ACR Meeting Abstracts

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Abstracts tagged "osteoporosis"

  • Abstract Number: 2014 • ACR Convergence 2023

    The Role of Orosomucoid 2 in the Regulation of Bone Remodeling by Inhibiting Osteoclastogenesis and Promoting Osteogenesis

    CHONG HYUK CHUNG1, Myeung-Su Lee1 and Chang-hoon Lee2, 1Wonkwang University Hospital, Iksan, South Korea, 2Wonkwang University Hospital, Iksan Jeonbuk, South Korea

    Background/Purpose: Orosomucoid (ORM) is one of the acute phase reactant protein family and is expressed in hepatocytes and secreted into plasma under stress conditions such…
  • Abstract Number: 1999 • ACR Convergence 2023

    One-year Incidence of Clinical Fragility Fractures After Implementing an Osteoporosis Care Protocol in Patients Eligible for Liver Transplantation

    Cristina Rodríguez-Alvear1, Mª Carmen López-González2, Elisabet Perea-Martínez3, Antonio Avilés-Hernández3, Irene Calabuig-Sais1, Maria-Luisa Peral-Garrido4, Pilar Bernabeu-Gonzálvez3, Agustín Martínez-Sanchís1, Joaquim Esteve-Vives3, PALOMA VELA5, Cayetano Miralles Maciá3, Vega Jovani6 and Mariano Andrés1, 1Dr Balmis Alicante General University Hospital-ISABIAL, Alicante, Spain, 2General University Hospital Dr. Balmis, Alacante, Spain, 3General University Hospital Dr. Balmis, Alicante, Spain, 4Vinalopó University Hospital, Novelda, Spain, 5Rheumatology, Hospital General Universitario Alicante, Alicante, Spain, 6Department of Rheumatology, Hospital General Universitario Dr. Balmis, Alicante, Spain

    Background/Purpose: In solid organ transplantation, liver transplants are among those most frequently associated with the development of low bone mass, which occurs in up to…
  • Abstract Number: 2016 • ACR Convergence 2023

    Generation of a Human 3D in Vitro Bone Model That Mimics Glucocorticoid-induced Osteoporosis

    Moritz Pfeiffenberger1, Johannes Plank1, Alexandra Damerau1, Timo Gaber1 and Frank Buttgereit2, 1Charité Universitatsmedizine - Berlin, Berlin, Germany, 2Charité Universitätsmedizin, Dept. Rheumatology, Berlin, Germany

    Background/Purpose: Osteoporosis is a bone disease characterized by low bone mass and changes in bone architecture, leading to pain and reduced mobility in patients. Glucocorticoid-induced…
  • Abstract Number: 2000 • ACR Convergence 2023

    Efficacy of Romosozumab for Glucocorticoid-induced Osteoporosis in Patients with Rheumatic Diseases; A Prospective Study

    Mai Kawazoe1, Kaichi Kaneko2, Shotaro Masuoka3, Soichi yamada3, Zento Yamada3, Sei Muraoka3, Karin Furukawa1, Hiroshi Sato3, Eri Watanabe3, Keiko Koshiba3, Izumi Irita3, Miwa Kanaji3 and Toshihiro Nanki1, 1Division of Rheumatology, Department of Internal Medicine, Toho University School of Medicine, Ota-ku, Japan, 2Division of Rheumatology, Department of Internal Medicine, Toho University Sakura Medical Center, Sakura, Japan, 3Division of Rheumatology, Department of Internal Medicine, Toho University School of Medicine, Tokyo, Japan

    Background/Purpose: Glucocorticoids are widely used to treat a variety of diseases, including rheumatic diseases. Although glucocorticoids improve the outcome for these diseases, various side effects…
  • Abstract Number: 2017 • ACR Convergence 2023

    Lupus Nephritis Is Strongly Associated with Low Bone Mineral Density and Osteoporosis in Patients with Systemic Lupus Erythematosus

    Edgar Wiebe1, Elisa Schilling2, Dörte Huscher3, Andriko Palmowski4, Zhivana Boyadzhieva5, Sandra Hermann1, Burkhard Muche1, Tobias Alexander6, Falk Hiepe5 and Frank Buttgereit1, 1Charité Universitätsmedizin, Dept. Rheumatology, Berlin, Germany, 2Charité Universitätsmedizin Berlin, Dept. Rheumatology, Berlin, Germany, 3Institute of Biometry and Clinical Epidemiology and Berlin Institute of Health, Charité Universitätsmedizin Berlin, Berlin, Germany, 4Charité - Universitätsmedizin Berlin, Berlin, Germany, 5Charité Universitatsmedizine - Berlin, Berlin, Germany, 6Charité Universiätsmedizin Berlin, Dept. Rheumatology, Berlin, Germany

