstract Number: 1629 • ACR Convergence 2025

    Real-World Effectiveness of Interleukin-6 Receptor Inhibitors Compared to Methotrexate in Steroid-Refractory Frail Patients with Polymyalgia Rheumatica

    Sebastian E Sattui1, Christian Dejaco2, Kerri Ford3, Stefano Fiore4, Sebastian H Unizony5, Fenglong Xie6 and Jeffrey Curtis7, 1Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 2Medical University of Graz, Department of Rheumatology, Graz, Austria; Department of Rheumatology, Hospital of Brunico (SABES-ASDAA), Brunico, Italy, 3Sanofi, Cambridge, MA, 4Sanofi, Morristown, NJ, 5Massachusetts General Hospital, Harvard Medical School, Boston, MA, 6The University of Alabama at Birmingham, Birmingham, AL, 7Foundation for Advancing Science, Technology, Education and Research, Birmingham, AL

    Background/Purpose: A previous post hoc analysis of frail (defined by claims-based frailty index [CFI] ≥0.2) patients with PMR on second line (2L) and 3L treatment…
  • Abstract Number: 0749 • ACR Convergence 2025

    Prevalence and characteristics of subclinical Polymyalgia Rheumatica in patients with Giant Cell Arteritis

    Javier Narváez1, Paola Vidal-Montal2, Martí Aguilar-Coll3, Montserrat Roig Kim4, Laia De Daniel Bisbe4, Monica Cubells5, Aina Fabregat6, Judith Palacios-Olid3, Pol Maymó-Paituvi4, Carmen Moragues3 and Joan Miquel Nolla4, 1Hospital Universitario de Bellvitge, Barcelona, Spain, 2Rheumatology. Hospital Universitari de Bellvitge, Barcelona, Catalonia, Spain, 3Department of Rheumatology. Hospital Universitario de Bellvitge, Barcelona, Spain, 4Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Spain, 5Hospital Universitari de Bellvitge, Barcelona, Spain, 6Department of Rheumatology. Hospital Universitario de Bellvitge., Barcelona, Spain

    Background/Purpose: In clinical practice, 18F-FDG PET-CT often reveals findings suggestive of polymyalgia rheumatica (PMR) in patients with giant cell arteritis (GCA) who lack symptoms or…
  • Abstract Number: 1910 • ACR Convergence 2025

    Clinical profile and healthcare resource utilization of patients diagnosed with giant cell arteritis or polymyalgia rheumatica in the US: a real-world cohort study using a large database of administrative health claims

    Julie Mouchet1, Tim Nguyen2, Valeria Jordan M.3, G S Ramakrishna4, Linda Grinnell-Merrick2, Andrew Heaney5, Anushka Mitra Das5, Pooja Shah6 and Evi Zhuleku7, 1Novartis Pharma AG, Basel, Switzerland, 2Novartis Pharmaceuticals Corporation, East Hanover, NJ, 3Novartis Pharmaceuticals Corporation, Tenafly, NJ, 4Novartis Healthcare Private Limited, Hyderabad, India, 5Novartis Ireland Ltd, Dublin, Ireland, 6Cytel Inc, Cambridge, ON, Canada, 7Cytel Inc, Berlin, Germany

    Background/Purpose: Polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) are systemic inflammatory conditions which predominantly affect individuals over the age of 50 years. The conditions…
  • Abstract Number: 0752 • ACR Convergence 2025

    Characterization of patients with polymyalgia rheumatica in the ARTESER giant cell arteritis cohort

