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Abstracts tagged "pain"

  • Abstract Number: 1240 • ACR Convergence 2025

    Serum Olink Proteomics Identifies Novel Mediators of Pain in Lupus Nephritis Patients Without Extrarenal Clinical Activity

    Sarah Keegan1, Philip Carlucci2, Peter Izmirly3, Erin Carter4, Sanchit Sanyal5, Brooke Cohen6, Jasmine Shwetar7, Katie Preisinger8, Devyn Zaminski6, Kristina Deonaraine6, Mala Masson9, Andrea Fava10, Judith James11, Rufei Lu11, Wade DeJager12, Chaim Putterman13, Michael Belmont14, Richard Furie15, Maria Dall'Era16, Diane Kamen17, Kenneth Kalunian18, Jennifer Anolik19, David Wofsy20, Jennifer Barnas21, Nir Hacohen22, Robert Clancy23, Joel Guthridge11, Brad Rovin24, Michelle Petri25, Jill Buyon3 and Kelly Ruggles26, 1NYU Langone, New York, 2New York University School of Medicine, New York, NY, 3NYU Grossman School of Medicine, New York, NY, 4New York University Grossman School of Medicine, New York, NY, 5Johns Hopkins University School of Medicine, Baltimore, MD, 6NYU Langone, NYC, 7New York University School of Medicine, Department of Medicine, New York, 8NYU Langone, NYU Langone, 9NYU Langone Medical Center- Division of Rheumatology, New York, NY, 10Johns Hopkins University, Baltimore, MD, 11Oklahoma Medical Research Foundation, Oklahoma City, OK, 12Oklahoma Medical Research Foundation, Oklahoma City, 13Albert Einstein College of Medicine, Safed, Israel, 14NYU Langone Health, New York, NY, 15Division of Rheumatology, Northwell Health, Great Neck, NY, 16Division of Rheumatology, University of California, San Francisco, CA, 17Medical University of South Carolina, Johns Island, SC, 18UC San Diego, La Jolla, CA, 19University of Rochester Medical Center, Rochester, NY, 20University of California San Francisco, SF, CA, 21University of Rochester, Rochester, NY, 22Broad Institute of MIT Harvard, Cambridge, MA, 23Columbia University, New York, NY, 24The Ohio State University, Columbus, OH, 25Johns Hopkins University School of Medicine, Timonium, MD, 26NYU Grossman School of Medicine, Brooklyn, NY

    Background/Purpose: For patients with lupus nephritis, active disease can be solely renal or include a range of extrarenal signs, such as arthritis or serositis, that…
  • Abstract Number: 1223 • ACR Convergence 2025

    Pain and Fibromyalgia Across Autoimmune and Inflammatory Diseases in the AMP AIM Cohort

    Alexis Ogdie1, Astrid Rasmussen2, Dana Orange3, Michelle Petri4, Caroline Shiboski5, Rebecca Haberman6, Mala Masson7, Daniel Goldman4, Peter Izmirly8, Brooke Cohen9, Jennifer Seifert10, Jennifer Anolik11, Wade DeJager12, Alan Baer13, Jill Buyon14 and Yvonne Lee15, 1Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Wilmington, DE, 2Oklahoma Medical Research Foundation, Oklahoma City, OK, 3The Rockefeller University, New York, NY, 4Johns Hopkins University School of Medicine, Timonium, MD, 5University of California San Francisco, San Francisco, CA, 6NYU Langone Health, New York, NY, 7NYU Langone Medical Center- Division of Rheumatology, New York, NY, 8New York University Grossman School of Medicine, New York, NY, 9Yale Physician Associate Program, New Haven, CT, 10University of Colorado and Oklahoma Medical Research Foundation, Aurora, CO, 11University of Rochester Medical Center, Rochester, NY, 12Oklahoma Medical Research Foundation, Oklahoma City, 13Johns Hopkins University School of Medicine, Baltimore, MD, 14NYU Grossman School of Medicine, New York, NY, 15Northwestern University, Chicago, IL

    Background/Purpose: The Accelerating Medicines Partnership Autoimmune and Immune-Mediated Diseases (AMP AIM) network seeks to understand the cellular and molecular interactions that lead to inflammation and…
  • Abstract Number: 0530 • ACR Convergence 2025

    Evaluating ChatGPT’s Performance in Diagnosing Low Back Pain: A Comparison with Clinicians and Impact of Prompted Specialties

    Annika Nack1, Xabier Michelena Vegas2, Pol Maymó-Paituvi3, Cristina Calomarde-Gómez4, david lobo5, Asier García-Alija6, Raquel Ugena-García4, Maria Aparicio1, Paola Vidal Montal7 and Diego Benavent8, 1Hospital Germans Trias i Pujol, Barcelona, Spain, 2Hospital Universitari Vall Hebron, Barcelona, Spain, 3Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Spain, 4Hospital Universitari Germans Trias i Pujol, Badalona, Spain, 5Doctor Josep Trueta University Hospital, Girona, Catalonia, Spain, 6Sant Pau Hospital, Barcelona, Catalonia, Spain, 7Bellvitge University Hospital, Barcelona, Spain, 8Hospital Universitari de Bellvitge, Madrid, Spain

