Abstracts tagged "osteoporosis"

Abstract Number: 0162 • ACR Convergence 2025
Clinical Relevance of Systematic Comorbidity Screening in Autoimmune and Inflammatory Diseases
Martin Michaud, Caroline Arlet, Jean Alain Bournazeau, François de Maupeou, Julie Gaston, Stephanie Mermet, Helene Coulier, Marie Oustalet, Christophe Raspaud, Cédric Maurice, Sophie Recipon, Claire Verplancken, Kim Paricaud and Leonardo Astudillo, Clinique Saint Exupery, TOULOUSE, France
Background/Purpose: Chronic autoimmune and inflammatory diseases are associated with an increased prevalence of various comorbidities, which may impact both prognosis and therapeutic strategies. EULAR recommends…
Abstract Number: 2594 • ACR Convergence 2025
Comparing Immunogenicity Between TVB-009 and Reference Denosumab in Healthy Adults and Participants with Postmenopausal Osteoporosis
Karel Pavelka¹, Frank Schneider², Deepak S³, Bracha Timan⁴, Hadas Barkay⁴ and Anton Buchner², ¹Institute of Rheumatology and Department of Rheumatology, ¹st Faculty of Medicine, Charles University, Prague, Czech Republic, Prague, Czech Republic, ²Teva GmbH, Ulm, Germany, ³Teva Pharma India Private Limited, Bangalore, India, ⁴Teva Pharmaceutical Industries Ltd., Netanya, Israel
Background/Purpose: TVB-009 is being developed as a proposed biosimilar candidate to the reference denosumab. Denosumab is a human IgG2 monoclonal antibody that binds to the…
Abstract Number: 2108 • ACR Convergence 2025
Multidisciplinary Fragility Fracture Management Across Two Coordinated Hospitals: Evaluating Risk Factors, Treatment Approaches, and Long-Term Patient Outcomes in Those With and Without Prior Fractures
César Antonio Egües Dubuc¹, Nerea Alcorta Lorenzo², Esther Laso Lucas³, Carlos Maria Lizasoain Alustiza⁴, Claudia Murillo Erazo³, Gabriela Jimenez Clemente³, Gaspar de La Herran Nuñez⁴, Vicente Lavilla Garcia³, Imanol Gabarain Morcillo⁴, Leire Unanue Pumar⁴, Irene Corcuera Elosegui⁴, Antonio Martin Garcia⁴, Jorge Jesus Cancio Fanlo⁵, Maria Ariztia Sarratea³, Ander Alberdi Arbelaiz⁴, Iñaki Maria Arruabarrena Echeverria³, Elena Zubillaga Azpiroz⁴ and LUIS LOPEZ DOMINGUEZ⁶, ¹Donostia University Hospital, San Sebastián, Pais Vasco, Spain, ²University Hospital Donostia, san sebastian, Spain, ³Matia Hospital, San Sebastian, Pais Vasco, Spain, ⁴Donostia University Hospital, San Sebastian, Pais Vasco, Spain, ⁵Donostia University Hospital, San Sebastian, ⁶Hospital Universitario Donostia, San Sebastian, Spain
Background/Purpose: Our Fracture Coordination Unit operates across two hospitals: University Hospital of Donostia (UHD) and Matía Hospital (MH). Patients with a geriatric profile are transferred…
Abstract Number: 0352 • ACR Convergence 2025
Complication Rates of Typical Hip Fractures, Subtrochanteric Femoral Fractures, and Atypical Femoral Fractures
Marshall Weber¹, William Obremskey², Jared Huling³, Nitya Shah³, Emily Budde⁴, Zhiping Huo⁴, Reside Jacob⁴, Brinda Basida¹, Colton Hoffer¹, Binni Makkar⁵ and Laura Carbone¹, ¹Augusta University, Augusta, GA, ²Vanderbilt University, Nashville, TN, ³University of Minnesota School of Public Health, Minneapolis, MN, ⁴Center of Innovation for Complex Chronic Healthcare, Washington DC, DC, ⁵University of Kentucky, Lexington, KY
Background/Purpose: Atypical femoral fractures (AFFs) are a rare complication of bisphosphonate use and a major reason that drug holidays are recommended following bisphosphonate use. However,…
Abstract Number: 0149 • ACR Convergence 2025
