Abstracts tagged "polymorphism and pulmonary complications"

Abstract Number: 3005 • 2015 ACR/ARHP Annual Meeting
Pulmonary Arterial Hypertension-Associated Single Nucleotide Polymorphisms of Hypoxia-Inducible Factor-3a Gene Cause Constitutive Activation of the Endothelin-1 Gene Promoter
Katsutoshi Mizumoto¹, Kyohei Takatori¹, Sayaka Takatori¹, Ryota Yoshimoto¹, Kohei Eguchi¹, Daisuke Fujishiro¹, Satoru Kodama¹, Atsushi Kobayashi¹, Kensaku Okamoto¹, Yasushi Kawaguchi², Masakazu Haneda¹ and Yuichi Makino¹, ¹Division of Metabolism and Biosystemic Science, Department of Medicine, Asahikawa Medical University, Asahikawa, Japan, ²Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan
Background/Purpose: Pulmonary arterial hypertension (PAH) is a progressive and fatal complication in the patients with connective tissue diseases (CTD). Elevation of endothelin-1 (ET-1) levels in…

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Abstracts tagged "polymorphism and pulmonary complications"

Pulmonary Arterial Hypertension-Associated Single Nucleotide Polymorphisms of Hypoxia-Inducible Factor-3a Gene Cause Constitutive Activation of the Endothelin-1 Gene Promoter