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Abstracts tagged "outcome measures and rheumatoid arthritis (RA)"

  • Abstract Number: 1809 • 2014 ACR/ARHP Annual Meeting

    Is Team Care Better? a Comparison of Rheumatoid Arthritis Disease Activity Among Patients Cared for in Practices with Nurse Practitioners and Physicians Assistants Versus Rheumatologist Only

    DH Solomon1,2, Liana Fraenkel3, Bing Lu1, Erika Brown1, Peter Hsun Tsao4, Elena Losina5, Jeffrey N. Katz6 and Asaf Bitton7, 1Brigham and Women's Hospital, Boston, MA, 2Rheumatology, Brigham and Women's Hospital, Boston, MA, 3Rheumatology, Yale University School of Medicine, Veterans Affairs Connecticut Healthcare Systems, New Haven, CT, 4Rheumatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 5Orthopaedic and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA, 6Rheumatology and Orthopedics, Brigham and Women's Hospital, Boston, MA, 7Medicine, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: The Affordable Care Act proposes more widespread use of mid-level providers (MLPs), such as nurse practitioners and physician assistants, but little is known about…
  • Abstract Number: 2682 • 2013 ACR/ARHP Annual Meeting

    Incidence Trends and Predictors Of Orthopedic Surgery In Patients With Rheumatoid Arthritis – Results From a Well Defined Population

    Korosh Hekmat1, Lennart Jacobsson2, Jan-Åke Nilsson3, Minna Willim4, Martin Englund5, Ingemar F. Petersson6 and Carl Turesson2, 1Department of Clinical Sciences, Section of Rheumatology, Malmö, Lund University, Malmö, Sweden, 2Section of Rheumatology, Department of Clinical Sciences, Malmö, Lund University, Malmö, Sweden, 3Rheumatology, Department of Clinical Sciences, Malmö, Lund University, Malmö, Sweden, 4Department of Clinical Sciences Malmö, Section of Rheumatology, Lund University, Malmö, Sweden, 5Department of Orthopedics, Clinical Sciences Lund,, Lund University, Lund, Sweden, 6Musculoskeletal Scienes, Department of Orthopedics, Clinical Sciences, Lund, Sweden

    Background/Purpose:  Orthopedic surgery is used effectively in many patients with severe rheumatoid arthritis (RA). The aim of modern pharmacologic treatment is to prevent joint destruction…
  • Abstract Number: 2371 • 2013 ACR/ARHP Annual Meeting

    Is a Single Variable, The Swollen Joint Count, Valid As An Outcome Measure Separate From Being In An Index Measure? An Analysis From The Prospective, Biologic Treatment Registry Across Canada

    J. Carter Thorne1, Boulos Haraoui2,3, William G. Bensen4, Algis Jovaisas5, Jude F. Rodrigues6, Denis Choquette2, Alice V. Klinkhoff7, Emmanouil Rampakakis8,9, John S. Sampalis8,9, Francois Nantel10, Allen J. Lehman11, May Shawi12 and Susan M. Otawa11, 1Southlake Regional Health Centre, Newmarket, ON, Canada, 2Rheumatology, Institut de rhumatologie de Montréal (IRM), Montréal, QC, Canada, 3Department of Medicine, Centre Hospitalier de l’Université de Montréal, Montréal, QC, Canada, 4Department of Medicine, Division of Rheumatology, Clinical Professor, McMaster University, Hamilton, ON, Canada, 5Division of Rheumatology, University of Ottawa, Ottawa, ON, Canada, 6Rheumatology, Windsor, ON, Canada, 7The Mary Pack Arthritis Ctr, Vancouver, BC, Canada, 8JSS Medical Research, Montreal, QC, Canada, 9Jewish General Hospital, McGill University, Montreal, QC, Canada, 10Janssen Inc., Toronto, ON, Canada, 11Medical Affairs, Janssen Inc., Toronto, ON, Canada, 12Medical Affairs, Janssen Canada Inc, Toronto, ON, Canada

    Background/Purpose: The importance of joint counts as measures of synovitis is reflected in their prominence in all major clinical composite indices, the Disease Activity Score…
  • Abstract Number: 2279 • 2013 ACR/ARHP Annual Meeting

    Assessment Of Global Disease Activity In Rheumatoid Arthritis By Patients and Physicians: Cultural Differences Among Countries In The Meteor Database

