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Abstracts tagged "outcome measures and rheumatoid arthritis (RA)"

  • Abstract Number: 2370 • 2016 ACR/ARHP Annual Meeting

    Factors Affecting Interval Changes in Perceived Fatigue over Five Years in Patients with Rheumatoid Arthritis Compared with Osteoarthritis

    Simon Stebbings1,2, Gareth Treharne3, J. Haxby Abbott4 and Andrew Gray5, 1Dunedin Hospital, Department of Rheumatology, Dunedin, New Zealand, 2Department of Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand, 3Psychology, University of Otago, Dunedin, New Zealand, 4Centre for Musculoskeletal Outcomes Research, Department of Surgical Sciences, University of Otago, Dunedin, New Zealand, 5Department of Preventive and Social Medicine, University of Otago, Dunedin, New Zealand

    Background/Purpose: In a previous cross-sectional study we noted higher fatigue levels in patients with advanced lower limb OA compared with RA, and identified differences in…
  • Abstract Number: 3192 • 2016 ACR/ARHP Annual Meeting

    Influence of Temperature and Humidity on Disease Activity in Rheumatoid Arthritis

    Peter Mandl1, Farideh Alasti1, Rainer Kaltenberger2, Thomas Krennert2, Gabriela Supp1, Uriel Landesmann1, Josef S. Smolen3 and Daniel Aletaha4, 1Department of Internal Medicine III; Division of Rheumatology, Medical University Vienna, Vienna, Austria, 2Central Institute for Meteorology and Geodynamics, Vienna, Austria, 3Department of Internal Medicine 3, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, 4Department of Internal Medicine 3, Medical University of Vienna, Vienna, Austria

    Background/Purpose: To evaluate whether meteorological parameters influence pain and disease activity in patients with rheumatoid arthritis (RA). Methods: We assessed correlations between individual meteorological variables…
  • Abstract Number: 476 • 2015 ACR/ARHP Annual Meeting

    Clinical Disease Activity Measures Change Substantially and Irregularly over Time in Individual Rheumatoid Arthritis Patients Considered to be in Steady State

    Ole Rintek Madsen1,2 and Emilie Lund Egsmose3, 1Department of Reumatology/C, Copenhagen University Hospital Gentofte, Hellerup, Denmark, 2The DANBIO registry, Copenhagen University Hospital Glostrup Rigshospitalet, Glostrup, Denmark, 3Department of Rheumatology/C, Copenhagen University Hospital Gentofte, Hellerup, Denmark

    Background/Purpose: Assessment of clinical markers of disease activity is routine in monitoring patients with rheumatoid arthritis (RA) in daily practice. Changes in clinical measures may…
  • Abstract Number: 1218 • 2015 ACR/ARHP Annual Meeting

    Higher Education Is Associated with a Better Rheumatoid Arthritis Outcome Concerning Pain and Function but Not Disease Activity: Results from Swedish Registers

    Xia Jiang1, Maria Sandberg2, Saedis Saevarsdottir3, Lars Alfredsson4, Lars Klareskog5 and Camilla Bengtsson6, 1Karolinska Institutet, Stockholm, Sweden, 2Unit of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Karolinska Institutet, Stockholm, Sweden, 3Rheumatology Unit, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden, 4Unit of Cardiovascular Epidemiology, Institute of Enviornmental Medicine, Karolinska Institutet, Karolinska Institutet, Stockholm, Sweden, 5Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden, 6The Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden

    Background/Purpose: To investigate the influence of education (achieving university/college degree (high) or not (low)) on the outcomes of early RA, in terms of disease activity,…
  • Abstract Number: 1304 • 2015 ACR/ARHP Annual Meeting

    Studying MR-Detected Inflammation in Symptom-Free Persons from the General Population to Generate Ramris-Based Reference Values

    L. Mangnus1, H.W. van Steenbergen2, M. Reijnierse3 and A.H.M. van der Helm- van Mil1, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Leiden University Medical Center, Leiden, Netherlands, 3Radiology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: It is recommended by an EULAR imaging taskforce that MR-detected inflammation is useful in the diagnostic process of Rheumatoid Arthritis. This recommendation is based…
  • Abstract Number: 1305 • 2015 ACR/ARHP Annual Meeting

    Prevalence of MR-Detected Ramris-Defined Erosions in the General Population

    L. Mangnus1, H.W. van Steenbergen2, M. Reijnierse3 and A.H.M. van der Helm- van Mil1, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Leiden University Medical Center, Leiden, Netherlands, 3Radiology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: The diagnostic value of Magnetic Resonance (MR) imaging for Rheumatoid Arthritis (RA) is undetermined. The main value of MR is its sensitive depiction of…
  • Abstract Number: 1678 • 2015 ACR/ARHP Annual Meeting

    Does the Level of Disease Control Achieved with Biologics Influence Overall Costs for Health Care and Work Loss in RA?

