Abstracts tagged "osteoporosis"

Abstract Number: 0576 • ACR Convergence 2022
Comparative Effectiveness of Osteoporosis (OP) Therapies Among a Population of Postmenopausal (PM) Women in the United States (U.S.)
Min Kim¹, Leah J McGrath², David Pritchard², Peter Samai², Jay Lin¹, Robert Kees Stad³, Leslie Spangler¹, Michele McDermott¹, Brian D Bradbury⁴ and M Alan Brookhart², ¹Amgen, Inc., Thousand Oaks, CA, ²NoviSci, Inc., Durham, NC, ³Amgen Inc., Zug, Switzerland, ⁴Amgen Inc., 1 Amgen Center Drive
Background/Purpose: Although clinical trials evaluating the efficacy of osteoporosis (OP) therapies have shown that denosumab (Dmab) significantly increases bone mineral density at pivotal sites compared…
Abstract Number: 1314 • ACR Convergence 2022
Response Rates for Lumbar Spine, Total Hip, and Femoral Neck Bone Mineral Density with Abaloparatide in Men: Results from the ATOM Study
Ruban Dhaliwal¹, David Kendler², Kenneth Saag³, Steven Ing⁴, Andrea Singer⁵, Robert Adler⁶, Leny Pearman⁷, Yamei Wang⁷ and Bruce Mitlak⁸, ¹SUNY Upstate Medical University, Syracuse, NY, ²University of British Columbia, Vancouver, BC, Canada, ³University of Alabama at Birmingham, Birmingham, AL, ⁴Ohio State University Wexner Medical Center, Colombus, OH, ⁵MedStar Georgetown University Hospital, Washington, DC, ⁶Hunter Holmes McGuire Veterans Affairs Medical Center-Richmond, Richmond, VA, ⁷Radius Health, Inc., Waltham, MA, ⁸Radius Health, Inc, Boston, MA
Background/Purpose: In the Abaloparatide for the Treatment of Men with Osteoporosis (ATOM) study, 12 months of abaloparatide therapy resulted in rapid and significant improvements in…
Abstract Number: 1826 • ACR Convergence 2022
Association of High Uric Acid Levels with Low Bone Mineral Density in Pre- but Not Post-menopausal Women with Rheumatoid Arthritis
Sandra Hermann¹, Andriko Palmowski¹, Bukrhard Muche², Kay-Geert Hermann³, Edgar Wiebe¹ and Frank Buttgereit⁴, ¹Department of Rheumatology and Clinical Immunology, Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, ²Charité University Hospital, CCM, Berlin, Germany, ³Charité - Universitätsmedizin Berlin, Berlin, Germany, ⁴Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin / DRFZ Berlin, Berlin, Germany
Background/Purpose: Uric acid is controversially discussed regarding its effect on bone health. Higher uric acid levels have been associated with higher T-scores and fewer bone…
Abstract Number: 0577 • ACR Convergence 2022
Bone Mineral Density of Radius 1/3 Led to a Better Fracture Prediction When Combined with Spine but Not Hip BMD: Results from the São Paulo Ageing & Health (SPAH) Study
Diogo Domiciano¹, Luana Machado², Valeria Caparbo³, Carolina Teixeira Cidon⁴, Thais Helena Bonini Gorayeb⁴, Maria Aurora Gomes da SIlva⁵, ricardo Manoel de oliveira⁶, camille figueiredo³ and Rosa Pereira³, ¹Hospital das Clinicas, Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ²Hospital das Clinicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ³Bone Metabolism Laboratory, Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ⁴Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ⁵Bone Metabolism Laboratory, Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, ⁶RDO Diagnósticos Médicos, São Paulo, Brazil
Background/Purpose: Bone mineral density (BMD) of the spine or hip are predictors of osteoporotic fracture, but individuals who sustain "osteoporosis-related" fractures frequently have normal BMD…
Abstract Number: 1315 • ACR Convergence 2022
Building Stronger Bones: Optimizing Osteoporosis Screening at a Primary Care Clinic
Rebecca Pietro¹, Shu Min Lao¹ and Geeta Varghese², ¹Mount Sinai Morningside West, New York, NY, ²Ryan Chelsea Clinton Clinic, New York, NY
Background/Purpose: Osteoporosis is a silent disease characterized by low bone mass and deterioration of bone quality, affecting 25% of women.1 The United States Preventive Services…
Abstract Number: 0727 • ACR Convergence 2022