    E. Gvozdenovic1, R. Wolterbeek2, C.F. Allaart1, Claiton Brenol3, Arvind Chopra4, Maxime Dougados5, Paul Emery6, D. van der Heijde7, T.W.J. Huizinga1, Jonathan Kay8, Emilio Martín Mola9, Robert J. Moots10, José A. P. Da Silva11, Josef S. Smolen12, Douglas J. Veale13 and R. Landewe14, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Biostatistics, Leiden University Medical Center, Leiden, Netherlands, 3Universidade Federal do Rio Grande do Sul, Porto Alegre RS, Brazil, 4Rheumatology, Center for Rheumatic Diseases, Pune, India, 5Rheumatology B Department, Paris-Descartes University, Cochin Hospital, Paris, France, 6Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 7Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 8UMass Memorial Medical Center and University of Massachusetts Medical School, Worcester, MA, 9Rheumatology. La Paz Hospital. IdiPaz, Madrid, Spain, 10Clinical Sciences Centre, University of Liverpool, Liverpool, United Kingdom, 11Serviço de Reumatologia, Centro Hospitalar e Universitário de Coimbra – Hospitais da Universidade de Coimbra, E.P.E., Coimbra, Portugal, 12Medical University of Vienna, Vienna, Austria, 13Rheumatology, St. Vincent's University Hospital, Dublin 4, Ireland, 14Division of Clinical Immunology and Rheumatology, Academic Medical Center / University of Amsterdam, Amsterdam, Netherlands

    Background/Purpose: Dissonant perceptions of disease activity between rheumatoid arthritis (RA) patients and their rheumatologists may influence treatment decisions. The discordance between patient's and physician's global…
  • Abstract Number: 2287 • 2013 ACR/ARHP Annual Meeting

    What Is The Internal Consistency Of The Disease Activity Score (DAS)-28 In Rheumatoid Arthritis Patients Treated In a Real–World Setting?

    Andrew Chow1, J. Carter Thorne2, Regan Arendse3, Dalton E. Sholter4, Denis Choquette5, Isabelle Fortin6, Boulos Haraoui5,7, Emmanouil Rampakakis8,9, John S. Sampalis8,9, Francois Nantel10, Allen J. Lehman11, May Shawi12 and Susan M. Otawa11, 1University of Toronto, McMaster University, Credit Valley Rheumatology, Mississauga, ON, Canada, 2Southlake Regional Health Centre, Newmarket, ON, Canada, 3University of Saskatchewan, Saskatoon, SK, Canada, 4Rheumatology Associates, Edmonton, AB, Canada, 5Rheumatology, Institut de rhumatologie de Montréal (IRM), Montréal, QC, Canada, 6Centre de rhumatologie de l'est du Québec (CREQ), Rimouski, QC, Canada, 7Department of Medicine, Centre Hospitalier de l’Université de Montréal, Montréal, QC, Canada, 8JSS Medical Research, Montreal, QC, Canada, 9Jewish General Hospital, McGill University, Montreal, QC, Canada, 10Janssen Inc., Toronto, ON, Canada, 11Medical Affairs, Janssen Inc., Toronto, ON, Canada, 12Medical Affairs, Janssen Canada Inc, Toronto, ON, Canada

    Background/Purpose: The DAS-28 is used in clinical decision making and research as an outcome assessment for patients with RA. The tool measures clinical, patient centric…
  • Abstract Number: 2239 • 2013 ACR/ARHP Annual Meeting

    Validation Of a Patient Reported Experience Measure In Patients With Rheumatoid Arthritis

    Marwan Bukhari1, Peter Jones2, Ifeanyi Sargeant3, Maureen Cox4, Alison Elliott5, Suzanne Bullock6, Anne O'Brien2 and Ailsa Bosworth7, 1Department of Rheumatology, Royal Lancaster Infirmary, Lancaster, United Kingdom, 2Keele University, Keele, United Kingdom, 3IS medical communications, Stafford, United Kingdom, 4Nuffield Orthopaedic centre, Oxford, United Kingdom, 5Roche Pharmaceuticals, Welwyn Garden City, United Kingdom, 6Lancaster University, Lancaster, United Kingdom, 7National Rheumatoid Arthritis Society, Maidenhead, United Kingdom