    Jonas K Eriksson1, Martin Neovius2, Johan Askling3 and ARTIS study group, 1Clinical Epidemiology Unit, Dept of Medicine, Karolinska Institutet, Stockholm, Sweden, 2Clinical Epidemiology Unit, Karolinska Institutet, Stockholm, Sweden, 3Rheumatology Unit, Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden

    Background/Purpose: Numerous studies have modeled whether biologic drugs are good value for money in the treatment of RA, in terms of reducing health care use…
  • Abstract Number: 2603 • 2015 ACR/ARHP Annual Meeting

    What Is the Variability of HAQ over Time in Patients with Rheumatoid Arthritis Treated with Anti-TNF?

    Regan Arendse1, Boulos Haraoui2, Denis Choquette3, John Kelsall4, Philip Baer5, Dalton Sholter6, William G. Bensen7, Mary J. Bell8, Michelle Teo9, Emmanouil Rampakakis10, Eliofotisti Psaradellis11, Brendan Osborne12, Cathy Tkaczyk12, Karina Maslova13, Francois Nantel14 and Allen J Lehman13, 1University of Saskatchewan, Saskatoon, SK, Canada, 2Institut de Rhumatologie de Montréal and University of Montreal, Montreal, QC, Canada, 3Rheumatology Department, Institut de Rhumatologie de Montréal and University of Montreal, Montreal, QC, Canada, 4Mary Pack Arthritis Centre, Vancouver, Vancouver, BC, Canada, 5Section on Rheumatology, Ontario Medical Association/Journal of the Canadian Rheumatology Association, Toronto, ON, Canada, 6Rheumatology Associates, Edmonton, AB, Canada, 7St Joseph's Healthcare Hamilton, Hamilton, ON, Canada, 8Rheum Div, Sunnybrook Health Sciences Centre/University of Toronto, Toronto, ON, Canada, 9Rheumatology, Penticton Regional Hospital, Penticton, BC, Canada, 10JSS Medical Research, St-Laurent, QC, Canada, 11JSS Medical Research, Montreal, QC, Canada, 12Medical Affairs, Janssen Inc., Toronto, ON, Canada, 13Janssen Inc., Toronto, ON, Canada, 1419 Green belt Dr, Janssen Inc., Toronto, ON, Canada

    Background/Purpose : The Health Assessment Questionnaire (HAQ) remains the gold standard for measuring patient-reported functional status in rheumatoid arthritis (RA) and is included among the…
  • Abstract Number: 2628 • 2015 ACR/ARHP Annual Meeting

    Identifying Anxiety and Depression Among Rheumatoid Arthritis Patients Using the Multidimensional Health Assessment Questionnaire

    Naoto Yokogawa1, Tetsuji Kaneko2, Yoshiki Nagai1, Takahiro Nunokawa3, Toshioki Sawaki3, Katsuaki Shiroto3, Kota Shimada3 and Shoji Sugii3, 1Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center, Tokyo, Japan, 2Division of Clinical Research Support Center, Tokyo Metropolitan Children’s Medical Center, Fuchu, Japan, 3Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center, Fuchu, Japan

    Background/Purpose: The Multidimensional Health Assessment Questionnaire (MDHAQ) was designed to assess quality of life impairment including psychological distress in rheumatoid arthritis (RA) patients. In addition…
  • Abstract Number: 3258 • 2015 ACR/ARHP Annual Meeting

    Different Perception of Disease Activity in Multimorbid Rheumatoid Arthritis Patients

    Helga Radner1,2, Kazuki Yoshida1,3, Sara K. Tedeschi4, M Frits5, C Iannaccone6, N Shadick7, Michael Weinblatt1, Daniel Aletaha8, Josef S. Smolen9 and Daniel H. Solomon10, 1Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 2Department of Internal Medicine III; Division of Rheumatology, Medical University of Vienna, Vienna, Austria, 3Department of Epidemiology, Harvard School of Public Health, Boston, MA, 4Rheumatology, Brigham & Women's Hospital, Boston, MA, 5Division of Rheumatology, Brigham and Women's Hospital, Boston, MA, 6Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, Boston, MA, 7Division of Rheumatology, Immunology & Allergy, Brigham and Women's Hosp, Boston, MA, 8Rheumatology, Medical University Vienna, Vienna, Austria, 9Dept of Medicine 3, Division of Rheumatology, Medical Univ Vienna, Vienna, Austria, 10Rheumatology, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: The patient rating of global rheumatoid arthritis (RA) disease activity (PtGA) is a key variable in composite measures of disease activity as well as…
  • Abstract Number: 1522 • 2014 ACR/ARHP Annual Meeting

    Impact of Sarilumab on Health Related Quality of Life (HRQoL),  Fatigue, and Sleep in Rheumatoid Arthritis Patients at Week 24 – Results of a Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study

    Vibeke Strand1, George Joseph2, Hubert van Hoogstraten2, Chieh-I Chen3, Chungpeng Fan2, Paulo Carita4, Neil Graham3, Tanya Momtahen2 and Mark C Genovese5, 1Biopharmaceutical Consultant, Portola Valley, CA, 2Sanofi, Bridgewater, NJ, 3Regeneron Pharmaceuticals, Inc., Tarrytown, NY, 4Sanofi, Chilly-Mazarin, France, 5Division of Immunology and Rheumatology, Stanford University Medical Center, Palo Alto, CA

