Abstracts tagged "patient outcomes and rheumatoid arthritis (RA)"

Abstract Number: 1566 • 2015 ACR/ARHP Annual Meeting
The Impact of Severe Extra-Articular Manifestations and Patient Reported Outcome Measures on Cardiovascular Disease in Rheumatoid Arthritis
Lisa Theander¹, Jan-Åke Nilsson¹, Minna Willim^1,2, Britt-Marie Nyhäll-Wåhlin^1,3, Lennart T.H. Jacobsson^1,4 and Carl Turesson^1,5, ¹Rheumatology, Department of Clinical Sciences, Malmö, Lund University, Malmö, Sweden, ²Department of Rheumatology, Skåne University Hospital, Malmö, Sweden, ³Department of Rheumatology, Falun Hospital, Falun, Sweden, ⁴Department of Rheumatology and Inflammation Research, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden, ⁵Lund University, Rheumatology, Dept. of Clinical Sciences,, Malmö, Sweden
Background/Purpose: Rheumatoid arthritis (RA) is associated with increased risk of cardiovascular disease (CVD). Disease severity, including extra-articular rheumatoid arthritis (ExRA) manifestations, has previously been demonstrated…
Abstract Number: 2545 • 2015 ACR/ARHP Annual Meeting
Psychometric Testing of the Valued Life Activities Questionnaire in People with Rheumatoid Arthritis in the UK: Rasch Analysis
Yeliz Prior¹, Alan Tennant² and Alison Hammond³, ¹Centre for Health Sciences, University of Salford, Greater Manchester, United Kingdom, ²Human Functioning Sciences, ICF Unit, Swiss Paraplegic Research, Nottwil, Switzerland, ³Centre for Health Sport & Rehabilitation Research, University of Salford, Salford, United Kingdom
Background/Purpose: Developed in the USA, the Valued Life Activities Scale (VLAs) measures participation in daily activities. We have linguistically and culturally adopted the VLAs 33…
Abstract Number: 2613 • 2015 ACR/ARHP Annual Meeting
Patient Reported Physical Capacity Correlates with Phenylalanine Serum Levels in Patients with Early Untreated Rheumatoid Arthritis
Aulikki Kononoff¹, Leena Arstila^1,2, Hannu Kautiainen^3,4, Pia Elfving¹, Elina Savolainen⁵, Helena Niinisalo^6,7 and Oili Kaipiainen-Seppanen¹, ¹Department of Medicine, Kuopio University Hospital, Kuopio, Finland, ²Iisalmi Hospital, Iisalmi, Finland, ³Unit of Primary Health Care, Kuopio University Hospital, Kuopio, Finland, ⁴Unit of Primary Health Care, Helsinki University Central Hospital, Helsinki, Finland, ⁵Kuopio Municipal Hospital, Kuopio, Finland, ⁶Suonenjoki Health Center, Suonenjoki, Finland, ⁷Varkaus Hospital, Varkaus, Finland
Background/Purpose: Lipolysis is increased in rheumatoid arthritis (RA), and lipid-induced insulin resistance coincides with anabolic resistance. Ability to maintain skeletal muscle mass is impaired in…
Abstract Number: 2683 • 2015 ACR/ARHP Annual Meeting
Contribution of Subjective Patient Reported Components of Disease Activity Scores Differs in Disease Activity Measures and Their Changes over Time Are Closely Associated with Objective Measures
Yong Gil Hwang¹, Juan (June) Feng², Heather Eng², Jason Lyons², Anthony Fabio³ and Larry W. Moreland⁴, ¹Department of Medicine, University of Pittsburgh, Pittsburgh, PA, ²Epidemiology Data Center, University of Pittsburgh, Graduate School of Public Health, Pittsburgh, PA, ³Department Of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, ⁴Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: Patient reported measures are influenced by many non-rheumatoid arthritis (RA) factors and they are reflected variably among various composite disease activity scores (DAS). We…
Abstract Number: 425 • 2014 ACR/ARHP Annual Meeting
Beyond Disease Activity: Patient Global Scores Also Reflect Treatment Expectations and Emotional Reactions to Living with Rheumatoid Arthritis
