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Abstracts tagged "pharmacology and systemic lupus erythematosus (SLE)"

  • Abstract Number: 616 • ACR/ARHP Annual Meeting 2012

    Bioavailability, Pharmacokinetics, and Safety of Belimumab Administered Subcutaneously in Healthy Subjects

    Wendy Cai1, Cecil Chen1, Z. John Zhong1, William W. Freimuth1, William Lewis2 and David Subich3, 1Human Genome Sciences, Inc., Rockville, MD, 2Covance Clinical Research Unit, Inc., Dallas, TX, 3Covance Clinical Research Unit, Inc., Daytona Beach, FL

    Background/Purpose: Belimumab is a recombinant, human Ig-G1λ monoclonal antibody that binds and antagonizes the biological activity of soluble B-lymphocyte stimulator protein, a member of the…

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