Abstracts tagged "pain"

Abstract Number: 0592 • ACR Convergence 2024
Sustained Improvements with Bimekizumab in Patient-Reported Symptoms of Axial Spondyloarthritis: 2-Year Results from Two Phase 3 Studies
Helena Marzo-Ortega¹, Philip Mease², Maxime Dougados³, Maureen Dubreuil⁴, Marina Magrey⁵, Martin Rudwaleit⁶, Maria Antonietta D'Agostino⁷, Christine de la Loge⁸, Ute Massow⁹, Vanessa Taieb¹⁰, Diana Voiniciuc¹¹ and Atul Deodhar¹², ¹NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ²Swedish Medical Center/Providence St. Joseph Health; University of Washington School of Medicine, Seattle, WA, ³Rheumatology Department, Cochin Hospital and Clinical Epidemiology and Biostatistics, University of Paris, INSERM (U1153), Paris, France, ⁴Section of Rheumatology, Boston University School of Medicine, Boston, MA, ⁵Case Western Reserve University School of Medicine/University Hospitals, Richfield, OH, ⁶University of Bielefeld, Klinikum Bielefeld, Bielefeld, Germany, ⁷Division of Rheumatology, Fondazione Policlinico Universitario Agostino Gemelli IRCSS, Università Cattolica del Sacro Cuore, Rome, Italy, ⁸UCB Pharma, Brussels, Belgium, ⁹UCB Pharma, Monheim am Rhein, Germany, ¹⁰UCB Pharma, Colombes, France, ¹¹UCB Pharma, Slough, United Kingdom, ¹²Division of Arthritis and Rheumatic Diseases, Oregon Health & Science University, Portland, OR
Background/Purpose: In the phase 3 studies, BE MOBILE 1 and 2, bimekizumab (BKZ), a monoclonal IgG1 antibody that selectively inhibits interleukin (IL)-17F in addition to…
Abstract Number: 1185 • ACR Convergence 2024
Walking Is Associated with Less Knee Pain: A Cross-sectional Study from the Osteoarthritis Initiative
Sydney Tran¹, Jeffrey Driban², Timothy McAlindon³, Andrea Kriska⁴, Bonny Rockette-Wagner⁴, Charles Eaton⁵, Marc Hochberg⁶, Kent Kwoh⁷, Michael Nevitt⁸ and Grace Lo⁹, ¹Baylor College of Medicine, Houston, ²University of Massachusetts Chan Medical School, Worcester, MA, ³University of Massachusetts Chan Medical School, Worcester, ⁴University of Pittsburgh, Pittsburgh, PA, ⁵Warren Alpert Medical School of Brown University, Providence, RI, ⁶University of Maryland School of Medicine, Cambridge, MD, ⁷University of Arizona, Tucson, AZ, ⁸University of California, San Francisco, San Francisco, CA, ⁹Baylor College of Medicine / MEDVAMC, Houston, TX
Background/Purpose: Osteoarthritis (OA) is the most common form of arthritis, with the knee being the most common joint involved. Exercise is a leading non-pharmacological treatment…
Abstract Number: 1222 • ACR Convergence 2024
Large Language Model-driven Sentiment Analysis for Facilitating Fibromyalgia Diagnosis
Vincenzo Venerito and Florenzo Iannone, Rheumatology Unit- University of Bari "Aldo Moro", IT, Bari, Italy
Background/Purpose: Fibromyalgia (FM) is a complex disorder with widespread pain and emotional distress, posing diagnostic challenges. FM patients show altered cognitive and emotional processing, with…
Abstract Number: 1668 • ACR Convergence 2024
Association of Wearable-Sensor Derived Gait Measures with Widespread Pain over 2 Years: A Machine Learning Analysis in the Multicenter Osteoarthritis Study
