Abstracts tagged "polymorphism and genetics"

Abstract Number: 1955 • 2019 ACR/ARP Annual Meeting
Association of TERT and DSP Polymorphisms with Susceptibility to Myeloperoxidase-ANCA-Associated Vasculitis
Aya Kawasaki¹, Natsumi Namba ¹, Ken-ei Sada ², Fumio Hirano ³, Shigeto Kobayashi ⁴, Hidehiro Yamada ⁵, Hiroshi Furukawa ⁶, Kenji Nagasaka ⁷, Takahiko Sugihara ⁸, Aika Suzuki ⁹, Kunihiro Yamagata ¹⁰, Takayuki Sumida ¹¹, Shigeto Tohma ¹², Sakae Homma ¹³, Shoichi Ozaki ¹⁴, Hiroshi Hashimoto ¹⁵, Hirofumi Makino ¹⁶, Yoshihiro Arimura ¹⁷, Masayoshi Harigai ¹⁸ and Naoyuki Tsuchiya ¹, ¹Molecular and Genetic Epidemiology Laboratory, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan, ²Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Kitaku, Okayama, Japan, ³Department of Rheumatology, Tokyo Medical and Dental University, Tokyo, Japan, ⁴Department of Internal Medicine, Juntendo University Koshigaya Hospital, Koshigaya, Japan, ⁵Center for Rheumatic diseases, Seirei Yokohama Hospital, Kawasaki, Japan, ⁶Molecular and Genetic Epidemiology Laboratory, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan, ⁷Department of Rheumatology, Ome Municipal General Hospital, Tokyo, ⁸Department of Lifetime Clinical Immunology, Tokyo Medical and Dental University, Tokyo, Japan, ⁹Department of Respiratory Medicine, Toho University Graduate School of Medicine, Tokyo, Japan, ¹⁰Department of Nephrology, University of Tsukuba, Tsukuba, Ibaraki, Japan, ¹¹Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan, ¹²National Hospital Organization Tokyo National Hospital, Kiyose, Japan, ¹³Department of Advanced and Integrated Interstitial Lung Diseases Research, School of Medicine, Toho University, Tokyo, Japan, ¹⁴St. Marianna University School of Medicine, Kawasaki, Japan, ¹⁵Juntendo University School of Medicine, Tokyo, Japan, ¹⁶Okayama University, Okayama, Japan, ¹⁷Nephrology and Rheumatology, Kyorin University School of Medicine, Tokyo, Japan, ¹⁸Department of Rheumatology, Tokyo Women's Medical University School of Medicine, Shinjuku-ku, Tokyo, Japan
Background/Purpose: Epidemiology of ANCA-associated vasculitis (AAV) is substantially different between East Asian and European populations. Microscopic polyangiitis (MPA) and MPO-ANCA positive AAV (MPO-AAV) are prevalent…

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