Abstracts tagged "Paget’s disease"

Abstract Number: 1949 • 2019 ACR/ARP Annual Meeting
The p.R321C Mutation in P62 Associated with Paget’s Disease of Bone Leads to a Change of Localization of the Protein in Human Osteoclasts
Nerea Gestoso-Uzal ¹, Ricardo Usategui-Martín ¹, Rogelio González-Sarmiento ¹ and Javier Del Pino-Montes¹, ¹Salamanca Institute of Biomedical Research (IBSAL), University Hospital of Salamanca- University of Salamanca, Salamanca-CSIC, Spain, Salamanca, Castilla y Leon, Spain
Background/Purpose: Paget´s disease of bone (PDB) is a chronic bone metabolic disorder. Currently, PDB is a focal disorder characterized by an increase in bone turnover…
Abstract Number: 2317 • 2018 ACR/ARHP Annual Meeting
Characterization of Paget´s Disease of Bone Patients from the South of Portugal (Algarve and Alentejo) – Clinical and Genetic Aspects
Graça Sequeira¹, Pedro Carvalho², Célia Ribeiro¹, Ana Alfaia³, Natércia Conceição⁴ and Leonor Cancela⁴, ¹Rheumatology, University Hospital Center of Algarve, Faro, Portugal, Faro, Portugal, ²Serviço de Reumatologia, Hospitais Universitários de Coimbra, Coimbra, Portugal, Coimbra, Portugal, ³Centre of Marine Sciences, University of Algarve, Faro, Portugal, Faro, Portugal, ⁴Department of Biomedical Sciences and Medicine, University of Algarve, Faro, Portugal, Faro, Portugal
Background/Purpose: Paget’s disease of bone (PDB) is a metabolic bone disorder whose prevalence increases with age and affects ~3% of Caucasian individuals older than 55…

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