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Abstracts tagged "oxidative stress"

  • Abstract Number: 2746 • ACR/ARP Annual Meeting 2019

    Dimethyl Fumarate Ameliorates the GATA6 Deficiency-Induced Pulmonary Hypertension by Normalizing Oxidative and ER Stress

    Asako Ichihara1, Tetsuo Toyama 2, Tatiana Kudryashova 3, Yuanjun Shen 3, Dmitry Goncharov 3, Elena Goncharova 3 and Maria Trojanowska 2, 1Arthritis Center, Boston University School of Medicine, Brookline, MA, 2Arthritis Center, Boston University School of Medicine, Boston, 3Pulmonary, Allergy & Critical Care Division, University of Pittsburgh Department of Medicine, Pittsburgh

    Background/Purpose: Pulmonary arterial hypertension (PAH) is a leading cause of death in patients with limited form of systemic sclerosis (SSc). We have previously reported that…

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