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Abstracts tagged "pathogenesis and vasculitis"

  • Abstract Number: 906 • ACR/ARHP Annual Meeting 2018

    Defining the Gut Microbiome in Patients with ANCA-Associated Vasculitis

    Catherine E. Najem1, Jung-Jin Lee2, Ceylan Tanes2, Antoine G. Sreih1, Rennie L. Rhee1, Abdallah Geara3, Hongzhe Li4, Kyle Bittinger2, James D. Lewis5 and Peter A. Merkel4,6, 1Rheumatology, Division of Rheumatology, University of Pennsylvania, Philadelphia, PA, 2Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA, 3Division of Nephrology and Hypertension, University of Pennsylvania, Philadelphia, PA, 4Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Philadelphia, PA, 5Division of Gastroenterology, University of Pennsylvania, Philadelphia, PA, 6Division of Rheumatology, University of Pennsylvania, Philadelphia, PA

    Background/Purpose:Although a link between gut microbiome and autoimmune diseases has been suggested, there is a gap in the understanding of the gut microbiome in ANCA-associated…
  • Abstract Number: 2728 • ACR/ARHP Annual Meeting 2017

    Serum Levels of Interleukin-36 Receptor Antagonist in Behçet’s Patients

    Pelin Ünsal1, Pamir Cerci2, Şükrü Alper Açıkgöz2, Göksal Keskin2 and Ümit Ölmez2, 1Ankara University School of Medicine, Ankara, Turkey, 2Immunology and Allergy, Ankara University School of Medicine, Ankara, Turkey

    Background/Purpose: Behcet's disease (BD) is a systemic vasculitis disorder of unknown etiology with recurrent exacerbations and remissions. The etiopathogenesis of the disease is still unclear.…
  • Abstract Number: 1937 • ACR/ARHP Annual Meeting 2016

    Analysis of Innate and Adaptive Immune Responses in Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss)

    Jeremie Dion1,2, Jonathan London2,3, Benjamin Chaigne2,4, Nicolas Dumoitier2, Bertrand Dunogué5, Pascal Cohen3, Matthieu Groh4, Claire Le Jeunne4, Luc Mouthon2,5 and Benjamin Terrier2,5, 1Internal medicine, National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France, 2INSERM U1016, Institut Cochin, Equipe Neutrophiles et Vascularites, Paris, France, 3Internal Medecine, National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France, 4National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France, 5Internal Medicine, National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France

    Background/Purpose: Eosinophilic granulomatosis with polyangiitis (EGPA, formerly called Churg-Strauss syndrome) belongs to ANCA-associated vasculitis and is characterized by late onset asthma, blood and tissue eosinophilia…
  • Abstract Number: 1992 • ACR/ARHP Annual Meeting 2015

    Plasma Endothelin-1 Parallels the Vasoconstriction Phase in Reversible Cerebral Vasoconstriction Syndrome

    Seby John1, Leonard H. Calabrese2, Juan J. Maya3, Alex Massiello4, Ken Uchino1, Serpil Erzurum5, Allison Janocha5 and Rula A Hajj-Ali6, 1Cerebrovascular Center, Cleveland Clinic Foundation, Cleveland, OH, 2Rheumatic & Immunologic Dis, Cleveland Clinic Foundation, Cleveland, OH, 3Internal Medicine, Cleveland Clinic, Cleveland, OH, 4Rheumatology, Cleveland Clinic, Cleveland, OH, 5Cleveland Clinic, Cleveland, OH, 6Rheumatic and Immunologic Dis, Cleveland Clinic, Cleveland, OH

    Plasma Endothelin-1 parallels the vasoconstriction phase in Reversible Cerebral Vasoconstriction SyndromeBackground/Purpose: Cerebral vasoconstriction is thought to be the underlying pathogenetic mechanism of Reversible Cerebral Vasoconstriction…

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