Abstracts tagged "outcome measures and spondylarthritis"

Abstract Number: 634 • 2018 ACR/ARHP Annual Meeting
Spinal Mobility Measures Allow Discrimination of Subgroups of Different Activity and Severity in Early Axial Spondyloarthritis
Mary Lucy Marques^1,2, Sofia Ramiro^2,3, Floris van Gaalen², Philippe Goupille⁴, Maxime Dougados⁵ and Désirée van der Heijde⁶, ¹Rheumatology, Centro Hospitalar e Universitário de Coimbra, Portugal & Leiden University Medical Center, Leiden, Netherlands, ²Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ³Zuyderland Medical Center, Heerlen & Leiden University Medical Center, Leiden, Netherlands, ⁴Université François-Rabelais, Tours, France, ⁵Department of Rheumatology, Paris Descartes University and Cochin Hospital, Paris, France, ⁶Leiden University Medical Centre, Leiden, Netherlands
Background/Purpose: Spinal mobility has been mostly investigated in cohorts of patients with established AS. However, it was scarcely studied in the early phases of the…
Abstract Number: 635 • 2018 ACR/ARHP Annual Meeting
Measuring Spinal Mobility over Time in Early Axial Spondyloarthritis: Can We Do It Reliably?
Mary Lucy Marques^1,2, Sofia Ramiro^3,4, Floris van Gaalen², Philippe Goupille⁵, Maxime Dougados⁶ and Désirée van der Heijde⁷, ¹Rheumatology, Centro Hospitalar e Universitário de Coimbra, Portugal & Leiden University Medical Center, Leiden, Netherlands, ²Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ³Department of Rheumatology, Leiden University Medical Centre, Leiden, Netherlands, ⁴Zuyderland Medical Center, Heerlen & Leiden University Medical Center, Leiden, Netherlands, ⁵Université François-Rabelais, Tours, France, ⁶Department of Rheumatology, Paris Descartes University and Cochin Hospital, Paris, France, ⁷Leiden University Medical Centre, Leiden, Netherlands
Background/Purpose: The use of spinal mobility measures (SMMs), at the individual level and in the follow-up of patients with early axSpA has not yet been…
Abstract Number: 2502 • 2017 ACR/ARHP Annual Meeting
Defining Clinically Important Worsening Based on ASDAS-CRP for Axial Spondyloarthritis: A Data-Based Consensus By the Assessment in Spondyloarthritis International Society (ASAS)
Anna Molto¹, Laure Gossec², Robert B.M. Landewé³, Désirée van der Heijde⁴ and Maxime Dougados⁵, ¹Hôpital Cochin, Department of Rheumatology, Paris Descartes University, Paris, France, ²UPMC University Paris 06, Pitié-Salpétrière Hospital, Paris, France, ³Amsterdam Rheumatology & Immunology Center, Netherlands, Amsterdam, Netherlands, ⁴Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁵Department of Rheumatology, Paris Descartes University, Hôpital Cochin, Paris, France
Background/Purpose: Disease flares are increasingly used as outcomes in axial spondyloarthritis (axSpA) trials or observational studies. The objective of this initiative was to define a…
Abstract Number: 2552 • 2017 ACR/ARHP Annual Meeting
Inter-Connections between Fatigue, Pain and Patient Global Assessement in Patients with Active Spondyloarthritis Followed in the Daily Clinic
Ole Rintek Madsen, Center for Rheumatology and Spine Diseases & The DANBIO Registry, Copenhagen University Hospital Rigshospitalet Gentofte and Glostrup, Denmark, Hellerup, Denmark
Background/Purpose: The Assessment of SpondyloArthritis international Society (ASAS) has selected fatigue, pain and patient global assessment (PaGl) as key patient-reported outcome measures in clinical trials…
Abstract Number: 396 • 2016 ACR/ARHP Annual Meeting
Performance of Disease Activity Measures in Juvenile Spondyloarthritis in a Placebo Controlled Trial with Infliximab
Sofia Ramiro¹, Julio Casasola², Désirée van der Heijde³, RBM Landewé⁴ and Rubén Burgos-Vargas⁵, ¹Leiden University Medical Center, Leiden, Netherlands, ²Rheumatology, Hospital General de Mexico, Mexico, Mexico, ³Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁴Department of Rheumatology, Amsterdam Rheumatology Center, Amsterdam, Netherlands, ⁵Rheumatology, Hospital General de Mexico, Mexico city, Mexico
Background/Purpose: Several outcome measures in trials with juvenile-onset spondyloarthritis (Jo-SpA) have been borrowed from trials in juvenile idiopathic arthritis and from adult spondyloarthritis, but a…
Abstract Number: 1282 • 2016 ACR/ARHP Annual Meeting
Feasibility and Reliability of the Spondyloarthritis Research Consortium of Canada Sacroiliac Joint Structural Score for Children with Spondyloarthritis
Nancy A. Chauvin¹, Walter P. Maksymowych^2,3, Robert G. Lambert⁴, Jacob Jaremko⁵, David M. Biko¹, Timothy G. Brandon⁶, Joel Paschke³ and Pamela F. Weiss^7,8, ¹Radiology, Children's Hospital of Philadelphia, Philadelphia, PA, ²Medicine, University of Alberta, Edmonton, AB, Canada, ³CaRE Arthritis, Edmonton, AB, Canada, ⁴Radiology, University of Alberta, Edmonton, AB, Canada, ⁵Radiology, Radiology, University of Alberta, Edmonton, AB, Canada, ⁶Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, ⁷Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, ⁸Division of Rheumatology, Center for Pediatric Clincial Effectiveness, Children's Hospital of Philadelphia, Philadelphia, PA
