Abstracts tagged "Plasmablasts and rheumatoid arthritis (RA)"

Abstract Number: 1094 • 2015 ACR/ARHP Annual Meeting
Increased IgA Plasmablasts Are Associated with Rheumatoid Arthritis-Related Autoantibodies in the Absence of Inflammatory Arthritis
Jennifer Kinslow¹, Lisa Blum², Kevin D. Deane³, Kristen Demoruelle⁴, Mark C. Parish⁵, Sarah Kongpachith⁶, Lauren J. Lahey⁷, Jill M. Norris^8,9, William H. Robinson¹⁰ and V. Michael Holers¹¹, ¹Rheumatology, University of Colorado, Aurora, CO, ²Stanford University, Palo Alto, CA, ³Division of Rheumatology, U Colo Denver, Aurora, CO, ⁴Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, ⁵Rheumatology, University of Colorado Anschutz Medical Campus, Aurora, CO, ⁶Medicine, Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, ⁷Medicine, VA Palo Alto HealthCare System and Stanford University, Palo Alto, CA, ⁸University of Colorado Denver, Aurora, CO, ⁹Epidemiology, Colorado School of Public Health, Aurora, CO, ¹⁰Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, ¹¹Rheumatology Division, Univ of Colorado School of Med, Aurora, CO
Background/Purpose: Rheumatoid Arthritis (RA) autoimmunity starts years before clinically apparent inflammatory arthritis (IA) develops, and elevated disease-specific autoantibodies, including anti-citrullinated protein antibodies (ACPA) and rheumatoid…

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