ACR Meeting Abstracts

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Abstracts tagged "polyangiitis and vasculitis"

  • Abstract Number: 2725 • 2018 ACR/ARHP Annual Meeting

    Clinical Characteristics and Long-Term Follow-up of 382 Microscopic Polyangiitis Patients

    Yann Nguyen1, Christian Pagnoux2, Alexandre Karras3, Thomas Quémeneur4, Francois Maurier5, Mohamed Hamidou6, Alain Le Quellec7, Noémie Jourde-Chiche8, Pascal Cohen1, Alexis Régent1, François Lifermann9, Arsène Mékinian10, Chahéra Khouatra11, Eric Hachulla12, Jacques Ninet13, Jacques Pourrat14, Marc Ruivard15, Pascal Godmer16, Jean-Francois Viallard17, Benjamin Terrier1, Luc Mouthon1, Loïc Guillevin1 and Xavier Puéchal1, 1Department of Internal Medicine, Referral Center for Rare Autoimmune and Systemic Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France, Paris, France, 2Division of Rheumatology, Division of Rheumatology, Mount Sinai Hospital, Toronto, ON, Canada, 3Department of Nephrology, Hôpital Européen Georges Pompidou, APHP, Paris, France, Paris, France, 4Department of Internal Medicine, CH of Valenciennes, France, Valenciennes, France, 5Médecine interne, Hôpitaux Privés de Metz, Metz, France, 6Department of Internal Medicine, CHU de Nantes, France, Nantes, France, 7Department of Internal Medicine, Hôpital Saint-Eloi, CHU de Montpellier, France, Montpellier, France, 8Nephrology, Department of Nephrology, AP-HM, CHU Conception, Marseille, France, Marseille, France, 9Dax, Dax, France, 10Department of Internal Medicine, Hôpital Saint-Antoine, APHP, Paris, France, Paris, France, 11Department of Respiratory Medicine, National Reference Center for Rare Pulmonary Diseases, Hospices civils de Lyon, Hôpital Louis Pradel, Lyon, France, Lyon, France, 12Department of Internal Medicine, National Reference Center for Systemic Sclerosis, Hôpital Claude Huriez, CHRU Lille, France, Lille, France, 13Department of Internal Medicine, Hôpital Edouard Herriot HCL, CHU de Lyon, France, Lyon, France, 14Department of Nephrology, Hôpital de Rangueil, CHU Toulouse, France, Toulouse, France, 15Department of Internal Medicine, CHU Estang, Clermont-Ferrand, France, Clermont-ferrand, France, 16Department of Internal Medicine, CH Vannes, France, Vannes, France, 17Department of Internal Medicine, Hôpital Haut-Lévêque, Bordeaux, France, CHU Bordeaux, France

    Background/Purpose: Microscopic polyangiitis (MPA) is a systemic ANCA-associated small-vessel necrotizing vasculitis characterized by general symptoms, and visceral manifestations, including rapidly progressive glomerulonephritis and alveolar hemorrhage.…
  • Abstract Number: 893 • 2017 ACR/ARHP Annual Meeting

    Efficacy and Safety of Belimumab in Combination with Azathioprine for Remission Maintenance in Granulomatosis with Polyangiitis and Microscopic Polyangiitis: A Multicenter Randomized, Placebo-Controlled Study

    David Jayne1, Daniel Blockmans2, Raashid Luqmani3, Beulah Ji4, Yulia Green5, Leanne Hall6, David Roth7 and Peter A. Merkel8, 1Vasculitis and Lupus Clinic, Department of Medicine, University of Cambridge, Cambridge, United Kingdom, 2General Internal Medicine, University Hospital Gasthuisberg, Leuven, Belgium, 3Botnar Research Centre, University of Oxford, Oxford, United Kingdom, 4GSK Stockley Park, Uxbridge, United Kingdom, 5GSK Stockley Park, Stockley Park, United Kingdom, 6GSK Stevenage, Stevenage, United Kingdom, 7GSK Collegeville, Collegeville, PA, 8Division of Rheumatology, University of Pennsylvania, Philadelphia, MN

    Background/Purpose: GPA (Wegener’s) and MPA are organ- and life-threatening systemic vasculitides characterized by the presence of ANCA-associated vasculitis (AAV), implicating B cells in disease pathogenesis.…
  • Abstract Number: 1770 • 2017 ACR/ARHP Annual Meeting

    ANCA-Associated Vasculitis (AAV) in Younger Vs Older Patients:  Comparison of Clinical, Serologic and Outcome Differences and Their Implications for Management

    Priya Chokshi1, Olufemi Aina2, Naveed Masani2, Melissa Fazzari3, Elise Belilos1, Kristina Belostocki1, Gary Rosenblum1, Tobin Abraham4, Daniil Shimonov4, Zinal Patel4 and Steven E. Carsons1, 1Rheumatology, NYU Winthrop Hospital, Mineola, NY, 2Nephrology, NYU Winthrop Hospital, Mineola, NY, 3Biostatistics, NYU Winthrop Hospital, Mineola, NY, 4Medicine, NYU Winthrop Hospital, Mineola, NY

    Background/Purpose: ANCA-associated vasculitis (AAV) is a cause of multi-organ disease in all ages, but peaks at ages 65-74. Limited data is available on the characteristics…
  • Abstract Number: 1777 • 2017 ACR/ARHP Annual Meeting