    Background/Purpose: Sarilumab, a fully human monoclonal antibody directed against the IL-6 receptor, demonstrated efficacy in the phase 3 part of the RA-MOBILITY study (NCT01061736) in…
  • Abstract Number: 356 • 2014 ACR/ARHP Annual Meeting

    The Rheumatoid Arthritis Impact of Disease Score Is Associated with Disease Activity By Clinical, Laboratory and Ultrasonographic Measures: Validation in an inception Cohort of DMARD naïve Patients with Rheumatoid Arthritis

    Lena Bugge Nordberg1, Elisabeth Lie2, Anna-Birgitte Aga1, Marthe Thoresen Maehlen3, Inge Olsen C4, Till Uhlig4, Tore K. Kvien4, Espen A. Haavardsholm5 and the Arctic study Group5, 1Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 2Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 3Department of rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 4Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 5Diakonhjemmet Hospital, Oslo, Norway

     Background/Purpose: The Rheumatoid arthritis impact of disease (RAID) score is a relatively new patient-derived composite score assessing the seven most important domains of the impact…
  • Abstract Number: 2402 • 2014 ACR/ARHP Annual Meeting

    Evaluation of Perceived Self-Efficacy, Learned Helplessness and Functional Capacity in Patients with Rheumatoid Arthritis

    Facundo Vergara1, Emmanuel Bertiller2, Celeste Orozco3, Javier Rosa1, Erika Catay1, Maria de los Angeles Gallardo4, Emilce Schneeberger5, Maria Victoria Garcia1, Gustavo Citera6, Marcos G. Rosemffet7, Mirtha Sabelli1 and Enrique R. Soriano8, 1Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 2Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 3Instituto Rehabilitacion Psicofisica, Buenos Aires, Argentina, 4Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, BUENOS AIRES, Argentina, 5Instituto de Rehabilitacion Psicofisica, Buenos Aires, Argentina, 6Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 7Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 8Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Buenos Aires, Argentina

    Background/Purpose:  Rheumatoid Arthritis (RA) is an inflammatory chronic disease that involves cognitive and emotional aspects of patients, from the beginning of diagnosis. One relevant cognitive…
  • Abstract Number: 2136 • 2014 ACR/ARHP Annual Meeting

    Rheumatoid Arthritis Erosion Detection and Measurement in Longitudinal Datasets Using High-Resolution Peripheral Quantitative Computed Tomography

    Stephanie Finzel1, Cheryl Barnabe2, Kathryn Stok3, A. Scharmga4, Andrew J. Burghardt5, Ellen-Margrethe Hauge6, Hubert Marotte7, Stephanie Boutroy8, Klaus Engelke9, Dominique Toepfer10, Sebastian Kraus11, Roland Kocijan12, Xiaojuan Li13 and J. de Jong4, 1Dept of Medicine 3, Rheumatology and Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, 2Division of Rheumatology, University of Calgary, Calgary, AB, Canada, 3Hpi F 26, Worfgang-Paul Str. 1, ETH Zurich Institute for Biomechanics, Zurich, Switzerland, 4Internal Medicine, Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, 5Department of Radiology & Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, UCSF, San Francisco, CA, 6Reumatologisk Afdeling, Aarhus Universitetshospital, Aarhus C, Denmark, 7Rheumatology, University Hospital of Saint Etienne, Saint Etienne, France, 8INSERM U1033 and University of Lyon, Hôpital Edouard Herriot, Lyon, France, 9Henkestr. 91, Institute of Medcial Physics Synarc, Hamburg, Germany, 10Institute of Medical Physics, University of Erlangen-Nuremberg, Erlangen, Germany, 11Internal Medicine 3, Rheumatology and Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, 12Medical Department II, St. Vincent Hospital, Vienna, Austria, 13Department of Radiology and Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, UCSF, San Francisco, CA

    Background/Purpose An operational case definition for identification of erosions imaged by HR-pQCT was achieved and tested in a first reliability exercise (RELEX-1) using cross-sectional data.…
  • Abstract Number: 2052 • 2014 ACR/ARHP Annual Meeting

    Foot and Ankle Characteristics Associated with Falls in Adults with Rheumatoid Arthritis

    Angela Brenton-Rule1, Nicola Dalbeth2, Priya Parmer3, Sandra Bassett4, Hylton B. Menz5 and Keith Rome6, 1Podiatry, AUT University, Auckland, New Zealand, 2Department of Medicine, University of Auckland, Auckland, New Zealand, 3Biostatistics, AUT University, Auckland, New Zealand, 4AUT University, Auckland, New Zealand, 5Lower Extremity and Gait Studies Program, La Trobe University, Bundoora, Victoria 3086, Australia, 690 Akoranga Drive, AUT University, Auckland, New Zealand

    Background/Purpose People with rheumatoid arthritis (RA) have an increased risk of falls. The consequences of falls can be devastating including loss of confidence and independence,…
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