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Abstracts tagged "outcome measures and vasculitis"

  • Abstract Number: 2967 • 2016 ACR/ARHP Annual Meeting

    Identifying Core Domains for BehçEt’s Syndrome Trials: An International Physician and Patient Delphi Exercise

    Alexa Meara1, Yesim Ozguler2, Alfred Mahr3, Haner Direskeneli4, Ahmet Gul5, Yusuf Yazici6, Hasan Yazici2, Peter A. Merkel7 and Gulen Hatemi2, 1Internal Medicine/Rheumatology, The Ohio State University, Columbus, OH, 2Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, 3Hospital Saint-Louis, Paris, France, 4Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey, 5Department of Internal Medicine, Division of Rheumatology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, 6Rheumatology, New York University Medical Center, La Jolla, CA, 7Division of Rheumatology, University of Pennsylvania, Philadelphia, PA

    Background/Purpose: An unmet need for reliable, validated, and widely accepted outcome measures for trials in BehetÕs syndrome (BS) was identified through: i) a systematic review;…
  • Abstract Number: 871 • 2015 ACR/ARHP Annual Meeting

    Clinicians’ Perspective on Aspects of ANCA-Associated Vasculitis That Influence Patients’ Function and General Health: A Delphi Exercise Based on the International Classification of Function, Disability and Health

    Nataliya Milman1, Peter Tugwell2, Annelies Boonen3 and Peter A. Merkel4, 1Division of Rheumatology, University of Ottawa, Ottawa, ON, Canada, 2Center For Global Health, Institute of Population Hlth, Ottawa, ON, Canada, 3Maastricht University Medical Center, Maastricht, Netherlands, 4Penn Vasculitis Center, Division of Rheumatology, University of Pennsylvania, Philadelphia, PA

    Background/Purpose: ANCA-associated vasculitis (AAV) is a multisystem condition that results in significant level of morbidity and functional limitations for many patients. Previous studies showed that…
  • Abstract Number: 873 • 2015 ACR/ARHP Annual Meeting

    The ANCA-Vasculitis Index of Damage (AVID): Performance of a New Damage Instrument

    Eli Miloslavsky1,2, Na Lu3, Sebastian Unizony3, Hyon K. Choi3, Peter A. Merkel4, Philip Seo5, Robert F. Spiera6, Carol A. Langford7, Gary S. Hoffman7, Cees Kallenberg8, E. William St.Clair9, Nadia Tchao10, Fernando Fervenza11, Paul A. Monach12, Ulrich Specks13 and John H. Stone14, 1Division of Rheumatology, Massachusetts General Hopsital, Boston, MA, 2Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Boston, MA, 3Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 4Penn Vasculitis Center, Division of Rheumatology, University of Pennsylvania, Philadelphia, PA, 5Division of Rheumatology, Johns Hopkins, Baltimore, MD, 6Rheumatology, Hospital for Special Surgery, New York, NY, 7Rheumatology, Cleveland Clinic, Cleveland, OH, 8Rheumatology/Clin Immunol AA21, Univer Med Center Groningen, Groningen, Netherlands, 9Rheumatology and Immunology, Duke University, Durham, NC, 10ITN, San Francisco, CA, 11Mayo Clinic, Rochester, MN, 12Rheumatology, Boston University School of Medicine, Boston, MA, 13Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, MN, 14Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston, MA

    Background/Purpose: Damage related to active disease or its treatment is an important outcome measure in ANCA-associated vasculitis (AAV).  The Vasculitis Damage Index (VDI), the principal…
  • Abstract Number: 746 • 2013 ACR/ARHP Annual Meeting

    Glucocorticoid Treatment and Damage In The Antineutrophil- Cytoplasm Antibody Associated Vasculitides

    Joanna Robson1, Helen Doll2, Ravi Suppiah3, Oliver Flossmann4, Lorraine Harper5, Peter Hoglund6, David Jayne7, Alfred Mahr8, Kerstin Westman9 and Raashid A. Luqmani10, 1Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Oxford, United Kingdom, 2Department of Population Health, University of East Anglia, Norwich, United Kingdom, 3Department of Rheumatology, Auckland District Health Board, Auckland, New Zealand, 4Nephrology, Royal Berkshire Hospital, Reading, United Kingdom, 5Nephrology, University of Birmingham, Birmingham, United Kingdom, 6Competence Centre fo Clinical Research, Skane University Hospital, Lund, Sweden, 7Vasculitis and Lupus Clinic, Addenbrookes Hospital University of Cambridge, Cambridge, United Kingdom, 8Department of Internal Medicine, Hospital Saint-Louis, Paris, France, 9Nephrology and Transplantation, Skåne University Hospital Malmö, Lund University, Malmö, Sweden, 10Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science, University of Oxford, Oxford, United Kingdom

    Background/Purpose: Granulomatosis with polyangiitis [Wegener's] (GPA) and microscopic polyangiitis (MPA) are antineutrophil-cytoplasm antibody associated vasculitides (AAVs). Damage is quantified by the Vasculitis Damage Index (VDI).…
  • Abstract Number: 1524 • 2012 ACR/ARHP Annual Meeting

    The Use of the International Classification of Function, Disability and Health As a Conceptual Framework for Comparison of the Content of Core Outcome Instruments with the Patient Perspective in Vasculitis

    Nataliya Milman1, Peter A. Merkel2, Annelies Boonen3, Lee Strunin4, Ryan Borg4 and Peter Tugwell5, 1Rheumatology, Ottawa Hospital, Riverside Campus, Ottawa, ON, Canada, 2University of Pennsylvania, Philadelphia, PA, 3Department of Internal Medicine, Division of Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, 4Community Health Sciences, Boston University School of Public Health, Boston, MA, 5Institute of Population Health, Center For Global Health, University of Ottawa, Ottawa General Hospital, Ottawa, ON, Canada

    Background/Purpose: The International Classification of Functioning, Disability and Health (ICF) is a general health model endorsed by the World Health Organization. It describes health along…
  • Abstract Number: 1527 • 2012 ACR/ARHP Annual Meeting

    Patient Global Assessments for Disease Activity Are Predictive of Future Flare in Granulomatosis with Polyangiitis (Wegener’s)

    Gunnar Tomasson1, John C. Davis Jr.2, Gary S. Hoffman3, W. Joseph McCune4, Ulrich Specks5, Robert F. Spiera6, E. William St. Clair7, John H. Stone8 and Peter A. Merkel9, 1Department of Public Health Sciences, University of Iceland, Reykjavik, Iceland, 2Genentech, Inc, South San Francisco, CA, 3Rheumatic & Immunologic Dis, Cleveland Clinic, Cleveland, OH, 4Int Med/ Rheum, University of Michigan, Ann Arbor, MI, 5Mayo Clinic, Rochester, MN, 6Rheumatology, Hospital for Special Surgery, New York, NY, 7Medicine, Duke University Medical Center, Durham, NC, 8Rheumatology, Massachusetts General Hospital, Boston, MA, 9University of Pennsylvania, Philadelphia, PA

    Background/Purpose:  In granulomatosis with polyangiitis GPA), disease activity is assessed by physician-based measures. In some other rheumatic diseases, such as rheumatoid arthritis (RA) and ankylosing…
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