Abstracts tagged "pain"

Abstract Number: 1582 • 2012 ACR/ARHP Annual Meeting
Long Term Costs and Cost-Effectiveness of an Integrated Rehabilitation Programme for Chronic Knee Pain
Mike Hurley¹ and Dr Nicola E. Walsh², ¹School of Rehabilitation Sciences, St George's University of London, London, United Kingdom, ²Allied Health Professions, University of the West of England Bristol, Bristol, United Kingdom
Background/Purpose: Management of chronic knee pain incurs enormous direct and indirect healthcare costs. Enabling Self-management and Coping with Arthritic knee Pain through Exercise (ESCAPE-knee pain)…
Abstract Number: 1571 • 2012 ACR/ARHP Annual Meeting
Pain and Fatigue in Adult Patients with Rheumatoid Arthritis – Associations with Demographic Factors, Disease Related Factors, Body Awareness, Emotional and Psychosocial Factors
Helena Lööf¹, Fredrik Saboonchi², Elisabet Welin Henriksson³, Staffan Lindblad⁴ and Unn-Britt Johansson⁵, ¹Sophiahemmet University College, Karolinska Institutet, Department of Clinical Sciences, Danderyd Hospital, Stockholm, Sweden, ²Karolinska Institutet, Department of Clinical Sciences, Danderyd Hospital, Division of Medicine, Stockholm, Sweden, ³Karolinska Institutet, Department of Neurobiology, Care Sciences and Society., Stockholm, Sweden, ⁴Department of Learning, Informatics, Management and Ethics, Karolinska Institutet, Stockholm, Sweden, ⁵Karolinska Institutet, Department of Clinical Sciences, Danderyd Hospital, Stockholm, Sweden

Background/Purpose: Patient´s with Rheumatoid arthritis highlight fatigue as a major concern, as well as pain as a priority for improvement. Previous study has found that…
Abstract Number: 1576 • 2012 ACR/ARHP Annual Meeting
Identifying Subgroups of Rheumatoid Arthritis Patients Based On Levels of Pain, Disability, and Depression
Taylor Draper¹, Sarah R. Ormseth², M. Custodio³, Michael H. Weisman⁴, M.R. Irwin⁵ and Perry M. Nicassio⁵, ¹Psychology, Loma Linda University, Loma Linda, CA, ²Cousins Center for PNI, University of California, Los Angeles, Los Angeles, CA, ³UCLA, Los Angeles, CA, ⁴Cedars-Sinai Medical Center, Los Angeles, CA, ⁵Cousins Center for PNI, UCLA, Los Angeles, CA
Background/Purpose: Pain, disability, and depression are present in various degrees in patients with Rheumatoid Arthritis (RA). In spite of meeting the same diagnostic criteria, some…
Abstract Number: 1487 • 2012 ACR/ARHP Annual Meeting
Incidence of Fibromyalgia Syndrome in Systemic Sclerosis and Rheumatoid Arthritis. Comparative Results According to Clinical Diagnosis, Screening Test with Fibromyalgia Rapid Screening Tool, Diagnosis with ACR1990 and ACR 2010 Criteria
Serge Perrot¹, Mariana Peixoto², Philippe Dieude³, Eric Hachulla⁴, Sébastien Ottaviani⁵ and Yannick Allanore⁶, ¹Internal Medicine and Pain Clinic, Hopital Hotel Dieu, Paris, France, ²Rheumatology Department, Cochin Hospital, Paris, France, ³Rheumatology, Rheumatology departement & INSERM U699, Paris Diderot university, APHP, Bichat hospital, Paris, France, ⁴Department of Internal Medicine, Claude Huriez University Hospital, Lille, France, ⁵Service de Rhumatologie, Hôpital Bichat, APHP, APHP, Paris, France, ⁶Rheumatology, Paris Descartes University, Rheumatology A department, Cochin Hospital, Paris, France
Background/Purpose: Fibromyalgia (FMS) is a chronic widespread pain condition that may be associated with inflammatory chronic disorders like rheumatoid arthritis (RA) and systemic sclerosis (SSc).…
Abstract Number: 1274 • 2012 ACR/ARHP Annual Meeting
Relationship Between Morning Stiffness Duration and Severity, Pain Intensity, and Measures of Disease Activity in a 12 Week Efficacy Study of a Modified (Delayed-Release) Prednisone Plus Disease-Modifying Antirheumatic Drugs in Rheumatoid Arthritis
Frank Buttgereit¹, John R. Kirwan², Kenneth G. Saag³, Reike Alten⁴, Amy Grahn⁵, Patricia Rice⁶ and Maarten Boers⁷, ¹Charité - Universitätsmedizin Berlin, Berlin, Germany, ²Academic Rheumatology Unit, Bristol Royal Infirmary, Bristol, United Kingdom, ³Div Clinical Immun & Rheum, Univ of Alabama-Birmingham, Birmingham, AL, ⁴Charité Univ Medicine, Berlin, Germany, ⁵Clinical Development, Horizon Pharma, Inc, Deerfield, IL, ⁶Statistics, CliniRx Research, Naperville, IL, ⁷Epidemiology & Biostatistics, VU University Medical Center, Amsterdam, Netherlands
