ACR Meeting Abstracts

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Abstracts tagged "osteoprotegerin"

  • Abstract Number: 2459 • 2014 ACR/ARHP Annual Meeting

    Osteoprotegerin CGA Haplotype Protection Against Cerebrovascular Complications in Anti-CCP Negative Patients with Rheumatoid Arthritis

    Fernanda Genre1, Raquel López-Mejías1, Mercedes García-Bermúdez2, Santos Castañeda3, Carlos González-Juanatey4, Javier Llorca5, Alfonso Corrales1, Begoña Ubilla1, Jose A. Miranda-Filloy6, Encarnación Amigo6, Trinitario Pina Murcia1, Carmen Gómez-Vaquero7, Luis Rodriguez-Rodriguez8, Benjamin Fernández Gutierrez8, Alejandro Balsa9, Dora Pascual-Salcedo9, Francisco Javier López-Longo10, Patricia Carreira11, Ricardo Blanco12, Isidoro González-Alvaro13, Javier Martin14 and Miguel A González-Gay1, 1Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, IDIVAL, Santander, Spain, 2Instituto de Parasitología y Biomedicina López-Neyra, IPBLN-CSIC, Granada, Spain, 3Rheumatology, Hospital Universitario de La Princesa, IISP, Madrid, Spain, 4Hospital Universitario Lucus Augusti. Cardiology Division, Lugo, Spain, 5Department of Epidemiology and Computational Biology, School of Medicine, University of Cantabria, and CIBER Epidemiología y Salud Pública (CIBERESP), IDIVAL, Santander, Spain, 6Hospital Universitario Lucus Augusti, Rheumatology Division, Lugo, Spain, 7Rheumatology Service, Hospital Universitari de Bellvitge - IDIBELL, Barcelona, Spain, 8Hospital Clínico San Carlos, Department of Rheumatology, Madrid, Spain, 9Hospital Universitario La Paz, Department of Rheumatology, Madrid, Spain, 10Hospital General Universitario Gregorio Marañón, Department of Rheumatology, Madrid, Spain, 11Hospital Universitario 12 de Octubre, Department of Rheumatology, Madrid, Spain, 12Hospital Marques de Valdecilla, Santander, Spain, 13Rheumatology, Hospital Universitario de La Princesa. IIS La Princesa, Madrid, Spain, 14Immunology, Instituto de Parasitología y Biomedicina López-Neyra, IPBLN-CSIC, Armilla (Granada), Spain

    Background/Purpose: Rheumatoid arthritis is an inflammatory disease with a high incidence of cardiovascular disease due to accelerated atherosclerosis. Osteoprotegerin (OPG) has been associated with an…
  • Abstract Number: 412 • 2014 ACR/ARHP Annual Meeting

    Determinants of Radiological Progression in Rheumatoid Arthritis: Relationship with Serum Levels of OPG, RANKL and DKK-1

    Carmen Gómez-Vaquero1, Irene Martín-Esteve1, Jose Ivorra2, Jose Antonio Narvaez3, Javier Hernandez Gañan3, Pedro Alia4 and Javier Narváez5, 1Rheumatology Service, Hospital Universitari de Bellvitge - IDIBELL, Barcelona, Spain, 2Department of Rheumatology, Hospital Universitario y Politécnico La Fe., Valencia, Spain, 3Radiology Department, Hospital Universitari de Bellvitge - IDIBELL, Barcelona, Spain, 4Clinical Laboratory Service, Hospital Universitari de Bellvitge - IDIBELL, Barcelona, Spain, 5Rheumatology, Hospital Universitario de Bellvitge. Barcelona. Spain, Barcelona, Spain

    Background/Purpose: Osteoprotegerin (OPG), RANKL, and DKK-1 act as regulators of bone resorption and formation. The uncoupling of bone remodelling that occurs in rheumatoid arthritis (RA)…
  • Abstract Number: 395 • 2014 ACR/ARHP Annual Meeting

    Could Osteoprotegerin and TNF-Related Apoptosis-Inducing Ligand Assessments Help Us to Manage Early Rheumatoid Arthritis? Results from the Espoir Cohort

    Rachel Audo1, Claire I. Daien2, Laura Papon1, Cédric Lukas3, O Vittecoq4, B Combe5 and Jacques Morel6, 1IGMM, CNRS UMR5535, Montpellier, Montpellier, France, 2Department of Rheumatology, Lapeyronie Hospital, Montpellier, France, 3Immuno-Rhumatologie, Hopital Lapeyronie, Montpellier, France, 4Rouen University Hospital & Inserm U905, Rouen, France, 5Immuno-Rhumatologie, Hôpital Lapeyronie, Montpellier, France, 6Department of Rheumatology, Hôpital Lapeyronie, Montpellier, France

    Background/Purpose : TNF-Related Apoptosis Inducing Ligand (TRAIL) is a member of the TNF familly. Its soluble receptor Osteoprotegerin (OPG) also inhibits Receptor activator of nuclear…
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