Abstracts tagged "pathogenesis and vasculitis"

Abstract Number: 906 • 2018 ACR/ARHP Annual Meeting
Defining the Gut Microbiome in Patients with ANCA-Associated Vasculitis
Catherine E. Najem¹, Jung-Jin Lee², Ceylan Tanes², Antoine G. Sreih¹, Rennie L. Rhee¹, Abdallah Geara³, Hongzhe Li⁴, Kyle Bittinger², James D. Lewis⁵ and Peter A. Merkel^4,6, ¹Rheumatology, Division of Rheumatology, University of Pennsylvania, Philadelphia, PA, ²Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA, ³Division of Nephrology and Hypertension, University of Pennsylvania, Philadelphia, PA, ⁴Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Philadelphia, PA, ⁵Division of Gastroenterology, University of Pennsylvania, Philadelphia, PA, ⁶Division of Rheumatology, University of Pennsylvania, Philadelphia, PA
Background/Purpose:Although a link between gut microbiome and autoimmune diseases has been suggested, there is a gap in the understanding of the gut microbiome in ANCA-associated…
Abstract Number: 2728 • 2017 ACR/ARHP Annual Meeting
Serum Levels of Interleukin-36 Receptor Antagonist in Behçet’s Patients
Pelin Ünsal¹, Pamir Cerci², Şükrü Alper Açıkgöz², Göksal Keskin² and Ümit Ölmez², ¹Ankara University School of Medicine, Ankara, Turkey, ²Immunology and Allergy, Ankara University School of Medicine, Ankara, Turkey
Background/Purpose: Behcet's disease (BD) is a systemic vasculitis disorder of unknown etiology with recurrent exacerbations and remissions. The etiopathogenesis of the disease is still unclear.…
Abstract Number: 1937 • 2016 ACR/ARHP Annual Meeting
Analysis of Innate and Adaptive Immune Responses in Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss)
Jeremie Dion^1,2, Jonathan London^2,3, Benjamin Chaigne^2,4, Nicolas Dumoitier², Bertrand Dunogué⁵, Pascal Cohen³, Matthieu Groh⁴, Claire Le Jeunne⁴, Luc Mouthon^2,5 and Benjamin Terrier^2,5, ¹Internal medicine, National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France, ²INSERM U1016, Institut Cochin, Equipe Neutrophiles et Vascularites, Paris, France, ³Internal Medecine, National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France, ⁴National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France, ⁵Internal Medicine, National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France
Background/Purpose: Eosinophilic granulomatosis with polyangiitis (EGPA, formerly called Churg-Strauss syndrome) belongs to ANCA-associated vasculitis and is characterized by late onset asthma, blood and tissue eosinophilia…
Abstract Number: 1992 • 2015 ACR/ARHP Annual Meeting
Plasma Endothelin-1 Parallels the Vasoconstriction Phase in Reversible Cerebral Vasoconstriction Syndrome
Seby John¹, Leonard H. Calabrese², Juan J. Maya³, Alex Massiello⁴, Ken Uchino¹, Serpil Erzurum⁵, Allison Janocha⁵ and Rula A Hajj-Ali⁶, ¹Cerebrovascular Center, Cleveland Clinic Foundation, Cleveland, OH, ²Rheumatic & Immunologic Dis, Cleveland Clinic Foundation, Cleveland, OH, ³Internal Medicine, Cleveland Clinic, Cleveland, OH, ⁴Rheumatology, Cleveland Clinic, Cleveland, OH, ⁵Cleveland Clinic, Cleveland, OH, ⁶Rheumatic and Immunologic Dis, Cleveland Clinic, Cleveland, OH
Plasma Endothelin-1 parallels the vasoconstriction phase in Reversible Cerebral Vasoconstriction SyndromeBackground/Purpose: Cerebral vasoconstriction is thought to be the underlying pathogenetic mechanism of Reversible Cerebral Vasoconstriction…

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