    Background/Purpose: Low back pain (LBP) is a multifactorial condition managed by various specialists. AI chatbots like ChatGPT may help clinicians identify probable diagnoses. Given that…
  • Abstract Number: 0308 • ACR Convergence 2025

    Artificial Intelligence Assisted Extraction of Patient-Reported Pain Outcomes in Osteoarthritis Using Prompt Engineering of Large Language Models

    Jainesh Doshi1, Stephen Batter1, Yiyuan Wu2, Alice Santilli1, Sandhya Kannayiram3, Susan Goodman4 and Bella Mehta5, 1Hospital for Special Surgery, New York, 2Weill Cornell Medicine, New York, NY, 3Hospital for Special Surgery, Weill Cornell Medicine, New York, 4Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, 5Hospital for Special Surgery, Weill Cornell Medicine, Jersey City, NJ

    Background/Purpose: Unstructured data in physician notes can be incredibly valuable, especially for understanding patient-reported outcomes (PROs), which are often mentioned in these notes.In this study,…
  • Abstract Number: 2342 • ACR Convergence 2025

    Real-World Effectiveness and Satisfaction in Biologic-Naïve Patients With Psoriatic Arthritis and Limited Joint Involvement Treated With Risankizumab in the United States and Europe

    Andrew Ostor1, Jessica A. Walsh2, Christopher Saffore3, Xiaolan Ye4, Manish Patel5, Ana Biljan6, Jamie Vora7, Isabel Truman8, Molly Edwards8, Gary Milligan8 and William Tillett9, 1Australian National University, Canberra, Australia, 2Division of Rheumatology, Salt Lake City Veterans Affairs Health and University of Utah Health, Salt Lake City, UT, 3AbbVie Inc., waukegan, IL, 4AbbVie Inc., Mettawa, IL, 5AbbVie Inc., North Chicago, IL, 6AbbVie Inc., Buffalo Grove, IL, 7AbbVie Inc., Palatine, IL, 8Adelphi Real World, Bollington, United Kingdom, 9Department of Life Sciences, Centre for Therapeutic Innovation, University of Bath, Bath, United Kingdom

    Background/Purpose: This study evaluated real-world effectiveness and patient- and physician-satisfaction with risankizumab (RZB) for biologic-naïve PsA patients with limited joint involvement or oligoarthritis.Methods: Data were…
  • Abstract Number: 2065 • ACR Convergence 2025

    Pain in Idiopathic Inflammatory Myopathies: A Global Study of Patient Experience

    Lekshmi Minikumari Rahulan1, Shounak Ghosh2, Manali Sarkar3, Didem Saygin4, Karin Lodin5, Rima Shrestha6, Tulika Chatterjee7, Jessica Day8, Samuel Shinjo9, Sreoshy Saha10, Lorenzo Cavagna11, Masataka Kuwana12, Vikas Agarwal13 and Latika Gupta14, 1Sanjay Gandhi Postgraduate Institute of Medical sciences Lucknow, Lucknow, Uttar Pradesh, India, 2Department of Rheumatology, The Royal Wolverhampton NHS Trust, Wolverhampton, UK, Wolverhampton, United Kingdom, 3Sir H. N. Reliance Foundation Hospital and Research Centre, Mumbai, Maharashtra, India., Mumbai, Maharashtra, India, 4Rush University Medical Center, Chicago, IL, 5Department of Gastro, Dermatology and Rheumatology, Karolinska University Hospital, Stockholm, Sweden, Division of Rheumatology, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden, Stockholm, Sweden, 6Department of Internal Medicine, University of Illinois College of Medicine Peoria, Illinois, United States, Department of Research Services, University of Illinois College of Medicine Peoria, Illinois, United States, Illinois, 7Department of Internal Medicine, University of Illinois College of Medicine Peoria, Illinois, United States, Illinois, 8Walter and Eliza Hall Institute, Melbourne, Victoria, Australia, 9Division of Rheumatology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil, Sao Paulo, Brazil, 10Mymensingh Medical College, Mymensingh, Bangladesh, Mymensingh, Bangladesh, 11Associate Professor in Rheumatology (Internal Medicine and Thepaeutics),University of Pavia, Pavia, Lombardy, Italy, Physician in Chief of Myositis Outpatients Clinic,Fondazione IRCCS Policlinico San Matteo, Pavia, Lombardia,Italy, Lombardia, Italy, 12Nippon Medical School Graduate School of Medicine, Tokyo, Japan, 13Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India, 14School of Infection, Inflammation and Immunology, College of Medicine and Health, University of Birmingham; Royal Wolverhampton NHS Trust; Centre for Musculoskeletal Research, School of Biological Sciences, The University of Manchester, Manchester; Francis Crick Institute, London, Birmingham, UK, United Kingdom