    Maite Silva-Diaz1, Marta Domínguez-Álvaro2, Rafael B. Melero-González3, Elisa Fernández-Fernández4, Jesús Alejandro Valero5, Ismael González6, Julio Sánchez Martín7, Javier Narváez8, Eva Galíndez Agirregoikoa9, Vicente Aldasoro Cáceres10, lydia Abasolo Alcazar11, Javier Loricera12, Noemí Garrido13, Santos Castañeda14, Carlota L Iñiguez15, Alicia Garcia16, Clara Molina Almela17, María Alcalde Villar18, Antonio Juan Mas19 and Ricardo Blanco20, 1Complexo Hospitalario Universitario A Coruña, A Coruña, Galicia, Spain, 2Sociedad Española de Reumatología, Madrid, Spain, 3COMPLEXO HOSPITALARIO UNIVERSITARIO DE OURENSE, O Carballino, Spain, 4Hospital Universitario La Paz, Madrid, Spain, 5Hospital Universitario Donosti, Donosti, Spain, 6Complejo Asistencial Universitario de León, León, Castilla y Leon, Spain, 7Hospital Universitario 12 de Octubre, Madrid, Spain, 8Hospital Universitario de Bellvitge, Barcelona, Spain, 9BASURTO UNIVERSITY HOSPITAL, BILBAO, Spain, 10Hospital Universitario de Navarra, Pamplona, Spain, 11IdISSC. HCSC, Madrid, Madrid, Spain, 12Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander , Spain, Santander, Spain, 13Hospital Universitario Virgen del Rocío, Sevilla, Andalucia, Spain, 14Hospital Universitario de La Princesa, IIS-Princesa, Madrid, Madrid, Spain, 15Hospital del Bierzo, Ponferrada, Castilla y Leon, Spain, 16Rheumatologist, La Laguna, Spain, 17Consorci Hospital General Universitari de València, Valencia, Spain, 18Department of Rheumatology, Hospital Universitario Severo Ochoa, Madrid, Spain, Madrid, Spain, 19Hospital Universitari Son Llàtzer, Palma de Mallorca, Spain, 20Rheumatology Division, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander, Spain, Santander, Cantabria, Spain

    Background/Purpose: Giant cell arteritis (GCA) is a chronic granulomatous vasculitis affecting medium- and large-sized arteries (1). The classic symptoms are cranial symptoms, including headache, jaw…
  • Abstract Number: 1987 • ACR Convergence 2025

    Evaluating User Engagement and Real-World Impact of a PMR-Specific Digital Symptom Assessment Tool: A 12-Month Analysis of PainSpot™

    Shilpa Venkatachalam1, Erik Stone2, Ian Carroll3, angela Degrassi3, Shelley Fritz4 and David Curtis5, 1Global Healthy Living Foundation, New York, NY, 2Global Healthy Living Foundation, Nyack, NY, 3Global Healthy Living Foundation, Upper Nyack, NY, 4Global Healthy Living Foundation, Kalaheo, HI, 5Global Healthy Living Foundation, Meriden

    Background/Purpose: Polymyalgia rheumatica (PMR) is a systemic inflammatory condition affecting individuals over 50, marked by bilateral shoulder and hip stiffness and pain. Its nonspecific symptoms…
  • Abstract Number: 0753 • ACR Convergence 2025

    Incidence of Ischemic Vision Loss Among Patients with Polymyalgia Rheumatica and Giant Cell Arteritis

    Mary Peng1, Kylie Carlson2, Sebastian E Sattui3 and Michael Putman4, 1Medical College of Wisconsin, Wauwatosa, WI, 2Medical College of Wisconsin, Milwaukee, WI, 3Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 4The Medical College of Wisconsin, Milwaukee, WI

    Background/Purpose: Ischemic vision loss affects up to one quarter of patients with giant cell arteritis (GCA). The incidence of ischemic vision loss among patients with…
  • Abstract Number: 2109 • ACR Convergence 2025

    Comparative Effects of IL-6 inhibition, Methotrexate, and Glucocorticoid Monotherapy on Bone Mineral Density, 3D-DXA femoral structure and Bone Turnover Markers in GCA and PMR

    Edgar Wiebe1, Lien Meerkatt2, Andriko Palmowski3, Zhivana Boyadzhieva4, Kerstin Rubarth5, Sandra Hermann1, Burkhard Muche3, Gerhard Krönke6 and FRANK BUTTGEREIT7, 1Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany, Berlin, Berlin, Germany, 2Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin, Berlin, Germany, 3Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, 4Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Berlin, Germany, 5Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Berlin, Germany, 6Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany; Deutsches Rheuma-Forschungszentrum Berlin, Berlin, Germany, Berlin, Berlin, Germany, 7Charité University Medicine Berlin, Berlin, Berlin, Germany

