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Abstracts tagged "pain and synovitis"

  • Abstract Number: 2181 • ACR/ARHP Annual Meeting 2017

    Is a Decrease in MRI-Defined Inflammation Associated with a Decrease in Pain in Patients with Hand Osteoarthritis? a Two-Year Follow-up Study

    S. van Beest1, W. Damman1, R. Liu1 and M. Kloppenburg2, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Rheumatology and Clinical Epidemiology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: Joint pain in hand osteoarthritis (OA) is associated with synovitis in cross-sectional studies. Therefore we hypothesized that synovitis could be a target for treatment.…
  • Abstract Number: 2208 • ACR/ARHP Annual Meeting 2017

    A Novel Omeract MRI Scoring System Providing Insights in the Association of MRI Synovitis and Bone Marrow Lesions with Pain in Thumb Base Osteoarthritis

    F.P.B. Kroon1, S. van Beest1, W. Damman1, R. Liu1, J.L. Bloem2, M. Reijnierse2 and M. Kloppenburg1,3, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Radiology, Leiden University Medical Center, Leiden, Netherlands, 3Clinical Epidemiology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: Osteoarthritis (OA) in the thumb base joints (first carpometacarpal [CMC1] and scaphotrapeziotrapezoid [STT]) is highly prevalent and disabling, however much is still unknown about…
  • Abstract Number: 2227 • ACR/ARHP Annual Meeting 2017

    S100A9 Induces a Pain Response during Experimentally Induced Acute Synovitis

    Arjen B. Blom1, Edwin J. W. Geven1, Martijn H. van den Bosch1, Esmeralda N. Blaney Davidson1, Peter M. van der Kraan1 and Peter L. van Lent2, 1Experimental Rheumatology, Radboud university medical center, Nijmegen, Netherlands, 2Radboud University Nijmegen Medical Center, Rheumatology, Nijmegen, Netherlands

    Background/Purpose: Synovitis-associated pain is an important aspect of arthritis pathology. Several inflammatory mediators released by the synovium have been implicated in the regulation of pain,…
  • Abstract Number: 1250 • ACR/ARHP Annual Meeting 2013

    Serological Markers Of Structural Integrity and Inflammation Is Associated With Pain In Osteoarthritis

    Anne Sofie Siebuhr1, Lars Arendt-Nielsen2, Thomas Navndrup Eskehave3, Morten Asser Karsdal4, Kristian Kjaer Petersen5, Ole Simonsen6 and Anne C. Bay-Jensen7, 1Cartilage Biomarkers and Research, Nordic Bioscience, Herlev, Denmark, 2Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Center for Sensory-Motor Interaction, Aalborg, Denmark, 3Center for Clinical and Basic Research and C4Pain, Aalborg, Denmark, 4Nordic Bioscience, Biomarkers and Research, Herlev, Denmark, 5Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Denmark, Center for Sensory-Motor Interaction, Aalborg, Denmark, 6Frederikshavn Hospital, Frederikshavn, Denmark, 7Rheumatology, Nordic Bioscience, Biomarkers and Research, Herlev, Denmark

    Background/Purpose: Pain is associated with diagnosed osteoarthritis (OA), but little clinically association is found between joint integrity and the pain the individual patient experience. Peripheral…

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