Susan J. Bartlett¹, Maria Celia Bazan Bardales² and Ines Colmegna³, ¹Division of Rheumatology, Johns Hopkins University, Baltimore, MD, ²Rheumatology, McGill University, Montreal, QC, Canada, ³Rheumatology, McGill University - Royal Victoria Hospital, Montreal, QC, Canada
Background/Purpose: Illness perceptions (IP) are the beliefs and expectations that an individual has about medical conditions. IP have been found to cluster around five coherent…
Abstract Number: 416 • 2014 ACR/ARHP Annual Meeting
Using Patient Reported Outcome Measures to Classify Disease Activity States in Rheumatoid Arthritis: A Comparison of Patient-Derived Versions of Clinical Disease Activity Index (CDAI), Simplified Disease Activity Index (SDAI) and Disease Activity Score 28 (DAS28)
Erin Carruthers¹, Noura AL Osaimi², Charles H Goldsmith³, Paul Adam⁴ and Diane Lacaille⁵, ¹Arthritis Research Centre of Canada, Richmond, BC, Canada, ²Rheumatology, University of Ottawa, Ottawa, ON, Canada, ³Health Sciences, Simon Fraser University, Burnaby, BC, Canada, ⁴Mary Pack Arthritis Centre, Vancouver, BC, Canada, ⁵Medicine, University of British Columbia, Vancouver, BC, Canada
Background/PurposeIn RA the target for treatment is clinical remission or minimal disease activity. Patient self- monitoring of disease activity may enhance treatment by providing early…
Abstract Number: 384 • 2014 ACR/ARHP Annual Meeting
Using Patient Reported Outcome Measures to Classify Disease Activity States in Rheumatoid Arthritis: A Comparison of Patient Activity Score (PAS) and Routine Assessment of Patient Index Data (RAPID)
Erin Carruthers¹, Noura AL Osaimi², Charles H Goldsmith³, Paul Adam⁴ and Diane Lacaille⁵, ¹Arthritis Research Centre of Canada, Richmond, BC, Canada, ²Rheumatology, University of Ottawa, Ottawa, ON, Canada, ³Health Sciences, Simon Fraser University, Burnaby, BC, Canada, ⁴Mary Pack Arthritis Centre, Vancouver, BC, Canada, ⁵Arthritis Research Centre of Canada, Vancouver, BC, Canada
Background/PurposeIn RA the target for treatment is clinical remission or minimal disease activity. Patient involvement in monitoring their disease activity could enhance treatment by providing…
Abstract Number: 2048 • 2014 ACR/ARHP Annual Meeting
Disability in Discretionary Valued Life Activities and Self-Efficacy Explain a Significant Portion of RA Patients’ Global Assessments
Patricia P. Katz¹, Jennifer Barton¹, Chris Tonner², Jinoos Yazdany¹, Mary Margaretten¹, Gabriela Schmajuk¹ and Ed Yelin¹, ¹Medicine, University of California, San Francisco, San Francisco, CA, ²3333 California Street, Box 09, University of California, San Francisco, San Francisco, CA
Background/Purpose . Patient global assessments are components of RA disease activity calculations. Patient global assessments, however, do not consistently agree with physician assessments. This discrepancy…
Abstract Number: 1380 • 2014 ACR/ARHP Annual Meeting
Patient Global Impression of Change for Patient Reported Outcomes in Rheumatoid Arthritis: Impact of Comorbidities
Pankaj Bansal¹, Aneet Kaur², Horace Spencer² and Nasim A. Khan³, ¹Rheumatology/ Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, ²University of Arkansas for Medical Sciences, Little Rock, AR, ³Rheumatology, University of Arkansas for Medical Sciences and Central Arkansas Veterans Healthcare System, Little Rock, AR
Background/Purpose: Understanding patient’s perspective of minimally clinically important difference (MCID) in health (or disease) status is important to improve patient-centered clinical care and planning and…
Abstract Number: 492 • 2014 ACR/ARHP Annual Meeting