    Background/Purpose: Individuals with giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are at increased risk for osteoporosis and fragility fractures due to long-term glucocorticoid (GC)…
  • Abstract Number: 1020 • ACR Convergence 2025

    Cohort Study of European Ancestry, Geographic Region, Ambient Ultraviolet Irradiance and the Risk of Developing Polymyalgia Rheumatica among Women

    Karen H. Costenbader1, Nicole Yang2, Emily Oakes2, Maura Raymo3 and Jae Kang3, 1Harvard Medical School and Brigham and Women's Hospital, Boston, MA, 2Brigham and Women's Hospital, Boston, MA, 3Brigham and Women's Hospital, Boston

    Background/Purpose: Polymyalgia rheumatica (PMR) is one of the most common inflammatory rheumatic diseases among older women, but little is known of its etiology, and there…
  • Abstract Number: 2340 • ACR Convergence 2025

    Lighten the Load: Artificial Intelligence Reveals Body Mass Index Outranks Treatment in One-Year Psoriatic Arthritis Outcomes—Findings from the SPEED Trial

    Alexander Garaiman1, Sophia Massa1, Elnaz Saeedi2, Nicola Gullick3, William Tillett4, Raphaël Hurtubise1, jean-guillaume letarouilly5 and Laura Coates6, 1Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK., Oxford, United Kingdom, 2Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK., Oxford, 3Rheumatology Department, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK, Coventry, United Kingdom, 4Department of Life Sciences, Centre for Therapeutic Innovation, University of Bath, Bath, United Kingdom, 5Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK, Oxford, United Kingdom, 6Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, England, United Kingdom

    Background/Purpose: Personalizing care in early psoriatic arthritis (PsA) is challenging. We set out to identify predictors of one-year response on the PASDAS using AI-based methods…
  • Abstract Number: 0756 • ACR Convergence 2024

    Effectiveness and Safety of Tocilizumab in the Treatment of Polymyalgia Rheumatica: A Meta-Analysis

    Ali Raza Khan1, Nouman Shafique2, Abdul Qadeer1 and zaigham Shaukat1, 1Nishtar Medical University, Multan, Punjab, Pakistan, 2AdventHealth Orlando, Orlando, FL

    Background/Purpose: Giant Cell Arteritis (GCA) and Polymyalgia Rheumatica (PMR) are different manifestations of the same disease process. GCA is a vasculitis that affects large and…
  • Abstract Number: 1698 • ACR Convergence 2024

    Assessment of the Remission Maintenance After Tocilizumab Withdrawal in Polymyalgia Rheumatica Patients Receiving a 6-month Treatment

    Baptiste Chevet1, Aghiles Souki2, nowak emmanuel2, Guillermo CARVAJAL ALEGRIA3, Emmanuelle Dernis4, Christophe Richez5, Marie-Elise Truchetet6, DANIEL WENDLING7, ERIC TOUSSIROT8, aleth Perdriger9, Jacques-Eric Gottenberg10, Renaud FELTEN11, Bruno Fautrel12, laurent chiche13, Anne Walliser-Lohse14, Pascal Hilliquin15, Catherine Le Henaff16, Benjamin Dervieux17, Guillaume Direz18, Isabelle Valckenaere19, Divi Cornec20, Dewi Guellec21, Thierry Marhadou22, Alain SARAUX23 and Valerie Devauchelle24, 1University Hospital of Brest, Brest, France, 2Centre Hospitalier Regional Universitaire (CHU) de Brest, Brest, France, 3CHRU de Tours, Tours, France, 4CH LE MANS, LE MANS, Pays de la Loire, France, 5Université de Bordeaux, Bordeaux, France, 6Bordeaux University Hospital, Bordeaux, France, 7University Hospital, Besançon, France, 8university hospital of BESANCON, besancon, France, 9Rennes University, Rennes, France, 10Rheumatology Department, Strasbourg University Hospital,, Strasbourg, France, 11Hopitaux Universitaires de Strasbourg, STRASBOURG, France, 12INSERM, UMRS 1136, Institut Pierre Louis d'Epidémiologie et de Santé Publique, and Sorbonne University – Assistance Publique-Hôpitaux de Paris, Département de Rhumatologie, Hôpital Pitié-Salpêtrière, Paris, Ile-de-France, France, 13hopital europeen, marseille, France, 14Hopital Nord Franche-Comté, BELFORT, France, 15Centre Hospitalier Sud Francilien, Corbeil-Essonnes, France, 16Hopital de Morlaix, Morlaix, France, 17CH de Mulhouse - Competence center for autoimmune diseases, Internal Medicine, Mulhouse, France, 18Hôpital du Mans, Le Mans, France, 19CHU de Nancy, Nancy, France, 20Service de Rhumatologie, CHU de Brest, Brest, France, 21CHU de Brest, Brest, France, 22CHU Cavale Blanche, Brest, France, 23CHU Brest, Brest, France, 24UBO, Brest, France

