Abstracts tagged "pharmacokinetics and polymerase chain reaction (PCR)"

Abstract Number: 1828 • 2015 ACR/ARHP Annual Meeting
Target Modulation of a Type I Interferon Gene Signature and Pharmacokinetics of Anifrolumab in a Phase IIb Study of Patients with Moderate to Severe Systemic Lupus Erythematosus
Philip Brohawn¹, Lingning Santiago², Chris Morehouse¹, Brandon Higgs¹, Gabor Illei¹ and Koustubh Ranade¹, ¹MedImmune, Gaithersburg, MD, ²MedImmune, Mountain View, CA
Background/Purpose: Anifrolumab is a fully human IgG1 monoclonal antibody directed against subunit 1 of the type I interferon receptor (IFNAR1). Anifrolumab blocks the binding of…

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Abstracts tagged "pharmacokinetics and polymerase chain reaction (PCR)"

Target Modulation of a Type I Interferon Gene Signature and Pharmacokinetics of Anifrolumab in a Phase IIb Study of Patients with Moderate to Severe Systemic Lupus Erythematosus