Primary Prevention of Fractures in Osteoporotic Patients in a Southern California Academic Health System
Eugene Looi¹, Gergana Mishkova¹ and Christina Downey², ¹Loma Linda University, Loma Linda, CA, ²Loma Linda University Medical Center, Redlands, CA
Background/Purpose: Osteoporosis (OSP) is common, carries high morbidity, significant cost and remains underrecognized and undertreated by health care providers (1). At a university-based academic health…
Abstract Number: 1317 • ACR Convergence 2022
The Epidemiology of Old versus Young Males Referred for BMD Assessment
Muhammed Aqib Khan¹, Rabie Hamad¹, Hamzah Amin¹ and Marwan Bukhari², ¹Royal Lancaster Infirmary, Lancaster, United Kingdom, ²University Hospitals of Morecambe Bay NHS Trust, Lancaster, United Kingdom
Background/Purpose: Data on osteoporosis in men are scarce. The World Health Organisation's (WHO) definition of a T-score less than 2.5 has only been described for…
Abstract Number: 0734 • ACR Convergence 2022
Comfort Levels and Practice Patterns for Osteoporosis-Related Care Among Persons Living with HIV in Peru: A National Physician Survey
Rebecca Slotkin¹, Camila Lucero Granda Calderón², Diego Cabrera³, Carlos Manuel Benites Villafane⁴, Patricia Jannet Garcia⁵ and Evelyn Hsieh³, ¹Yale University School of Public Health, New Haven, CT, ²Facultad de Medicina Alberto Hurtado de la Universidad Peruana Cayetano Heredia, Lima, Peru, ³Section of Rheumatology, Allergy and Immunology, Yale School of Medicine, New Haven, CT, ⁴Ministerio de Salud, Lima, Peru, ⁵Epidemiology, STD, and HIV Unit, School of Public Health, Universidad Peruana Cayetano Heredia, Lima, Peru
Background/Purpose: As they age, persons living with HIV (PLWH) are at increased risk for osteoporosis due to chronic infection and antiretroviral therapies (ART). In Peru,…
Abstract Number: 1318 • ACR Convergence 2022
Low-Dose Prednisolone (≤5 Mg/d) Is Not Associated with Deleterious Effects on Bone Mineral Density: Baseline Findings in a Cohort of Rheumatic Disease Patients with Prior Glucocorticoid Exposure
Edgar Wiebe¹, Dörte Huscher², Desirée Schaumburg¹, Andriko Palmowski¹, Sandra Hermann¹, Thomas Buttgereit³, Robert Biesen⁴, Gerd Burmester⁵, Yannick Palmowski⁶, Maarten Boers⁷, John Stone⁸, Christian Dejaco⁹ and Frank Buttgereit¹⁰, ¹Department of Rheumatology and Clinical Immunology, Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, ²Institute of Biometry and Clinical Epidemiology, and Berlin Institute of Health, Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, ³Department of Dermatology, Venerology and Allergology, Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, ⁴Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, ⁵Charité University Medicine Berlin, Berlin, Germany, ⁶Spine Department, Center for Musculoskeletal Surgery, Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, ⁷Amsterdam UMC, Vrije Universiteit, Amsterdam, Netherlands, ⁸Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston, MA, ⁹Department of Rheumatology, Hospital of Brunico (SABES-ASDAA), Brunico, Italy, and Department of Rheumatology and Immunology, Medical University of Graz, Graz, Austria, ¹⁰Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin / DRFZ Berlin, Berlin, Germany
Background/Purpose: Inflammatory rheumatic and musculoskeletal diseases (iRMD) are associated with increased systemic bone loss that is mediated by chronic inflammation, treatment with glucocorticoids (GC), and…
Abstract Number: 0889 • ACR Convergence 2022
Serum Adipokines Predict Incident Osteoporotic Fracture in Patients with Rheumatoid Arthritis
Joshua Baker¹, Katherine Wysham², Bryant England³, Punyasha Roul⁴, Aleksander Lenert⁵, Grant Cannon⁶, Brian Sauer⁷, Geoffrey Thiele³ and Ted Mikuls⁸, ¹University of Pennsylvania, Philadelphia, PA, ²VA Puget Sound/University of Washington, Seattle, WA, ³University of Nebraska Medical Center, Omaha, NE, ⁴UNMC, Omaha, NE, ⁵University of Iowa, Iowa City, IA, ⁶Retired, Salt Lake City, UT, ⁷Salt Lake City VA/University of Utah, Salt Lake City, UT, ⁸Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Adipokines are fat and muscle-secreted protein hormones that regulate metabolism. Adiponectin has been associated with fracture in the general population while the role of…