    Background/Purpose:   Improving patient experience is important in all diseases, but most important in patients with chronic rheumatic diseases like rheumatoid arthritis. To date there…
  • Abstract Number: 1972 • 2013 ACR/ARHP Annual Meeting

    Erosion Case Definition and Scoring Reliability Exercise Using a New Outcome Measurement Tool, High-Resolution Peripheral Quantitative Computed Tomography, In Rheumatoid Arthritis

    Cheryl Barnabe1, Dominique Toepfer2, Hubert Marotte3, Ellen-Margrethe Hauge4, Andrea Scharmga5, Roland Kocijan6, Sebastian Kraus7, Kresten K. Keller4, Joost de Jong8, Jeroen Williams8 and Stephanie Finzel7, 1Medicine, Community Health Sciences, University of Calgary, Calgary, AB, Canada, 2Institute of Medical Physics, University of Erlangen-Nuremberg, Erlangen, Germany, 3Rheumatology Department, University Hospital of Saint-Étienne, Inserm U1059, Saint-Etienne, France, 4Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark, 5Internal Medicine, Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, 6Academic Teaching Hospital of Medical University Vienna, Vienna, Austria, 7Dept of Medicine 3, Rheumatology and Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, 8Maastricht University, Maastricht, Netherlands

    Background/Purpose: High-resolution peripheral quantitative computed tomography (HR-pQCT) is a novel imaging instrument for bony damage in rheumatoid arthritis (RA). Agreement on a case definition for…
  • Abstract Number: 1973 • 2013 ACR/ARHP Annual Meeting

    Importance Of Hand Positioning In 3D Joint Space Morphology Assessment

    Stephanie Boutroy1, Elodie Hirschenhahn1, Emile Youssof2, Hervé Locrelle2, Thierry Thomas2, Roland Chapurlat3 and Hubert Marotte2, 1INSERM U1033 and University of Lyon, Hôpital Edouard Herriot, Lyon, France, 2INSERM U1059 and University Hospital, Hôpital Nord, Saint-Etienne, France, 3INSERM UMR 1033 and University of Lyon, Hôpital Edouard Herriot, Lyon, France

    Background/Purpose: Precise quantification of joint space morphology (JSM) is an important factor for early diagnosis and monitoring of disease activity and therapeutic responses in rheumatoid…
  • Abstract Number: 769 • 2012 ACR/ARHP Annual Meeting

    2010 ACR/EULAR Rheumatoid Arthritis Classification Criteria Predicts Radiogical, but Not Clinical Outcomes At 18 Months Into Disease in a Canadian Early Arthritis Cohort

    Ariel Masetto1, Arthur J. Fernandes2, Patrick Liang3, Pierre Cossette4 and Gilles Boire5, 1Rheumatology, CHUS, Fleurimont, QC, Canada, 2Rheumatology Division, Universite de Sherbrooke, Sherbrooke N, Canada, 3Rheumatology Division, CHUS, Sherbrooke, QC, Canada, 4Internal Medicine Departement, Centre Hospitalier Universitaire de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, Canada, 5Rheumatology Division, Centre Hospitalier Universitaire de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, Canada

    Background/Purpose: The potential of the 2010 ACR/EULAR rheumatoid arthritis (RA) classification criteria to discriminate early arthritis patients according to their clinical and radiological outcomes needs…
  • Abstract Number: 495 • 2012 ACR/ARHP Annual Meeting

    Comparison of Discontinuation Rates by Biologic Since 1998 in US Patients with Rheumatoid Arthritis

    Sofia Ramiro1, Frederick Wolfe2, David J. Harrison3, George Joseph3, David H. Collier3, Désirée van der Heijde4, Robert Landewé5 and Kaleb Michaud6, 1Clinical Immunology & Rheumatology, Academic Medical Center, University of Amsterdam, The Netherlands and Hospital Garcia de Orta, Almada, Portugal, 2National Data Bank for Rheumatic Diseases, Wichita, KS, 3Amgen Inc., Thousand Oaks, CA, 4Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 5Clinical Immunology & Rheumatology, Academic Medical Center, University of Amsterdam and Atrium Medical Center, Heerlen, Netherlands, 6Rheumatology, National Data Bank for Rheumatic Diseases & University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Since discontinuation may be a surrogate for ineffectiveness, we measured rates and reasons for biologic discontinuation in a real-world setting. Methods: From 1998 to…
  • Abstract Number: 421 • 2012 ACR/ARHP Annual Meeting

