Abstracts tagged "phenotypes and psoriatic arthritis"

Abstract Number: 684 • 2018 ACR/ARHP Annual Meeting
Efficacy of Ixekizumab in Different Phenotypes of Patients with Active Psoriatic Arthritis (PsA): Results from the Spirit Trials
Frank Behrens¹, Peter Nash², Laure Gossec³, Soyi Liu Leage⁴, Inmaculada de la Torre⁵, Christophe Sapin⁴, Monika Kurzawa⁶, Gerd R. Burmester⁷ and Josef S. Smolen⁸, ¹Division of Rheumatology, Goethe University and Fraunhofer IME-TMP, Frankfurt, Germany, ²University of Queensland, Brisbane, Australia, ³Sorbonne Universités, Paris, France, ⁴Lilly France, Neuilly sur Seine Cedex, France, Neuilly sur Seine Cedex, France, ⁵Eli Lilly and Company, Madrid, Spain, ⁶Eli Lilly and Company, Bad Homburg, Germany, ⁷Department of Rheumatology and Clinical Immunolgy, Charité University Hospital, Berlin, Germany, ⁸Division of Rheumatology, Department of Medicine 3, Medical University of Vienna, Vienna, Austria
Background/Purpose: PsA is a highly heterogeneous chronic inflammatory disease combining a range of musculoskeletal and extra-articular manifestations. Ixekizumab (IXE) is approved for the treatment of…
Abstract Number: 1625 • 2018 ACR/ARHP Annual Meeting
Association of HLA-B Type and Sacroiliitis in Patients with Psoriatic Arthritis
Daniel Kuo¹, Isela Valera², Mihaela Taylor¹, Roy Altman¹, Veena K. Ranganath¹, Thanda Aung¹, James Louie¹ and Suzanne Kafaja¹, ¹Rheumatology, UCLA David Geffen School of Medicine, Los Angeles, CA, ²Autoimmunity and Tolerance Laboratory, Division of Rheumatology, Department of Medicine, UCLA David Geffen School of Medicine, Los Angeles, CA
Background/Purpose: Psoriatic arthritis (PsA) is a heterogeneous disease with strong genetic heritability. Class I major histocompatibility complex (MHC) genes have been associated with PsA phenotype…
Abstract Number: 2720 • 2016 ACR/ARHP Annual Meeting
Genome-Wide Association Study of Clinical Phenotypes in Psoriatic Arthritis
Juan D. Cañete¹, Jose A Pinto-Tasende², Jordi Gratacós³, Rubén Queiro⁴, Carlos Alberto Montilla Morales⁵, Juan Carlos Torre-Alonso⁶, Jose Javier Perez Venegas⁷, Antonio Fernandez-Nebro⁸, Santiago Muñoz⁹, Carlos Gonzalez¹⁰, Daniel Roig¹¹, Pedro Zarco¹², Alba Erra¹³, Jesus Rodriguez¹⁴, Santos Castañeda¹⁵, Esteban Rubio-Romero¹⁶, Georgina Salvador¹⁷, Cesar Diaz-Torné¹⁸, Ricardo Blanco¹⁹, Alfredo Willisch²⁰, Jose Antonio Mosquera²¹, Paloma Vela²², Jesús Tornero²³, Simon Sanchez Fernandez²⁴, Hector Corominas²⁵, Julio Ramírez²⁶, Maria López-Lasanta²⁷, Mireia López²⁸, Raül Tortosa²⁹, Antonio Julià²⁹ and Sara Marsal³⁰, ¹Rheumatology Department, Hospital Clínic de Barcelona, Barcelona, Spain, ²Rheumatology Division, INIBIC-Complejo Hospitalario Universitario A Coruña (CHUAC), A Coruna, Spain, ³Rheumatology, Hospital de Sabadell, Sabadell, Spain, ⁴H Central de Asturias, Oviedo, Spain, ⁵Rheumatology, HOSPITAL CLÍNICO UNIVERSITARIO DE SALAMANCA, Salamanca, Spain, ⁶H Monte Naranco, Oviedo, Spain, ⁷Rheumatology, Hospital de Jerez de la Frontera, Jerez de la Frontera, Spain, ⁸Rheumatology, Hospital Universitario Carlos Haya, Malaga, Spain, ⁹Rheumatology, Hospital Infanta Sofia, Madrid, Spain, ¹⁰Servicio de Reumatología, Hospital Universitario Gregorio Marañón, MD, PhD, Madrid, Spain, ¹¹Rheumatology Service, Hospital Universitari de Bellvitge, Hospitalet de Llobregat- Barcelona, Spain, ¹²H Fundación Alcorcón, Alcorcón, Spain, ¹³CapiCAT group (Nailfold Capillaroscopy group from the Catalan Society for Rheumatology)., Catalonia, Spain, ¹⁴Rheumatology, Hospital Universitari de Bellvitge, Barcelona, Spain, ¹⁵Rheumatology, Hospital de la Princesa, IIS-IP, Madrid, Spain, ¹⁶Rheumatology, Rheumatology, Seville, Spain, ¹⁷Rheumatology Unit., Hospital Mutua de Terrassa. Barcelona, Barcelona, Spain, ¹⁸Rheumatology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain, ¹⁹Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, ²⁰Complexo Hospitalario de Ourense, Ourense, Spain, ²¹Servicio de Reumatología, Complejo Hospitalario Hospital Provincial de Pontevedra, Pontevedra, Spain, ²²Dpt. Rheumatology, Hospital General Universitario Alicante, Alicante, Spain, ²³Rheumatology Department, Hospital Universitario Guadalajara, Guadalajara, Spain, ²⁴Rheumatology Department, Hospital General La Mancha Centro, Ciudad Real, Spain, ²⁵Rheumatology, Hospital Moises Broggi, Barcelona, Spain, ²⁶Rheumatology, Hospital Clínic, Barcelona, Spain, ²⁷Vall d'Hebron Hospital Research Institute, Barcelona, Spain, ²⁸Servicio de Reumatología, Hospital Universitario Vall d´Hebron, Barcelona, Spain, ²⁹Rheumatology Research Group, Vall d'Hebron Hospital Research Institute, Barcelona, Spain, ³⁰Rheumatology Research Unit, Vall d'Hebron Hospital, Barcelona, Spain
Background/Purpose: Genome-wide association studies (GWAS) in patients and healthy controls have allowed the identification of multiple variants associated with disease risk in Psoriatic Arthritis (PsA).…
Abstract Number: 1575 • 2014 ACR/ARHP Annual Meeting
The Association Between Obesity and Disease Phenotype in Psoriatic Arthritis
Lihi Eder¹, Cheryl Rosen², Vinod Chandran³ and Dafna D. Gladman³, ¹Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²Division of Dermatology, University of Toronto, Toronto western Hospital, Toronto, ON, Canada, ³University of Toronto, Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: Obesity is associated with an increased risk of developing psoriatic arthritis (PsA) in patients with psoriasis. This study aimed to assess whether obesity is…