    Background/Purpose: The SEMAPHORE trial1 was a randomized controlled prospective study to assess the safety and efficacy (success defined by PMR-AS≤10 and GC≤5mg or GC decrease…
  • Abstract Number: 0762 • ACR Convergence 2024

    Different Giant Cell Arteritis Phenotypes May Present Distinct Types of Ischemic Complications

    Helena M Amar Muñoz1, Juan Molina-Collada1, Isabel Castrejon2, irene monjo3, Elisa Fernández-Fernández:4, José María Álvaro-Gracia5 and Eugenio De Miguel6, 1Hospital General Universitario Gregorio Marañón, MADRID, Spain, 2Hospital General Universitario Gregorio Marañon, Madrid, Spain, 3University Hospital La Paz, Madrid, Spain, 4La Paz University Hospital, Alcalá de Henares, Madrid, Spain, 5Hospital Gregorio Marañón, Madrid, Spain, 6Hospital Universitario La Paz, Madrid, Spain

    Background/Purpose: To determine if the subtype of vascular ultrasound (US) presentation is associated with different types of ischemic complications (IC) in giant cell arteritis (GCA).Methods: Retrospective…
  • Abstract Number: 1700 • ACR Convergence 2024

    Comparative Effectiveness of Sarilumab vs. Methotrexate as a Glucocorticoid-Sparing Agent in Patients with Polymyalgia Rheumatica

    Jeffrey Curtis1, Fenglong Xie2, Shanette Daigle3 and Sebastian E. Sattui4, 1The University of Alabama at Birmingham, Birmingham, AL, 2University of Alabama at Birmingham, Birmingham, AL, 3FASTER, Birmingham, AL, 4University of Pittsburgh, Pittsburgh, PA

    Background/Purpose: Polymyalgia rheumatica (PMR) is an inflammatory condition that typically affects older individuals for whom long term glucocorticoid (GC) use may be undesirable. Moreover, the…
  • Abstract Number: 0768 • ACR Convergence 2024

    Addressing Gaps in Polymyalgia Rheumatica: A Systematic Literature Review

    Shelley Fritz1, Angela Degrassi2, Kelly Gavigan2, Ruohan Hong3, Santiago Munoz Perez2, Esteban Rivera4, Erik Stone5, Laura Stradford6, Ambika Vartak2, Anne Sydor2 and Shilpa Venkatachalam3, 1Global Healthy Living Foundation, Kalaheo, HI, 2Global Healthy Living Foundation, Upper Nyack, NY, 3Global Healthy Living Foundation, New York, NY, 4Global Healthy Living Foundation, Long Island City, NY, 5Global Healthy Living Foundation, Upper Nyack, 6Global Healthy Living Foundation, Nyack, NY

    Background/Purpose: This systematic literature review on polymyalgia rheumatica (PMR) and PMR with giant cell arteritis (GCA) evaluates existing literature on disease burden, management, and treatment…
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