Background/Purpose: RA patients typically present with pain and morning stiffness (MS). MS is predictive of both functional disability and escalated RA care, but the best…
Abstract Number: 1230 • 2012 ACR/ARHP Annual Meeting
The Role of Sleep Problems in Conditioned Pain Modulation in Rheumatoid Arthritis
Yvonne C. Lee¹, Bing Lu², Robert R. Edwards³, Ajay Wasan⁴, Nicholas Nassikas⁵, Daniel J. Clauw⁶, Daniel H. Solomon⁷ and Elizabeth W. Karlson⁸, ¹Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ²Rheumatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ³Anesthesiology, Brigham & Womens Hospital, Chestnut Hill, MA, ⁴Anesthesiology, Brigham and Women's Hospital, Chestnut Hill, MA, ⁵Rheumatology, Brigham and Women's Hospital, Boston, MA, ⁶Anesthesiology/Internal Medicine (Rheum), University of Michigan, Ann Arbor, MI, ⁷Division of Rheumatology, Brigham and Women's Hospital, Boston, MA, ⁸Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Among rheumatoid arthritis (RA) patients, pain may exist out of proportion to peripheral inflammation. This observation suggests that central nervous system pain amplification…
Abstract Number: 954 • 2012 ACR/ARHP Annual Meeting
Diagnosis of Secondary Fibromyalgia in an Established Rheumatoid Arthritis Cohort
Yvonne C. Lee¹, Christine K. Iannaccone¹, Michelle A. Frits¹, M. Weinblatt² and Nancy A. Shadick³, ¹Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ²Rheumatology & Immunology, Brigham & Women's Hospital, Boston, MA, ³Rheumatology/Immunology, Brigham and Women's Hospital, Boston, MA
Background/Purpose: The prevalence of fibromyalgia (FM) is 7-10 times higher among rheumatoid arthritis (RA) patients than the general population. However, the diagnosis of FM in…
Abstract Number: 960 • 2012 ACR/ARHP Annual Meeting
Cyclobenzaprine (CBP) and Its Major Metabolite Norcyclobenzaprine (nCBP) Are Potent Antagonists of Human Serotonin Receptor 2a (5HT2a), Histamine Receptor H-1 and á-Adrenergic Receptors: Mechanistic and Safety Implications for Treating Fibromyalgia Syndrome by Improving Sleep Quality
Bruce Daugherty, Leland Gershell and Seth Lederman, Research and Development, Tonix Pharmaceuticals, Inc., New York, NY
Background/Purpose: Bedtime cyclobenzaprine (CBP) improves fibromyalgia symptoms (pain, fatigue, tenderness, and mood) and improves sleep quality (decreases Cyclic Alternating Pattern Type A2 + A3) (1).…
Abstract Number: 744 • 2012 ACR/ARHP Annual Meeting
Racial Differences in Reported Knee Pain Severity Persist Even After Adjustment for Knee Examination and Radiographic Findings: Data From the Osteoarthritis Initiative
Paige Luneburg¹, Laura Yerges-Armstrong², Braxton D. Mitchell² and Marc C. Hochberg¹, ¹Department of Medicine, University of Maryland, Baltimore, MD, ²Departments of Medicine and Epidemiology & Public Health, University of Maryland School of Medicine, Baltimore, MD
Background/Purpose: African Americans have a higher prevalence of both radiographic and symptomatic radiographic knee osteoarthritis (OA) than Caucasians. In addition, African Americans with knee OA…
Abstract Number: 558 • 2012 ACR/ARHP Annual Meeting
Rapid Improvements in Patient Reported Outcomes with Certolizumab Pegol in Patients with Axial Spondyloarthritis, Including Ankylosing Spondylitis and Non-Radiographic Axial Spondyloarthritis: 24 Week Results of a Phase 3 Double Blind Randomized Placebo-Controlled Study
Joachim Sieper¹, Alan J. Kivitz², A.M. Van Tubergen³, Atul A. Deodhar⁴, Geoffroy Coteur⁵, Franz Woltering⁶ and Robert B. M. Landewé⁷, ¹Medical Department I, Rheumatology, Charité University Medicine, Berlin, Germany, ²Altoona Center for Clinical Research, Duncansville, PA, ³Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands, ⁴Oregon Health & Science University, Portland, OR, ⁵UCB Pharma, Brussels, Belgium, ⁶UCB Pharma, Monheim, Germany, ⁷Department of Rheumatology, Amsterdam Rheumatology Center, Amsterdam, Netherlands