    Background/Purpose: Patients with systemic lupus erythematosus (SLE) are at increased risk for osteoporosis and fragility fractures. This risk is mediated by a variety of factors…
  • Abstract Number: 2001 • ACR Convergence 2023

    Burden of Metabolic Bone Disease in Patients with IgG4-Related Disease with and Without Autoimmune Pancreatitis

    Guy Katz1, Aubree McMahon1, Grace McMahon1, Isha Jha1, Marcy Bolster2, Ana Fernandes1, Zachary Wallace3, Cory Perugino1, John Stone4 and Yasmin Hernandez-Barco1, 1Massachusetts General Hospital, Boston, MA, 2Massachusetts General Hospital, Concord, MA, 3Massachusetts General Hospital, Newton, MA, 4Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Concord, MA

    Background/Purpose: Metabolic bone disease (MBD), including osteopenia and osteoporosis, is common in patients with inflammatory disorders, due to disease factors and glucocorticoid (GC) use, and…
  • Abstract Number: 2018 • ACR Convergence 2023

    Development of an Osteoporosis Treatment Gap Dashboard

    Rulan Lyu1, Patrick O'Brien1, Tracey Wilkie1, Yun Chang1 and Jonathan Cheah2, 1UMass Memorial Health, Worcester, MA, 2UMass Chan Medical School, Shrewsbury, MA

    Background/Purpose: Osteoporosis and the clinical event of fragility fracture is an ever-increasing public health burden. A significant osteoporosis treatment gap remains, whereby individuals with a…
  • Abstract Number: 2002 • ACR Convergence 2023

    Cost-Effectiveness Analysis of Sequential Treatment with Abaloparatide Followed by Alendronate in US Women and Men with Multiple Previous Fractures

    Mickael Hiligsmann1, Stuart Silverman2, Andrea J Singer3, Yamei Wang4, Leny Pearman4, John Caminis4 and Jean-Yves Reginster5, 1Maastricht University, Maastricht, Netherlands, 2Cedars-Sinai Medical Center and UCLA School of Medicine, Los Angeles, CA, 3MedStar Georgetown University Hospital, Washington, DC, 4Radius Health, Inc., Boston, MA, 5University of Liège, Liège, Belgium

    Background/Purpose: Patients with multiple previous fractures are at very high risk of subsequent fractures. Common treatment strategies for these patients include generic alendronate (ALN) monotherapy…
  • Abstract Number: 2025 • ACR Convergence 2023

    Osteoporosis Treatment Attributes and Levels for an Online Decision-Making Tool for Patients: Findings from Adaptive Choice-Based Conjoint Analysis

    Jeffrey Curtis1, Kelly Gavigan2, W. Benjamin Nowell3, David Curtis4, Danielle Ali5, Xiaoyu Liu6, Katherine Makaroff6, Christopher Almario6, Carine Khalil6, So Yung Choi7 and Brennan Spiegel6, 1University of Alabama at Birmingham, Birmingham, AL, 2Global Healthy Living Foundation, Upper Nyack, NY, 3Global Healthy Living Foundation, Nyack, NY, 4Global Healthy Living Foundation, San Francisco, CA, 5Global Healthy Living Foundation, Upper Nayack, NY, 6Cedars-Sinai Center for Outcomes Research and Education (CS-CORE), Los Angeles, CA, 7Biostatistics and Bioinformatics Research Center, Cedars-Sinai Cancer, Los Angeles, CA

    Background/Purpose: Osteoporosis (OP) treatment options have different attributes based on mode of administration, frequency of administration, risks of minor and serious side effects, and effectiveness,…
  • Abstract Number: 2003 • ACR Convergence 2023

    Effects of Abaloparatide on Cortical and Trabecular Compartments by 3D-DXA in Men with Osteoporosis

    Ruban Dhaliwal1, John Boxberger2, Yamei Wang2, Bruce Mitlak2, Ludovic Humbert3 and Neil Binkley4, 1Massachusetts General Hospital, Boston, MA, 2Radius Health, Inc., Boston, MA, 33D-Shaper Medical, Barcelona, Spain, 4University of Wisconsin Osteoporosis Clinical Research Program, Madison, WI

    Background/Purpose: Abaloparatide (ABL) increases BMD in men with osteoporosis. In the Abaloparatide for the Treatment of Men with Osteoporosis (ATOM) trial, DXA-measured BMD change with…
  • Abstract Number: 2123 • ACR Convergence 2023

    Dose Trabecular Bone Score (TBS) Add Predictive Value to Fracture Risk Assessment (FRAX) in Rheumatoid Arthritis?

