Abstracts tagged "phagocytosis and tocilizumab"

Abstract Number: 1518 • 2014 ACR/ARHP Annual Meeting
Disentangling the Effects of Tocilizumab on Neutrophil Survival and Function
Timo Gaber^1,2,3, Martin Hahne⁴, Cindy Strehl², Paula Hoff¹, Yvonne Doerffel⁵, Eugen Feist¹, Gerd Burmester¹ and Frank Buttgereit⁶, ¹Department of Rheumatology and Clinical Immunology, Charité University Medicine, Berlin, Germany, ²German Rheumatism Research Center (DRFZ), Berlin, Germany, ³Berlin-Brandenburg Center of Regenerative Therapies (BCRT), Berlin, Germany, ⁴Berlin-Brandenburg School of Regenerative Therapies (BSRT), Berlin, Germany, ⁵Department of Gastroenterology and Hepatology, Charité University Medicine, Berlin, Germany, ⁶Charité University Hospital, Berlin, Germany
Background/Purpose The synovial tissue in rheumatoid arthritis (RA) represents a hypoxic environment with up-regulated pro-inflammatory cytokines and cellular infiltrates including neutrophils. Tocilizumab, a humanized IgG1…

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Abstracts tagged "phagocytosis and tocilizumab"

Disentangling the Effects of Tocilizumab on Neutrophil Survival and Function