Abstract Number: 2997 • 2015 ACR/ARHP Annual Meeting
A Genome-Wide Association Study of a Hispanic Systemic Sclerosis Cohort
Background/Purpose: Genome-wide association studies (GWASs) have resulted in the identification of several genetic loci involved in systemic sclerosis (SSc) susceptibility. However, GWASs are normally focused…Abstract Number: 1130 • 2014 ACR/ARHP Annual Meeting
IRF8 Gene Contributes to Disease Susceptibility and Interacts with NF-KB By Modulating Interferon Signature in Patients with Systemic Sclerosis
Background/Purpose . Systemic Sclerosis (SSc) is a polygenic autoimmune disease (AID) characterized by fibroblast dysregulation. It shares some genetic bases with other AIDs, as evidenced…Abstract Number: 745 • 2014 ACR/ARHP Annual Meeting
Genetic Susceptibility Loci of Idiopathic Interstitial Pneumonitis Do Not Represent Risk for Systemic Sclerosis
Background/Purpose: Systemic sclerosis (SSc) related interstitial lung disease (ILD) has phenotypic similarities to idiopathic interstitial pneumonia (IIP). The objective of this study was to assess…Abstract Number: 86 • 2014 ACR/ARHP Annual Meeting
Association of Leukocyte Immunoglobulin-like Receptor A3 (LILRA3) with Systemic Sclerosis
Background/Purpose: The leukocyte immunoglobulin-like receptors (LILRs) are a gene family located in leukocyte receptor complex at 19q13.4. LILRs are expressed mainly in immune cells as…Abstract Number: 701 • 2012 ACR/ARHP Annual Meeting
Vascular Differences Associated to Genetic Polymorphisms of Endothelial Nitric Oxide Synthase in Mexican Patients with Systemic Sclerosis. A Preliminary Report
Background/Purpose: Vascular dysfunction usually is observed before clinically detectable fibrosis of systemic sclerosis (SSc). The eNOS catalyses the synthesis of nitric oxide (NO), which maintains…