Abstracts tagged "pain and therapy"

Abstract Number: 2229 • 2017 ACR/ARHP Annual Meeting
The Effect of Intra-Articular Neurotoxin on Arthritis Pain and Substance P Expression in the Dorsal Root Ganglion: Results from Murine Arthritis Models
Hollis Krug^1,2, Sandra Frizelle³, Nicole Blanshan⁴, Christopher W. Dorman³ and Maren Mahowald^2,5, ¹Medicine, Minneapolis VAHCS, Minneapolis, MN, ²Medicine, University of Minnesota Medical School, Minneapolis, MN, ³Research, Minneapolis VA Health Care System, Minneapolis, MN, ⁴Research, Minneapolis VAHCS, Minneapolis, MN, ⁵Rheumatology/ Dept of Medicine, Minneapolis VA and Univ MN Med School, SAINT PAUL, MN
Background/Purpose : Substance P (SP) release and binding to NK-1 produces pain transmission. Neurotoxins (NT) that prevent release of SP, such as onabotulinum toxin (BoNT/A),…

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Abstracts tagged "pain and therapy"

The Effect of Intra-Articular Neurotoxin on Arthritis Pain and Substance P Expression in the Dorsal Root Ganglion: Results from Murine Arthritis Models