Abstracts tagged "phenotypes and polymorphism"

Abstract Number: 1953 • 2015 ACR/ARHP Annual Meeting
Identification of Genetic Factors Associated with Clinical Manifestations of Giant Cell Arteritis through a Stratified Large-Scale Analysis
Ana Márquez¹, Francisco David Carmona², Maria C. Cid³, José Hernández-Rodríguez³, Roser Solans⁴, Marc Ramentol⁴, Santos Castañeda⁵, Jose A. Miranda-Filloy⁶, Inmaculada C. Morado⁷, Javier Narváez⁸, Eugenio De Miguel⁹, Bernardo Sopeña¹⁰, Jordi Monfort¹¹, Maria Jesus Garcia-Villanueva¹², Norberto Ortego-Centeno¹³, Miguel Angel Gonzalez-Gay¹⁴, Javier Martín¹⁵ and Spanish GCA Group, ¹Instituto de Parasitología y Biomedicina López-Neyra, IPBLN-CSIC, PTS-Granada and Systemic Autoimmune Diseases Unit, Hospital Clínico San Cecilio, Granada, Spain, ²Instituto de Parasitología y Biomedicina López-Neyra, IPBLN-CSIC, PTS-Granada, Granada, Spain, ³Vasculitis Research Unit, Department of Autoimmune Diseases, Hospital Clínic University of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain, ⁴Autoimmune Systemic Diseases Unit, Department of Internal Medicine, Hospital Vall d’Hebron, Autonomous University of Barcelona, Barcelona, Spain, ⁵Department of Rheumatology, Hospital de la Princesa, IIS-Princesa, Madrid, Spain, ⁶Department of Rheumatology, Hospital Xeral-Calde, Lugo, Spain, ⁷Department of Rheumatology, Hospital Clínico San Carlos, Madrid, Spain, ⁸Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, ⁹Department of Rheumatology, Hospital Universitario La Paz, Madrid, Spain, ¹⁰Department of Internal Medicine, Complejo Hospitalario Universitario de Vigo, Vigo, Spain, ¹¹Department of Rheumatology, Grup de recerca cel•lular en inflamació i cartílag. IMIM (Institut de Recerca Hospital del Mar), Barcelona, Spain, ¹²Department of Rheumatology, Hospital Ramón y Cajal, Madrid, Spain, ¹³Systemic Autoimmune Diseases Unit, Hospital Clínico San Cecilio, Granada, Spain, ¹⁴Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, ¹⁵Instituto de Parasitología y Biomedicina López- Neyra, IPBLN-CSIC, PTS-Granada, Granada, Spain
Background/Purpose: Giant cell arteritis (GCA) is a large-vessel vasculitis that primarily affects the aorta and external carotid arteries and their branches, leading to ischemic manifestations…

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