Kathryn Bacon¹, David Felson², S. Reza Jafarzadeh³, Jeffrey Hausdorff⁴, Eran Gazi⁵, Neil Segal⁶, Cora Lewis⁷, Michael Nevitt⁸ and Deepak Kumar², ¹Boston University, Webster, NH, ²Boston University, Boston, MA, ³Boston University Chobanian & Avedisian School of Medicine, Boston, MA, ⁴Tel Aviv University, Tel Aviv, Israel, Tel Aviv, Israel, ⁵Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, ⁶University of Kansas, Kansas City, KS, ⁷University of Alabama at Birmingham, Birmingham, AL, ⁸University of California, San Francisco, San Francisco, CA
Background/Purpose: Gait patterns can put stress on the back and weight bearing joints and can even affect upper extremity joints. Walking involves muscle activation and…
Abstract Number: 2115 • ACR Convergence 2024
Clinical Impact of Acute Symptomatic Vertebral Fractures in the United States: An Observational Study
Neil Binkley¹, Michele McDermott², Eric Yeh², Joseph Lane³, Jolenta Cheung⁴, Mona Amet⁴ and Felicia Cosman⁵, ¹University of Wisconsin, Madison, ²Amgen Inc., Thousand Oaks, ³Hospital for Special Surgery, Weill Cornell Medical College, New York, NY, ⁴Adelphi Real World, Bollington, United Kingdom, ⁵Columbia University, College of Physicians and Surgeons, New York, NY
Background/Purpose: To characterize pain status (frequency, severity, persistency) and effect on activities of daily living (ADLs) in patients with symptomatic vertebral fractures (VF).Methods: This was…
Abstract Number: L19 • ACR Convergence 2023
A Phase 3 Study of Repeat Injection of TLC599 in Osteoarthritis of the Knee: Benefits to 52 Weeks
George Spencer-Green¹, David Hunter², Thomas Schnitzer³, Sheue-Fang Shih⁴, Tien-Tzu Tai⁴, Cathy Kao⁴ and Siao-Ning Huang⁴, ¹Taiwan Liposome Company, Cambridge, MA, ²Sydney Musculoskeletal Health, University of Sydney, St Leonards, New South Wales, Australia, ³Northwestern University Feinberg School of Medicine, Chicago, IL, ⁴Taiwan Liposome Company, Taipei, Taiwan (Republic of China)
Background/Purpose: In osteoarthritis (OA) of the knee, intraarticular injections of corticosteroids can relieve pain, reduce inflammation, and improve mobility, but the effect is not predictable,…
Abstract Number: 0150 • ACR Convergence 2023
Self-reported Levels of Physical Activity and the Association to Pain, Fatigue, Anxiety and Depression Among Patients with Idiopathic Inflammatory Myopathies
Kristofer Andreasson¹, Fabricio Espinosa-Ortega², Heléne Sandlund³ and Helene Alexanderson⁴, ¹Karolinska Institutet & Karolinska University Hospital, Stockholm, Sweden, ²Division of Rheumatology, Department of Medicine, Karolinska Institutet; Department of Gastroenterology, Dermatotology, Rhematology, Karolinska Universitetssjukhuset, Stockholm, Sweden, ³Karolinska University Hospital, Stockholm, Sweden, ⁴Karolinska Institutet, Stockholm, Sweden
Background/Purpose: Patients with inflammatory diseases such as rheumatoid arthritis exhibit reduced levels of physical activity (PA) compared to the normative population and suffer from anxiety…
Abstract Number: 0510 • ACR Convergence 2023
Bimekizumab Treatment Improved Key Patient-Reported Symptoms of Axial Spondyloarthritis Including Spinal Pain, Fatigue, and Morning Stiffness: 52-Week Results from Two Phase 3 Studies