    Jia-Feng Chen1, Tien-Tsai Cheng2 and Hong-Yo Kang3, 1Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan, 2Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan, 3Graduate Institute of Clinical Medical Sciences, Chang Gung University, College of Medicine, Kaohsiung, Taiwan

    Background/Purpose: Trabecular bone score (TBS) of lumbar spine is a dual X-ray densitometry (DXA)-based tool to evaluate bone microarchitecture, providing information on bone quality in…
  • Abstract Number: 2004 • ACR Convergence 2023

    Bone Health Following Bariatric Surgery: A Single Center Quality Improvement Study

    Andrew Benck, Haley Zimmerman, Amy Trang, Najia Shakoor and Sonali Khandelwal, Rush University, Chicago, IL

    Background/Purpose: Osteoporosis related fractures cause significant morbidity and mortality. Bariatric weight loss surgery is an independent risk factor for osteoporosis. Post-surgery dual energy X-Ray absorptiometry…
  • Abstract Number: 2138 • ACR Convergence 2023

    Frailty Is a Predictor of Incident Osteoporotic Fractures in Veterans with Rheumatoid Arthritis

    K Wysham1, Hannah Brubeck2, Aaron Baraff3, Punyasha Roul4, Namrata Singh5, James Andrews6, Grant Cannon7, Gary Kunkel8, Ted R Mikuls9, Bryant England4, Dolores Shoback10, Patti Katz11, Jose Garcia12, Ariela Orkaby13 and Joshua Baker14, 1VA Puget Sound/University of Washington, Seattle, WA, 2VA Puget Sound Health Care System, Seattle, WA, 3VA Puget Sound Seattle, Seattle, WA, 4University of Nebraska Medical Center, Omaha, NE, 5University of Washington, Bellevue, WA, 6University of Washington, Seattle, WA, 7University of Utah and Salt Lake City VA, Salt Lake City, UT, 8University of Utah, Salt Lake City, UT, 9Division of Rheumatology and Immunology, University of Nebraska Medical Center, Omaha, NE, 10San Francisco VA Medical Center, San Francisco, CA, 11University of California San Francisco, San Rafael, CA, 12VA Puget Sound Healthcare System, Seattle, WA, 13Veterans Affairs Boston Healthcare System & Brigham and Women’s Hospital, Harvard Medical School, Boston, MA; VA Geriatric Research Education and Clinical Center, Boston, MA, 14University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Frailty occurs prematurely in RA. Levels of frailty are higher in Veteran populations than civilians1. Frailty has been shown to predict osteoporotic fractures in…
  • Abstract Number: 2005 • ACR Convergence 2023

    Secondary Prevention of Osteoporosis in Hip Fracture Care for Elderly Patients. Clinical and Functional Profile of Users

    Belén Miguel Ibáñez, Alfonso González Ramírez, Olga Martínez González, Ana Isabel Turrión Nieves, Marta Ibáñez Martínez, Carolina Cristina Chacón Vélez, Laura Blanco Ramis, Manuel Cipriano Martín Martínez, Cristina Hidalgo Calleja, Carlos Alberto Montilla Morales, Susana Gómez Castro, Juan Francisco Blanco Blanco and Carmen Pablos Hernández, University Healthcare Complex of Salamanca, Salamanca, Spain

    Background/Purpose: Osteoporosis is a first-rate problem in an increasingly ageing population. Falls among the elderly are a severe geriatric syndrome with relevant secondary effects. Fractures…
  • Abstract Number: 2429 • ACR Convergence 2023

    Romosozumab versus Denosumab in High-risk Patients Treated with Glucocorticoids: Interim 12-month Results from a Pilot Randomized Controlled Trial

    Chi Chiu Mok1, SAU MEI TSE2, Kar Li Kelly Chan3 and Wai Han Ma1, 1Tuen Mun Hospital, Hong Kong, Hong Kong, 2Tuen Mun Hospital, Hong Kong, China, 3Tuen Mun Hospital, Shatin, China

    Background/Purpose: To compare the efficacy and safety of romozosumab (ROMO) and denosumab (DEN) in high-risk patients treated with glucocorticoids (GCs). Methods: Adult patients (≥18 years)…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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