    Background/Purpose: Pain remains a significant yet understudied aspect of idiopathic inflammatory myopathies (IIMs), considerably reducing quality of life despite advancements in immunomodulatory therapies. Information obtained…
  • Abstract Number: 1487 • ACR Convergence 2025

    Whole Health Empowerment for Endotypes of Lupus (WHEEL) Program: User Testing Findings on Feasibility, Acceptability, and Opportunities for Intervention Refinement

    Jennifer Rogers1, Amanda Eudy2, Connor Drake3, Tamara Somers4, David Pisetsky5, Christie Clipper6, Ralph Snyderman7, Anna Batsakes6, Leigh Saner6, Dana Burshell3, Mithu Maheswaranathan4, Lisa Criscione-Schreiber4, Rebecca Sadun8, Nathaniel Harris5, Kai Sun8, Kelsey Dunn6, Jenny Herndon6, Vonne Jacobs6 and Megan Clowse9, 1Duke, Durham, NC, 2Duke University, Raleigh, NC, 3Duke University School of Medicine, Durham, 4Duke University School of Medicine, Durham, NC, 5Duke University Medical Center, Durham, NC, 6Duke University, Durham, 7Duke Center for Personalized Health Care, Durham, NC, 8Duke University, Durham, NC, 9Duke University, Chapel Hill, NC

    Background/Purpose: To improve quality of life (QoL) in individuals with SLE, we developed the Whole Health Empowerment for Endotypes of Lupus (WHEEL) program—a 4-month, biweekly,…
  • Abstract Number: 1239 • ACR Convergence 2025

    JAK inhibition appears to alter clinical and neurobiological markers of nociplastic pain in rheumatoid arthritis: a 7T MRI Brain study

    Kristian Stefanov1, Andrew McGucken1, Maxine Arnott1, Tyrone Lau1, Norah Aldehmi1, Vinod Kumar2, Neil McKay3, James Dale4, Lindsay Robertson5, James Brock1, Flavia Sunzini6 and Neil Basu7, 1University of Glasgow, Glasgow, United Kingdom, 2NHS Tayside, Dundee, United Kingdom, 3NHS Lothian, Edinburgh, United Kingdom, 4NHS Lanarkshire, Wishaw, United Kingdom, 5NHS Grampian, Aberdeen, United Kingdom, 6Glasgow University, Glasgow, United Kingdom, 7Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, United Kingdom

    Background/Purpose: Pain remains a prevalent and highly impactful issue for people with rheumatoid arthritis (RA). Among modern day targeted therapies, the janus kinase (JAK) inhibitors…
  • Abstract Number: 1196 • ACR Convergence 2025

    Prevalence of and Factors Associated with Chronic Opioid Use among Individuals with Inflammatory Myopathies

    Anuya Natu1, Haley Zimmerman2, Kristin Wipfler3, Kaleb Michaud4, Yvonne Lee5 and Didem Saygin2, 1John H. Stroger, Jr. Hospital of Cook County, Chicago, IL, 2Rush University Medical Center, Chicago, IL, 3FORWARD, The National Databank for Rheumatic Diseases, Omaha, NE, 4University of Nebraska Medical Center, Omaha, NE, 5Northwestern University, Chicago, IL

    Background/Purpose: Idiopathic inflammatory myopathies (IIM) can be associated with significant pain and functional impairment. While the use of opioids has been documented in other inflammatory…
  • Abstract Number: 0503 • ACR Convergence 2025

    Impact of Olokizumab on Pain in Rheumatoid Arthritis: a Meta-analysis

    Andrey E. Karateev1, Sofia Kuzkina2, Alina Egorova3 and Elena Y. Polishchuk1, 1V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia, 2R-Pharm, Moscow, Russia, 3R-Pharm JSC, Moscow, Russia

    Background/Purpose: Pain is one of the most debilitating symptoms of rheumatoid arthritis (RA) and a major contributor to reduced quality of life. Persistent joint pain…
  • Abstract Number: 0292 • ACR Convergence 2025

    Patterns and Predictors of Longitudinal Trajectories of Pain in Individuals with Inflammatory Myopathies

    Haley Zimmerman1, Ethan Ritz2, Kristin Wipfler3, Kaleb Michaud4 and Didem Saygin1, 1Rush University Medical Center, Chicago, IL, 2Rush Research Informatics Core, Rush University Medical Center, Chicago, IL, 3FORWARD, The National Databank for Rheumatic Diseases, Omaha, NE, 4University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Idiopathic inflammatory myopathies (IIM) have historically been considered a disease of painless weakness. However, recent studies indicate that most patients with IIM experience pain…
  • Abstract Number: 2327 • ACR Convergence 2025

