Abstracts tagged "platelets and Pathophysiology"

Abstract Number: 2812 • 2019 ACR/ARP Annual Meeting
A New Role for Selectins in Systemic Lupus Erythematosus
Marc SCHERLINGER¹, Vivien Guillotin ², Pierre Vacher ³, Vanja Sisirak ⁴, isabelle Douchet ⁴, Nathalie Merillon ⁴, Pierre Duffau ⁵, Estibaliz Lazaro ⁶, Emmanuel Ribeiro ⁷, Christophe Richez ⁸ and Patrick BLANCO ⁹, ¹CHU de Bordeaux, Immunoconcept, Bordeaux, France, ²CHU de Bordeaux, Bordeaux, France, ³INSERM ACTION U1218, Bordeaux, France, ⁴Immunoconcept, Bordeaux, France, ⁵Department of Internal Medicine and Clinical Immunology , Hôpital Saint-André, CHU de Bordeaux , Bordeaux , France., Bordeaux, Aquitaine, France, ⁶FHU ACRONIM, Department of Internal Medecine, Centre Hospitalier Universitaire, Bordeaux, France, Pessac, France, ⁷CHU de Bordeaux, Bordeaux, ⁸Pellegrin Hospital, University Hospital of Bordeaux, Bordeaux, France, ⁹CNRS-UMR 5164 - ImmunoConcEpt, Bordeaux University - Immunology and Immunogenetic Department Bordeaux University Hospital, Bordeaux, Aquitaine, France
Background/Purpose: In systemic lupus erythematosus (SLE), blood platelets have an activated phenotype, and express high levels of CD40L and P-selectin. Our group demonstrated that SLE…

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