Abstract Number: 1319 • ACR Convergence 2022
Prognostic Utility of Metacarpal Bone Mineral Density Measurement in Patients with Recent-onset Arthritis by Assessment of Radiographic Progression at 2-year Follow Up
Irene Maria Llorente Cubas¹, Ana Maria Fernandez Ortiz², Jesus Alberto Garcia Vadillo¹, Jose ivorra Cortes³, Luis Rodriguez-Rodriguez⁴, Rosario Garcia-Vicuña⁵, Santos Castañeda⁶, Isidoro Gonzalez¹ and Ana M Ortiz¹, ¹Hospital Universitario de La Princesa, Madrid, Spain, ²Hospital Universitario de Badajoz, Badajoz, Spain, ³Hospital Universitario de La Fe, València, Spain, ⁴Instituto de Investigación Sanitaria San Carlos, Rheumatology, Madrid, Spain, ⁵Hospital Universitario de La Princesa, IIS-Princesa, Madrid, Spain, ⁶Division of Rheumatology, Hospital Universitario de La Princesa, IIS-Princesa, Madrid, Spain
Background/Purpose: Rheumatoid arthritis (RA) and osteoporosis (OP) have a complex interplay in terms of pathogenic mechanisms. In this regard, radiogrammetry (DXR) of the hand, a…
Abstract Number: 1276 • ACR Convergence 2022
Bone Density Imaging: Evaluation of Equipment and Process of Care Quality in US Veterans
Karla Miller¹, Melissa Steffen², Kimberly McCoy², Michelle Mengeling², Heather Davila², Shylo Wardyn² and Samantha Solimeo², ¹University of Utah Division of Rheumatology/VA Salt Lake City Health Care, Salt Lake City, UT, ²Iowa City VAMC, Iowa City, IA
Background/Purpose: Osteoporotic fractures contribute to significant morbidity and mortality. Dual-energy x-ray absorptiometry (DXA) is a valuable tool to identify osteoporosis, assess fracture risk, and monitor…
Abstract Number: 1320 • ACR Convergence 2022
Performance of FRAX® Brazil and NOGG Methodology with and Without Bone Mineral Density upon Predicting Fractures on a Community-Dwelling Elderly Population with High Incidence of Osteoporotic Fractures: The São Paulo Ageing and Health (SPAH) Study
Thiago Q Freitas¹, Leonardo F G Olalla¹, Liliam Takayama¹, Valeria Caparbo², camille figueiredo², Luana Machado³, Diogo Domiciano⁴ and Rosa Pereira², ¹University of São Paulo, São Paulo, Brazil, ²Bone Metabolism Laboratory, Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ³Hospital das Clinicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ⁴Hospital das Clinicas, Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
Background/Purpose: SPAH is a prospective cohort of ≥65-year-old community-dwelling elderly with high fracture risk (40.3/1,000 person-years in women and 30.6/1,000 in men for vertebral fractures…
Abstract Number: 1277 • ACR Convergence 2022
Improving Patient Appropriate Osteoporosis Screening with Dual Energy X-ray Absorptiometry Scans in an Academic Internal Medicine Practice
Nithin Pusapati¹, Rebecca Fitzpatrick¹, Manya Gupta¹ and Sonali Khandelwal², ¹Rush University Medical Center, Chicago, IL, ²Rush University, Chicago, IL
Background/Purpose: Nearly 53.6 million people in America have osteoporosis with increasing incidence each year (Brauer, JAMA 2009). Almost 25% of people with a hip fracture…
Abstract Number: 1322 • ACR Convergence 2022
Follow up of Incidentally Noted Vertebral Compression Fractures
Jason Yang¹, Alexia Hwang¹, Megan Brochu², Krista Sabina², Meridith Malysz², Bruce Weinstein³ and Jonathan Cheah¹, ¹UMass Chan Medical School, Worcester, MA, ²UMass Memorial Health, Worcester, MA, ³UMass Memorial Health, UMass Chan Medical School, Worcester, MA
Background/Purpose: Vertebral compression fractures (VCFs) in general represent a clinical diagnosis of osteoporosis, predisposing to an increased risk of additional fractures. However, a significant number…

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