Abstracts tagged "pain and monoclonal antibodies"

Abstract Number: 535 • 2019 ACR/ARP Annual Meeting
Exploratory Analysis of a Phase 2b Study Confirms Substantial Pain Improvement with Anti-GM-CSF Monoclonal Antibody Otilimab (GSK3196165) in Patients (Pts) with Active RA
Christopher D. Buckley¹, Jesus A. Simon Campos ², Vyacheslav Zhdan ³, Brandon Becker ⁴, Olivier Collignon ⁵, Carol Hawkes ⁶, Mark Layton ⁷, Jatin Patel ⁸, Katherine Davy ⁷, Anubha Gupta ⁷ and Sofia Fernandes ⁵, ¹Rheumatology Research Group, University of Birmingham, Birmingham, United Kingdom, ²Köhler & Milstein Research, Mérida, Mexico, ³M.V. Sklifosovskyi Poltava Regional Clinical Hospital, Poltava, Ukraine, ⁴GSK, Upper Providence, PA, ⁵GSK, Stevenage, United Kingdom, ⁶GSK, Stockley Park, United Kingdom, ⁷GlaxoSmithKline, Stevenage, United Kingdom, ⁸GlaxoSmithKline, Stockley Park, United Kingdom
Background/Purpose: Treatment of pain remains a priority for patients (pts) with RA. Otilimab (GSK3196165) is a human mAb that inhibits GM-CSF, a key driver in…

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