Background/Purpose: Axial spondyloarthritis (axSpA) is a form of spondyloarthritis (SpA) that includes both ankylosing spondylitis (AS) and non-radiographic axial SpA (nr-axSpA), as defined by the…
Abstract Number: 339 • 2012 ACR/ARHP Annual Meeting
Differences Between Juvenile and Adult Rodents with Collagen Induced Arthritis
Tracy D. Wilson-Gerwing¹, Isaac V. Pratt², David M.L. Cooper², Tawni I. Silver³ and Alan M. Rosenberg⁴, ¹Pediatrics, University of Saskatchewan, Saskatoon, SK, Canada, ²Anatomy and Cell Biology, University of Saskatchewan, Saskatoon, SK, Canada, ³Small Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK, Canada, ⁴Department of Pediatrics, University of Saskatchewan, Saskatoon, SK, Canada
Background/Purpose: Juvenile idiopathic arthritis (JIA) is among the most common chronic diseases of childhood. Arthritis is a potentially disabling disease that can result in ongoing…
Abstract Number: 343 • 2012 ACR/ARHP Annual Meeting
Functional Impairment in an Animal Model for Rheumatoid Arthritis Assessed As Changes in Gait Is Due to Joint Destruction but Not Synovial Inflammation Per Se
Gregor Bauer¹, Constantin Aschauer¹, Birgit Niederreiter², Josef S. Smolen³, Kurt Redlich² and Silvia Hayer², ¹Dep. of Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, ²Department of Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, ³Division of Rheumatology, Department of Internal Medicine III,, Medical University of Vienna and Hietzing Hospital, Vienna, Austria
Background/Purpose: To investigate the individual impact of synovial inflammation, subchondral bone erosion or cartilage damage on functional impairment in an animal model of Rheumatoid Arthritis…
Abstract Number: 2448 • 2012 ACR/ARHP Annual Meeting
Sustained Improvement Physical Function Following an Integrated Rehabilitation Programme for Chronic Knee Pain
Mike Hurley¹ and Dr Nicola E. Walsh², ¹School of Rehabilitation Sciences, St George's University of London, London, United Kingdom, ²Allied Health Professions, University of the West of England Bristol, Bristol, United Kingdom
Background/Purpose: Chronic knee pain causes personal suffering and impairs physical function and quality of life. Usual primary care involves prolonged drug therapy in spite of…
Abstract Number: 95 • 2012 ACR/ARHP Annual Meeting
Smoking Is Associated with Worse and More Widespread Pain, Worse Disease Activity, Function, Fatigue and Health Related Quality of Life in Patients with Axial Spondyloarthritis –Results From a Population Based Cohort
Ann B. I. Bremander¹, Ingemar F. Petersson², Emma Haglund³, Stefan Bergman⁴ and Lennart TH Jacobsson⁵, ¹Department of Exercise Physiology, Biomechanics and Health, Halmstad University School of Business and Engineering, Halmstad, Sweden, ²Lund University, Lund, Sweden, ³Research and Development Centre, Spenshult Hospital for Rheumatic Diseases, Halmstad, Sweden, ⁴Spenshult Research and Development Center, Halmstad, Sweden, ⁵Department of Rheumatology and Inflammation Research, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
Background/Purpose: In subjects with early axial Spondyloarthritis (SpA) smoking has recently been associated with earlier onset of disease, worse lesions of the sacroiliac joints and…
Abstract Number: 2436 • 2012 ACR/ARHP Annual Meeting
Clinical Effectiveness and Costs of an Integrated Rehabilitation Programme Compared with Outpatient Physiotherapy for Chronic Knee Pain
Mike Hurley¹, Dr Nicola E. Walsh² and Sally Jessep³, ¹School of Rehabilitation Sciences, St George's University of London, London, United Kingdom, ²Allied Health Professions, University of the West of England Bristol, Bristol, United Kingdom, ³Physiotherapy Out-Patients Department, Kent, United Kingdom
Background/Purpose: Chronic knee pain is a major cause of disability. Management guidelines recommend exercise and self-management interventions. We previously described a rehabilitation programme that integrates…

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