    Rheumatoid Factor, Not Antibodies to Citrullinated Proteins, Are Associated with High Disease Activity

    Josef S. Smolen1, Farideh Alasti2 and Daniel Aletaha3, 1Medical University of Vienna and Hietzing Hospital, Vienna, Austria, 2Department of Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, 3Department of Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria

    Background/Purpose: Autoantibodies in general, and rheumatoid factor (RF) and anti-citrullinated peptide antibodies (ACPA) in particular, are a hallmark of RA. After their characterization, ACPA have…
  • Abstract Number: 391 • 2012 ACR/ARHP Annual Meeting

    DAS28 Is Not a Sufficient Disease Activity Measure for Obese Rheumatoid Arthritis Patients – Don’t Leave the Feet Behind

    Vikram Garg1, Paul Maranian2, Mihaela B. Taylor3, Harold E. Paulus4, David Elashoff5 and Veena K. Ranganath6, 1Division of Rheumatology, UCLA David Geffen School of Medicine, VA Greater Los Angeles Healthcare System, Los Angeles, CA, 2Division of Rheumatology, UCLA Medical School, Los Angeles, CA, 3Rheumatology, University of California Los Angeles, Los Angeles, CA, 4Medicine-Rheumatology, UCLA David Geffen School of Medicine, Los Angeles, CA, 5Departments of Biostatistics and Medicine, University of California, Los Angeles, Los Angeles, CA, 6Medicine/Rheumatology, University of California, Los Angeles, Western Consortium of Practicing Rheumatologists, Los Angeles, CA

    Background/Purpose: Current literature suggests that obesity impacts disease activity in rheumatoid arthritis (RA) and the incidence of obesity is on the rise. The objective of…
  • Abstract Number: 398 • 2012 ACR/ARHP Annual Meeting

    Basal Metabolic Rate As an Indicator of Rheumatoid Arthritis Disease Activity and Predictor of Remission

    Heather Jones1, Annette Szumski2 and Andrew S. Koenig3, 1Pfizer Inc., Collegeville, PA, 2Specialty Care, Pfizer Inc., Collegeville, PA, 3Specialty Care Business Unit, Pfizer Inc., Collegeville, PA

    Background/Purpose: The role of body mass index (BMI) in rheumatoid arthritis (RA) disease activity and response to treatment has been difficult to determine.1 As a…
  • Abstract Number: 2609 • 2012 ACR/ARHP Annual Meeting

    Construct and Criterion Validity of Several Proposed DAS28 Based Rheumatoid Arthritis Flare Criteria: A Cohort Validation Study

    Aatke van der Maas1, Elisabeth Lie2, Robin Christensen3, Ernest Choy4, Yaël A. de Man5, Piet L.C.M. van Riel6, Thasia G. Woodworth7 and Alfons A. den Broeder1, 1Rheumatology, Sint Maartenskliniek, Nijmegen, Netherlands, 2Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 3Department of Rheumatology, Musculoskeletal Statistics Unit, The Parker Institute, Copenhagen University Hospital, Copenhagen, Denmark, 4Section of Rheumatology, Cardiff University School of Medicine, Cardiff, United Kingdom, 5Rheumatology, Erasmus Medical Centre, Rotterdam, Netherlands, 6Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, 7Medicine, Division of Rheumatology, Visiting Clinical Researcher, Geffen School of Medicine, UCLA, Los Angeles, CA

    Background/Purpose: To enable consistent assessment of impact of tapering, withdrawal and dose optimization strategies, there is an increasing need for validated measures of flare in…
  • Abstract Number: 2134 • 2012 ACR/ARHP Annual Meeting

    The Changed Prognosis of Patients with Early Rheumatoid Arthritis

    Karin Britsemmer1 and Dirkjan van Schaardenburg2, 1Rheumatology, Jan van Breemen Research Institute / Reade, Amsterdam, Netherlands, 2Rheumatology, Jan van Breemen Research Institute | Reade, Amsterdam, Netherlands

    The Changed Prognosis of Patients with Early Rheumatoid Arthritis Background/Purpose: The treatment of rheumatoid arthritis (RA) has changed greatly during the past fifteen to twenty…
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