    Persistent Pain in PsA: A Distinct Phenotype of Depression, Fatigue, And Catastrophizing

    Rebecca Haberman1, Kyra Chen2, Adamary Felipe3, Stephanie Eichman3, Uma Scher4 and Jose Scher5, 1NYU Langone Health, New York, NY, 2NYU Grossman School of Medicine and NYU Langone Health Psoriatic Arthritis Center, New York, 3NYU Grossman School of Medicine, New York, 4NYU School of Medicine, Scarsdale, NY, 5New York University School of Medicine, New York, NY

    Background/Purpose: Targeted synthetic and biologic DMARDs have transformed psoriatic arthritis (PsA) treatment. Still, a substantial subset of patients reports persistent joint pain despite well-controlled inflammation.…
  • Abstract Number: 1987 • ACR Convergence 2025

    Evaluating User Engagement and Real-World Impact of a PMR-Specific Digital Symptom Assessment Tool: A 12-Month Analysis of PainSpot™

    Shilpa Venkatachalam1, Erik Stone2, Ian Carroll3, angela Degrassi3, Shelley Fritz4 and David Curtis5, 1Global Healthy Living Foundation, New York, NY, 2Global Healthy Living Foundation, Nyack, NY, 3Global Healthy Living Foundation, Upper Nyack, NY, 4Global Healthy Living Foundation, Kalaheo, HI, 5Global Healthy Living Foundation, Meriden

    Background/Purpose: Polymyalgia rheumatica (PMR) is a systemic inflammatory condition affecting individuals over 50, marked by bilateral shoulder and hip stiffness and pain. Its nonspecific symptoms…
  • Abstract Number: 1461 • ACR Convergence 2025

    Digital Behavioral Therapy Improves Outcome in Patients With Axial Spondyloarthritis And Persistent Pain: Results From a Randomized Controlled Trial

    David Kiefer1, Yade Sonkaya2, Dietmar Krause3, Markus Voglau4, Bernhard Mintrop5, Imke Redeker6, Xenofon Baraliakos7 and Uta Kiltz7, 1Ruhr-Universität Bochum; Private practice of rheumatology, Hattingen, Germany, Herne, Germany, 2Ruhr-Universität Bochum, Herne, Germany, 3Elisabeth-Gruppe, Herne, Germany, Essen, Germany, 4myself, Oldenburg, Germany, 5Private rheumatology practice, Hattingen, Germany, 6Ruhr University Bochum, Bochum, Germany, 7Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany

    Background/Purpose: Axial spondyloarthritis (axSpA) is often associated with persistent pain despite effective anti-inflammatory treatment, substantially impacting patients' quality of life. Digital health applications (DiGAs) provide…
  • Abstract Number: 1238 • ACR Convergence 2025

    Pain Is Associated with An Increased Risk of Frailty in Veterans with Rheumatoid Arthritis

    Nadine El-ayache1, Sayuli Bhide2, Hannah Brubeck3, Punyasha Roul4, Bryant England5, Joshua Baker6, Grant Cannon7, Namrata Singh8, Gary Kunkel9, Ted Mikuls5, Patti Katz10, Dolores Shoback11, Jose Garcia12, Pradeep Suri13, Marianna Gasperi13, Ariela Orkaby14, Una Makris15 and Katherine Wysham16, 1VA Puget Sound Health Care System & University of Washington, Seattle, WA, 2University of Washington, Seattle, WA, 3VA Puget Sound Health Care System, Seattle, WA, 4UNMC, Omaha, NE, 5University of Nebraska Medical Center, Omaha, NE, 6University of Pennsylvania, Philadelphia, PA, 7University of Utah and Salt Lake City VA, Salt Lake City, UT, 8University of Washington, Bellevue, WA, 9University of Utah and George E Wahlen VAMC, Salt Lake City, UT, 10UCSF, San Rafael, CA, 11San Francisco VA Medical Center & University of California San Francisco, San Francisco, CA, 12VA Puget Sound Health Care System, VA GRECC, and University of Washington, Seattle, WA, 13VA PUGET SOUND/UNIVERSITY OF WASHINGTON, Seattle, 14VA Boston Healthcare System & Division of Aging, Brigham and Women’s Hospital, Harvard Medical School & VA Geriatrics Research Education and Clinical Center, Boston, MA, 15UT Southwestern Medical Center and Dallas VA, Dallas, TX, 16VA PUGET SOUND/UNIVERSITY OF WASHINGTON, Seattle, WA

    Background/Purpose: Frailty, an increased vulnerability to stressors, is commonly associated with aging and functional decline. Pain, prevalent among older adults, contributes to frailty in the…
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