    Incidence and Prevalence of Granulomatosis with Polyangiitis and Microscopic Polyangiitis in a Health Management Organization: A 15-Year Study

    Florencia Pierini1, Marina Scolnik1, Valeria Scaglioni2, Florencia Beatriz Mollerach3 and Enrique R. Soriano1, 1Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, CABA, Argentina, 2Rheumatology Unit, Internal Medicine Service. Hospital Italiano de Buenos Aires, CABA, Argentina, 3Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina

    Background/Purpose: ANCA-associated vasculitides are rare diseases and epidemiological data on them is scarce. Our objective was to estimate incidence and prevalence rates of Granulomatosis with…
  • Abstract Number: 2737 • 2017 ACR/ARHP Annual Meeting

    Pulmonary Manifestations of Primary Systemic Vasculitides

    Jean-Paul Makhzoum1, Raashid Luqmani2, Richard A. Watts3, Anthea Craven4, Peter A. Merkel5 and Christian Pagnoux6, 1Rheumatology, Vasculitis Clinic, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, 2Botnar Research Centre, University of Oxford, Oxford, United Kingdom, 3Rheumatology Department, The Ipswich Hospital, Ipswich, Great Britain, 4Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, Oxford University Hospitals, Oxford, United Kingdom, 5Division of Rheumatology, University of Pennsylvania; Perelman School of Medicine, Philadelphia, PA, 6Rheumatology-Vasculitis clinic, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada

    Background/Purpose: Pulmonary involvement in systemic primary vasculitides is diverse and occurs with variable incidence depending on the type of vasculitis. This study aimed to describe…
  • Abstract Number: 738 • 2013 ACR/ARHP Annual Meeting

    Pulmonary Fibrosis In ANCA-Associated Vasculitis

    Cloé Comarmond1, Bruno Crestani2, Abdellatif Tazi3, Baptiste Hervier4, Sylvain Adam-Marchand5, Hilario Nunes6, Fleur Cohen-Aubart7, Marie Wislez8, Jacques Cadranel8, Bruno Housset9, Célia Lloret-Linares10, Pascal Sève11, Christian Pagnoux12, Sébastien Abad13, Juliette Camuset14, Boris Bienvenu15, Michael Duruisseaux16, Eric Hachulla17, Jean-Benoît Arlet18, Mohamed Hamidou19, Alfred Mahr20, Anne-Laure Brun21, Philippe Grenier21, Patrice Cacoub22 and David Saadoun23, 1Internal Medicine and Clinical Imunology, Referal Center for Autoimmune diseases, Internal Medicine and Clinical Imunology, Hôpital Pitié Salpétrière, Paris, France, 2Pneumology A, Hôpital Bichat, Paris, France, 3Hôpital Saint-Louis, Paris, France, 4Internal Medicine & Clinical Immunology Dpt, Pitié-Salpêtrière Hospital, APHP, Paris, France, 5Pneumology, Centre Hospitalier Universitaire de Tours, Tours, France, 6Department of Pneumology, Avicenne Hospital (AP-HP), Bobigny, France, 7Internal Medicine Dpt 2, Pitié-Salpêtrière Hospital, APHP, Paris, France, 8Pneumology, Hôpital Tenon, Paris, France, 9Pneumology, Centre Hospitalier Intercommunal de Créteil, Créteil, France, 10Médecine Interne A, Hôpital Lariboisière, Paris, France, 11Internal medicine, CHU Lyon, Lyon, France, 12Rheumatology, Mount Sinai Hospital, Toronto, Canada, Toronto, ON, Canada, 13Internal Medicine, Avicenne Hospital, Bobigny, France, 14Pneumology, Centre Hospitalier Victor Dupouy, Argenteuil, France, 15Division of Internal Medicine, Centre Hospitalier Régional Universitaire de Caen, Côte de Nacre, Caen, France, Caen, France, 16Pneumology, CHU de Grenoble, Grenoble, France, 17Internal Medicine, Lille CEDEX, France, 18Internal Medicine, HEGP, Paris, France, 19Internal Medicine Department, Nantes University Hospital, Nantes, France, 20Department of Internal Medicine, Hospital Saint-Louis, Paris, France, 21Radiology, Hôpital Pitié-Salpêtrière, Paris, France, 22Médecine Interne 2, Hopital Pitié-Salpétrière, Paris, France, 23Groupe Hospitalier Pitié Salpétrière, Service de Médecine Interne, DHU i2B, Paris, France

    Background/Purpose: The association of pulmonary fibrosis (PF) with anti neutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV), especially microscopic polyangiitis (MPA), is rare but related to poor…
  • Abstract Number: 1540 • 2012 ACR/ARHP Annual Meeting

    Practice Patterns in the Treatment of ANCA-Associated Vasculitis: Exploring Differences Among Subspecialties At a Single Academic Medical Center

    Lindsy J. Forbess1, Kenneth W. Griffin2 and Robert F. Spiera3, 1Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, 2Public Health, Weill Cornell Medical College, New York, NY, 3Rheumatology, Hospital for Special Surgery, New York, NY

    Background/Purpose: Randomized controlled trial evidence helps guide physician treatment choices for ANCA-Associated Vasculitis (AAV). Data for remission maintenance therapy following rituximab (RTX) in generalized disease,…
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