Philip J. Mease¹, Maxime Dougados², Maureen Dubreuil³, Marina Nighat Magrey⁴, Helena Marzo-Ortega⁵, Martin Rudwaleit⁶, Christine de la Loge⁷, Carmen Fleurinck⁸, Ute Massow⁹, Vanessa Taieb¹⁰ and Atul Deodhar¹¹, ¹Swedish Medical Center/Providence St. Joseph Health and University of Washington School of Medicine, Seattle, WA, ²Department of Rheumatology, Hôpital Cochin, University of Paris Cité, Paris, France, ³Department of Rheumatology, Boston University School of Medicine, Milton, MA, ⁴Case Western Reserve University, University Hospitals, Cleveland, OH, ⁵NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ⁶University of Bielefeld, Klinikum Bielefeld, Bielefeld, Germany, ⁷UCB Pharma, Brussels, Belgium, ⁸UCB Pharma, Oosterzele, Belgium, ⁹UCB Pharma, Monheim am Rhein, Germany, ¹⁰UCB Pharma, Colombes, France, ¹¹Division of Arthritis and Rheumatic Disease, Oregon Health & Science University, Portland, OR
Background/Purpose: Bimekizumab (BKZ) is a monoclonal IgG1 antibody that selectively inhibits IL-17F in addition to IL-17A. In the phase 3 studies BE MOBILE 1 and…
Abstract Number: 1018 • ACR Convergence 2023
Recognizing Rural Healthcare Disparities in Pain Assessment for Autoimmune Rheumatologic Diseases
Lydia Yang¹, Bharat Kumar² and Melissa Swee¹, ¹University of Iowa Carver College of Medicine, Iowa City, IA, ²University of Iowa Hospitals and Clinics, Iowa City, IA
Background/Purpose: Pain is a common complaint seen in many autoimmune rheumatologic conditions, along with decreased function and decreased sense of well-being. Pain is a highly…
Abstract Number: 1427 • ACR Convergence 2023
Efficacy of Upadacitinib in Patients with Psoriatic Arthritis Stratified by Involvement of Weight-bearing Joint Regions: A Post Hoc Subgroup Analysis of the Phase 3, Randomized, SELECT-PsA 1 and SELECT-PsA 2 Trials
Kristi Mizelle¹, William R Tillett², Mira Ali³, Thomas Iyile³, Tianming Gao³, Arathi Setty³, Jessica A Walsh⁴ and Laura Coates⁵, ¹Tidewater Physicians Multispecialty Group, Newport News, VA, ²Department of Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, ³AbbVie, Inc., North Chicago, IL, ⁴Salt Lake City Veterans Affairs Health and University of Utah Health, Division of Rheumatology, Salt Lake City, UT, ⁵University of Oxford, Oxford, United Kingdom
Background/Purpose: Involvement of weight-bearing joints in patients with PsA can be associated with reduced activities of daily living and quality of life. Upadacitinib (UPA) is…
Abstract Number: 1830 • ACR Convergence 2023
Exploring Psychosocial Characteristics of Youth with Chronic Pain Across Gender Identities
Evan Mulvihill¹, Liam Courtney², Alora Rando¹ and Katherine Salamon³, ¹Nemours Children's Health, Wilmington, DE, ²Rowan-Virtua School of Osteopathic Medicine, Stratford, NJ, ³Nemours Children's Health, Wilmingon, DE
Background/Purpose: Pediatric chronic pain is a common, significant public health concern leading to decreased quality of life for youth and burden on the healthcare system1.…
Abstract Number: 1994 • ACR Convergence 2023
How Is Paracetamol Prescribed in Low Back Pain and Osteoarthritis in France? Paracetamol Prescription Patterns in the Real-World General Practice
Jasque Cittée¹, Pierre Lemire², Anna Annenkova³, Jean-Yves Milon³ and Serge Perrot⁴, ¹University Paris-Est Créteil Val de Marne Department of General Medicine, Paris, France, ²IQVIA, Paris, France, ³UPSA, Rueil-Malmaison, France, ⁴Cochin Hospital, Université Paris Cité, INSERM U987, Paris, France
Background/Purpose: Lower back pain (LBP) and osteoarthritis (OA) are the most frequent musculoskeletal disorders in the general population significantly impacting patients' quality of life. An…