Patient-Reported Outcomes from a Canadian Study of Patients Taking Methotrexate and Etanercept
J. Carter Thorne¹, Edward C. Keystone², Janet E. Pope³, Melanie Poulin-Costello⁴, Krystene Phan-Chronis⁵ and Boulos Haraoui⁶, ¹Southlake Regional Health Centre, Newmarket, ON, Canada, ²Medicine, University of Toronto, Toronto, ON, Canada, ³St Joseph Health Care, London, ON, Canada, ⁴Biostatistics, Amgen Canada Inc., Mississauga, ON, Canada, ⁵Amgen Canada Inc., Mississauga, ON, Canada, ⁶Rheumatology, Institut de rhumatologie de Montréal (IRM), Montréal, QC, Canada
Background/Purpose: The Canadian Methotrexate and Etanercept Outcome Study (CAMEO) evaluated etanercept (ETN) monotherapy vs ETN plus methotrexate (MTX) in biologic-naïve patients with rheumatoid arthritis…
Abstract Number: 2867 • 2013 ACR/ARHP Annual Meeting
Using Patient Reported Outcomes Measurement Information System Instruments To Identify Disease Flares In People With Rheumatoid Arthritis
Susan J. Bartlett^1,2, Ana-Maria Orbai³, Trisha Duncan³ and Clifton O. Bingham III³, ¹Clinical Epidemiology, McGill University, Montreal, QC, Canada, ²Division of Rheumatology, Johns Hopkins School of Medicine, Baltimore, MD, ³Rheumatology, Johns Hopkins University, Baltimore, MD
Background/Purpose: Rheumatoid arthritis (RA) is associated with unpredictable episodes of disease worsening that may prompt consideration of treatment change. Core RA Flare domains have been…
Abstract Number: 2869 • 2013 ACR/ARHP Annual Meeting
Changes In Patient-Reported Joint Counts and Composite Indices Can Identify Flare Of Disease Activity In Recent Onset Rheumatoid Arthritis
Karen Visser¹, Susan J. Bartlett^2,3, Clifton O. Bingham III⁴, Ernest Choy⁵, Daming Lin⁶, Juan Xiong⁷, Gilles Boire⁸, Boulos Haraoui⁹, Carol A. Hitchon¹⁰, Edward Keystone¹¹, Janet E. Pope¹², J. Carter Thorne¹³, Diane Tin¹⁴ and Vivian P. Bykerk¹⁵, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Clinical Epidemiology, McGill University, Montreal, QC, Canada, ³Division of Rheumatology, Johns Hopkins University, Baltimore, MD, ⁴Division of Rheumatology, Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ⁵Section of Rheumatology, Cardiff University, Institute of Infection and Immunity, Cardiff, United Kingdom, ⁶Rheumatology, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, ⁷Mount Sinai Hospital, Toronto, ON, Canada, ⁸Rheumatology Division, Centre Hospitalier Universitaire de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, Canada, ⁹Department of Medicine, Centre Hospitalier de l’Université de Montréal, Montréal, QC, Canada, ¹⁰Rheumatology, University of Manitoba, Winnipeg, MB, Canada, ¹¹Rebecca MacDonald Centre for Arthritis and Autoimmune Disease, University of Toronto, Toronto, ON, Canada, ¹²St Joseph Health Care, London, ON, Canada, ¹³Southlake Regional Health Centre, Newmarket, ON, Canada, ¹⁴The Arthritis Program, Southlake Regional Health Centre, Newmarket, ON, Canada, ¹⁵Rheumatology, Hospital for Special Surgery, Weill Cornell Medical College, New York, NY
Background/Purpose: Patient-reported joint counts (JCs) have been identified as core domains for assessment of flare in rheumatoid arthritis (RA).[1] To assess the responsiveness and discriminative…
Abstract Number: 2285 • 2013 ACR/ARHP Annual Meeting
Correlation Of Individual Health Assessment Questionnaire (HAQ) Questions With Outcome Measures In Rheumatoid Arthritis: Implications For Instrument Reduction
