ACR Meeting Abstracts

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Abstracts tagged "pharmacokinetics and monoclonal antibodies"

  • Abstract Number: 2574 • 2019 ACR/ARP Annual Meeting

    Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Effect of BIIB059, a Monoclonal Antibody Targeting BDCA2 Following Administration of Subcutaneous Single Doses in Japanese Healthy Volunters

    Cristina Musselli1, Francois Gaudreault 1, Naik Himanshu 1, Hua Carroll 1, Ankur Sharma 1, Xiaobi Huang 1 and Nathalie Franchimont 1, 1Biogen, Cambridge, MA

    Background/Purpose: Background: BDCA2 is a plasmacytoid dendritic cell (pDC)-specific receptor that, when ligated inhibits the production of inflammatory mediators and Type I Interferon (INF), a…
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