Background/Purpose: There is a critical need for measures to evaluate structural progression in the pediatric sacroiliac joint. We aimed to evaluate the precision and construct…
Abstract Number: 2331 • 2015 ACR/ARHP Annual Meeting
Agreement Between Patient’s and Physician’s Reported Bath Ankylosing Spondylitis Disease Activity Index in Patients with Axial Spondyloarthritis
Liana Ghukasyan¹, Adrien Etcheto², Anna Moltó³ and Maxime Dougados³, ¹Rheumatology B Department, Paris-Descartes University, Cochin Hospital, Paris, France, ²Rheumatology B, Rheumatology B Department, Paris-Descartes University, Cochin Hospital, Paris, France, ³Paris Descartes University, Rheumatology Department, Cochin Hospital, AP-HP. INSERM (U1153): Clinical Epidemiology and Biostatistics, PRES Sorbonne Paris-Cité, Paris, France
Background/Purpose : The Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) is the more frequently used index for evaluating disease activity in Spondyloarthritis (SpA) in clinical…
Abstract Number: 561 • 2014 ACR/ARHP Annual Meeting
A Psychometric Analysis of Outcome Measures in Trials of Peripheral Spondyloarthritis
Sofia Ramiro¹, Maureen C. Turina², Dominique L. Baeten³, Philip J. Mease⁴, Jacqueline E. Paramarta², In-Ho Song⁵, Aileen L. Pangan⁶ and Robert Landewé⁷, ¹Clinical Immunology and Rheumatology, Amsterdam Rheumatology Center/University of Amsterdam, Amsterdam, Netherlands, ²Department of Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, ³Department of Clinical Immunology and Rheumatology and Department of Experimental Immunology, Academic Medical Centre/University of Amsterdam, Amsterdam, Netherlands, ⁴Division of Rheumatology Research, Swedish Medical Center and University of Washington, Seattle, WA, ⁵AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany, ⁶AbbVie Inc., North Chicago, IL, ⁷Division of Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands
Background/Purpose: We assessed the discriminatory aspects of disease activity measures and response criteria between adalimumab (ADA) and placebo (PBO) in 2 studies of patients (pts)…
Abstract Number: 1541 • 2013 ACR/ARHP Annual Meeting
Spinal Mobility Gets Impaired In a Fixed Order In Patients With Ankylosing Spondylitis: 12-Year OASIS Results
Sofia Ramiro¹, Robert Landewé², Désirée van der Heijde³, Carmen Stolwijk⁴, Maxime Dougados⁵, Filip Van den Bosch⁶ and A.M. van Tubergen⁷, ¹Clinical Immunology & Rheumatology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands, ²Academic Medical Center Amsterdam & Atrium Medical Center, Heerlen, Netherlands, ³Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁴Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, ⁵Rheumatology B Department, Paris-Descartes University, Cochin Hospital, Paris, France, ⁶Ghent University Hospital, Ghent, Belgium, ⁷Department of Internal Medicine, Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands
Background/Purpose: Spinal mobility is impaired in patients with ankylosing spondylitis (AS) compared to normal subjects. However, the extent of impairment and the relative contribution of…
Abstract Number: 1525 • 2013 ACR/ARHP Annual Meeting
Measurement Of Lateral Spinal Flexion and Schober Is Sufficient To Be Informed About Spinal Mobility In Patients With Ankylosing Spondylitis: 12-Year OASIS Results
Sofia Ramiro¹, Robert Landewé², Désirée van der Heijde³, Carmen Stolwijk⁴, Maxime Dougados⁵, Filip Van den Bosch⁶ and A.M. van Tubergen⁷, ¹Clinical Immunology & Rheumatology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands, ²Academic Medical Center Amsterdam & Atrium Medical Center, Heerlen, Netherlands, ³Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁴Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, ⁵Rheumatology B Department, Paris-Descartes University, Cochin Hospital, Paris, France, ⁶Ghent University Hospital, Ghent, Belgium, ⁷Department of Internal Medicine, Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands
Background/Purpose: We have shown that spinal mobility gets impaired in a fixed order in ankylosing spondylitis (AS), with the highest impairment in lumbar spine. We…
Abstract Number: 1510 • 2013 ACR/ARHP Annual Meeting
Disease Activity In Male Smokers Has A >10-Fold Amplified Effect On Radiographic Damage In Comparison With Female NON-Smokers In Ankylosing Spondylitis
Sofia Ramiro^1,2, A.M. van Tubergen³, Robert Landewé⁴, Carmen Stolwijk⁵, Maxime Dougados⁶, Filip Van den Bosch⁷ and Désirée van der Heijde⁸, ¹Clinical Immunology & Rheumatology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands, ²Rheumatology, Hospital Garcia de Orta, Almada, Portugal, ³Department of Internal Medicine, Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, ⁴Academic Medical Center Amsterdam & Atrium Medical Center, Heerlen, Netherlands, ⁵Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, ⁶Rheumatology B Department, Paris-Descartes University, Cochin Hospital, Paris, France, ⁷Ghent University Hospital, Ghent, Belgium, ⁸Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: We have shown that disease activity has an effect on radiographic progression over the long-term and that gender and symptom duration are effect modifiers.…

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