Abstracts tagged "plasma cells and scleroderma"

Abstract Number: 1760 • 2012 ACR/ARHP Annual Meeting
A Gene Expression Signature to Monitor Depletion of Plasma Cells Following MEDI-551 (anti-CD19) Administration
Katie Streicher¹, Chris Morehouse¹, Christopher Groves², Bhargavi Rajan², Fernanda Pilataxi¹, Kim Lehmann¹, Philip Brohawn¹, Kathleen McKeever³, Volker Knappertz⁴, Ronald Herbst², Yihong Yao¹ and Koustubh Ranade¹, ¹Translational Sciences, MedImmune, LLC, Gaithersburg, MD, ²Respiration, Inflammation and Autoimmunity, MedImmune, LLC, Gaithersburg, MD, ³Translational Sciences, MedImmune, Gaithersburg, MD, ⁴Clinical, MedImmune, LLC, Gaithersburg, MD
Background/Purpose: Production of pathogenic autoantibodies by inappropriately self-reactive plasma cells (PC) is a hallmark of autoimmune diseases. MEDI-551 is an anti-CD19 antibody which is expected…

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Abstracts tagged "plasma cells and scleroderma"

A Gene Expression Signature to Monitor Depletion of Plasma Cells Following MEDI-551 (anti-CD19) Administration