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Abstracts tagged "pediatric rheumatology and therapy"

  • Abstract Number: 31 • 2017 Pediatric Rheumatology Symposium

    Predicting therapy response to IL-1 blockade in systemic JIA: a biomarker search

    Nienke M. ter Haar1, Rianne C. Scholman1, Wilco de Jager2, Nadia Ryter3, Ariane de Ganck4, Dirk Foell5, Sytze de Roock6 and Bas Vastert7, 1Laboratory for Translational Immunology, University Medical Center Utrecht, Utrecht, Netherlands, 2Dept Immunology, UMC Utrecht, Utrecht, Netherlands, 3BÜHLMANN Laboratories AG, Basel, Switzerland, 4Biogazelle NV, Zwijnaarde, Belgium, 5Pediatric Rheumatology and Immunology, University of Muenster, Muenster, Germany, 6Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht, Netherlands, 7Division of Pediatric Rheumatology, University Medical Center Utrecht, Utrecht, Netherlands

    Background/Purpose: Systemic onset juvenile idiopathic arthritis (sJIA) is an autoinflammatory disease, characterized by fever, rash and arthritis. The IL-1 and IL-6 pathway are crucial in…
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