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Abstracts tagged "pain and synovial cells"

  • Abstract Number: 150 • ACR/ARHP Annual Meeting 2013

    A Subset Of Osteoarthritis Individuals Has Elevated IL-6 Pathway Activation Associated With Worse Symptoms

    Michael Kuziora1, Zheng Liu2, Brandon W. Higgs2, Philip Brohawn2, Kim Lehmann2, Fernanda Pilataxi2, Katie Streicher2, Lydia Greenlees1, Meina Liang3, Rozanne Lee4, Amy Schneider4, Raffaella Faggioni4, Yihong Yao2 and Koustubh Ranade2, 1Translational Science, MedImmune, LLC, Gaithersburg, MD, 2Translational Sciences, MedImmune, LLC, Gaithersburg, MD, 3Dmpk, MedImmune, LLC, Hayward, CA, 4DMPK, MedImmune, LLC, Hayward, CA

    Background/Purpose:  Elevated levels of the pro-inflammatory cytokine IL-6 have been found in the affected joint of patients with osteoarthritis (OA), although the prevalence of OA…

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