Abstract Number: 0153 • ACR Convergence 2023
Diminished Vibration Perception and Greater Pressure Pain Sensitivity Are Associated with Worse Knee Osteoarthritis Outcomes Across Sex and Race
Chris Lane¹, Louise Thoma², Carolina Alvarez³, Deborah Givens⁴, Amanda Nelson⁴, Adam Goode⁵, Kharma Foucher⁶ and Yvonne Golightly⁷, ¹UNC Chapel Hill, Chapel Hill, NC, ²University of North Carolina, Chapel Hill, NC, ³University of North Carolina at Chapel Hill, Miami, FL, ⁴University of North Carolina at Chapel Hill, Chapel Hill, NC, ⁵Duke University, Durham, NC, ⁶University of Illinois at Chicago, Chicago, IL, ⁷University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Sex and race differences have been observed in clinical outcomes such as patient-reported pain and function in adults with knee OA. However, few studies…
Abstract Number: 0527 • ACR Convergence 2023
Bimekizumab Treatment Impact on Pain and Fatigue in Patients with Active Psoriatic Arthritis Who Were Biologic DMARD‑Naïve or Had Inadequate Response or Intolerance to TNF-α Inhibitors: 1-Year Results from Two Phase 3 Studies
M. Elaine Husni¹, Philip J. Mease², Joseph Merola³, Frank Behrens⁴, Ennio G Favalli⁵, Dennis McGonagle⁶, William R Tillett⁷, Shigeyoshi Tsuji⁸, Barbara Ink⁹, Rajan Bajracharya⁹, Jérémy Lambert¹⁰, Jason Coarse¹¹ and Laure Gossec¹², ¹Cleveland Clinic / Department of Rheumatic and Immunologic Diseases, Cleveland, OH, ²Swedish Medical Center/Providence St. Joseph Health and University of Washington School of Medicine, Seattle, WA, ³Harvard Medical School, Brigham and Women's Hospital, Newton, MA, ⁴Goethe University, Division of Rheumatology, University Hospital and Fraunhofer Institute for Translational Medicine & Pharmacology, Frankfurt, Germany, ⁵ASST Gaetano Pini-CTO, University of Milan, Department of Rheumatology, Milan, Italy, ⁶Leeds Biomedical Research Centre, University of Leeds, Leeds, United Kingdom, ⁷Department of Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, ⁸Nippon Life Hospital, Osaka, Japan, ⁹UCB Pharma, Slough, United Kingdom, ¹⁰UCB Pharma, Irigny, France, ¹¹UCB Pharma, Morrisville, NC, ¹²Sorbonne Université and Pitié Salpêtrière Hospital, Paris, France
Background/Purpose: Pain and fatigue have been identified by patients (pts) as key features of PsA, driving the impact on their health-related quality of life.1 Bimekizumab…
Abstract Number: 1039 • ACR Convergence 2023
Cross-Sectional Associations of Ultrasound Features with Symptom Outcomes at the Knee: A Community-based Study
Katherine Yates¹, Carolina Alvarez², Todd Schwartz³, Serena Savage-Guin⁴, Jordan Renner⁴, Catherine Bakewell⁵, Minna Kohler⁶, Janice Lin⁷, Jonathan Samuels⁸ and Amanda Nelson⁴, ¹University of North Carolina Medical Center, Chapel Hill, NC, ²University of North Carolina at Chapel Hill, Miami, FL, ³University of North Carolina-Chapel Hill, Chapel Hill, NC, ⁴University of North Carolina at Chapel Hill, Chapel Hill, NC, ⁵Intermountain Healthcare, Salt Lake City, UT, ⁶Massachusetts General Hospital, Harvard Medical School, Boston, MA, ⁷Stanford University, Palo Alto, CA, ⁸NYU Langone, Rye Brook, NY
Background/Purpose: Ultrasound (US) allows for visualization of many features of knee osteoarthritis (KOA) including osteophytes, meniscal extrusion, synovitis, and articular cartilage damage. Additionally, US is…

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