J. Carter Thorne¹, Majed M. Khraishi², Boulos Haraoui^3,4, Jude F. Rodrigues⁵, Algis Jovaisas⁶, Denis Choquette³, Sanjay Dixit⁷, Dalton E. Sholter⁸, Philip Baer⁹, Maqbool K. Sheriff¹⁰, Emmanouil Rampakakis^11,12, John S. Sampalis^11,12, Francois Nantel¹³, Allen J. Lehman¹⁴, May Shawi¹⁵ and Susan M. Otawa¹⁴, ¹Southlake Regional Health Centre, Newmarket, ON, Canada, ²Nexus Clinical Research, St John's, NF, Canada, ³Rheumatology, Institut de rhumatologie de Montréal (IRM), Montréal, QC, Canada, ⁴Department of Medicine, Centre Hospitalier de l’Université de Montréal, Montréal, QC, Canada, ⁵Rheumatology, Windsor, ON, Canada, ⁶Division of Rheumatology, University of Ottawa, Ottawa, ON, Canada, ⁷McMaster University, Hamilton, ON, Canada, ⁸Rheumatology Associates, Edmonton, AB, Canada, ⁹Private Practice, Scarborough, ON, Canada, ¹⁰Nanaimo Regional General Hospital, Nanaimo, BC, Canada, ¹¹JSS Medical Research, Montreal, QC, Canada, ¹²Jewish General Hospital, McGill University, Montreal, QC, Canada, ¹³Janssen Inc., Toronto, ON, Canada, ¹⁴Medical Affairs, Janssen Inc., Toronto, ON, Canada, ¹⁵Medical Affairs, Janssen Canada Inc, Toronto, ON, Canada
Background/Purpose: Despite the importance of the Health Assessment Questionnaire (HAQ) in assessing patient-reported functional status, it was originally developed primarily for research studies. As a…
Abstract Number: 2286 • 2013 ACR/ARHP Annual Meeting
Reliability and Smallest Detectable Difference Of The Patient Global Assessment, Pain and Fatigue In Rheumatoid Arthritis Patients
Paul Studenic¹, Josef S. Smolen^2,3 and Daniel Aletaha⁴, ¹Department of Internal Medicine 3, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, ²PsAID taskforce, EULAR, Zurich, Switzerland, ³2nd Department of Medicine, Krankenhaus Lainz, Vienna, Austria, ⁴Department of Internal Medicine III, Division of Rheumatology, Medical University Vienna, Vienna, Austria
Background/Purpose: Patient reported outcomes (PRO) represent an important part of outcomes assessment in rheumatoid arthritis (RA) patients. The Patient Global Assessment (PGA) is an essential…
Abstract Number: 2252 • 2013 ACR/ARHP Annual Meeting
Assessment Of Rheumatoid Arthritis Disease Activity By Patients and Physicians: Do Physicians Detect Improvement Before The Patient Does?
William G. Bensen¹, J. Carter Thorne², Philip Baer³, Andrew Chow⁴, Regan Arendse⁵, Isabelle Fortin⁶, Milton F. Baker⁷, Boulos Haraoui^8,9, Algis Jovaisas¹⁰, John S. Sampalis^11,12, Emmanouil Rampakakis^11,12, Allen J. Lehman¹³, Francois Nantel¹⁴, May Shawi¹⁵ and Susan M. Otawa¹³, ¹Department of Medicine, Division of Rheumatology, Clinical Professor, McMaster University, Hamilton, ON, Canada, ²Southlake Regional Health Centre, Newmarket, ON, Canada, ³Private Practice, Scarborough, ON, Canada, ⁴University of Toronto, McMaster University, Credit Valley Rheumatology, Mississauga, ON, Canada, ⁵University of Saskatchewan, Saskatoon, SK, Canada, ⁶Centre de rhumatologie de l'est du Québec (CREQ), Rimouski, QC, Canada, ⁷University of Victoria, Victoria, BC, Canada, ⁸Rheumatology, Institut de rhumatologie de Montréal (IRM), Montréal, QC, Canada, ⁹Department of Medicine, Centre Hospitalier de l’Université de Montréal, Montréal, QC, Canada, ¹⁰Division of Rheumatology, University of Ottawa, Ottawa, ON, Canada, ¹¹JSS Medical Research, Montreal, QC, Canada, ¹²Jewish General Hospital, McGill University, Montreal, QC, Canada, ¹³Medical Affairs, Janssen Inc., Toronto, ON, Canada, ¹⁴Janssen Inc., Toronto, ON, Canada, ¹⁵Medical Affairs, Janssen Canada Inc, Toronto, ON, Canada
Background/Purpose: Patient (PtGA) and physician (MDGA) global assessment of disease activity measure the same construct from two different perspectives. The objective of this study was…

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