Effect Of Osteoporosis And Opioid Use On Mortality And Unplanned Healthcare Utilization Among Patients With Rheumatoid Arthritis
Viengneesee Thao, Molly Moore Jeffery, Nafisseh Warner and Elena myasoedova, Mayo Clinic, Rochester, MN
Background/Purpose: Patients with rheumatoid arthritis (RA) have a 2-fold increase in risk for osteoporosis compared to the general population. About 30-50% of RA patients experience…
Abstract Number: 2592 • ACR Convergence 2025
Romosozumab and Denosumab Combination Therapy in Postmenopausal Osteoporosis
Giovanni Adami¹, Francesco Pollastri², Angelo Fassio², Camilla Benini², Davide Gatti², Ombretta Viapiana² and Maurizio Rossini², ¹University of Verona, Italy, Verona, Italy, ²University of Verona, Verona, Italy
Background/Purpose: Transition from long-term denosumab to PTH-analogs or romosozumab might expose patients to the risk of the so-called rebound phenomenon. Adding romosozumab to denosumab might…
Abstract Number: 2107 • ACR Convergence 2025
Experience of a Fragility Fracture Coordination Unit Integrated Across Two Hospitals: An Innovative Multidisciplinary Model for Optimizing the Management of Geriatric and Non-Geriatric Patients Beyond Surgery After an Osteoporotic Bone Fragility Fracture
César Antonio Egües Dubuc¹, Esther Laso Lucas², Nerea Alcorta Lorenzo³, Carlos Maria Lizasoain Alustiza⁴, Leire Unanue Pumar⁴, Gabriela Jimenez Clemente², Claudia Murillo Erazo², Vicente Lavilla Garcia², Ander Alberdi Arbelaiz⁴, Elena Zubillaga Azpiroz⁴, Imanol Gabarain Morcillo⁴, Jorge Jesus Cancio Fanlo⁵, Maria Ariztia Sarratea², Iñaki Maria Arruabarrena Echeverria⁴, Gaspar de La Herran Nuñez⁴, Antonio Martin Garcia⁴ and LUIS LOPEZ DOMINGUEZ⁶, ¹Donostia University Hospital, San Sebastián, Pais Vasco, Spain, ²Matia Hospital, San Sebastian, Pais Vasco, Spain, ³University Hospital Donostia, san sebastian, Spain, ⁴Donostia University Hospital, San Sebastian, Pais Vasco, Spain, ⁵Donostia University Hospital, San Sebastian, ⁶Hospital Universitario Donostia, San Sebastian, Spain
Background/Purpose: Fracture Coordination Units typically function within a single hospital using a multidisciplinary approach. Our unit, established in February 2024, pioneers a model coordinating care…
Abstract Number: 0350 • ACR Convergence 2025
Perioperative Evaluation of Blood Tests Including Bone Turnover Markers in Patients Undergoing Surgery for Proximal Femur Fractures
KEN NAKASEKO, KUWANA CITY MEDICAL CENTER, KUWANA, Mie, Japan
Background/Purpose: Osteoporosis treatment is essential to prevent fractures. However, few patients with proximal femur fractures receive osteoporosis treatment before injury. Initiating treatment postoperatively is critical…
Abstract Number: 0064 • ACR Convergence 2025
Sclerostin from marrow adipogenic precursors is essential for bone and joint homeostasis in mice
Tailin He and Yifang Mei, Shenzhen Third People's Hospital, Shenzhen, China (People's Republic)
Background/Purpose: A novel mesenchymal subpopulation known as 'marrow adipogenic lineage precursors' (MALPs) has been identified, characterized by the expression of various adipocyte markers while lacking…
Abstract Number: 2591 • ACR Convergence 2025
Association Between Changes in Bone Quality Parameters and Inflammatory Ratios in Postmenopausal Women Treated With Romosozumab: A Retrospective Observational Study
Montserrat Robustillo-Villarino¹, Andres Zuniga-Vera¹ and Marile Sanabria-Hernández², ¹Department of Rheumatology, Hospital Universitario de la Plana, Vila-real, Castellón, Spain, Vila-real, Castellón, Spain, ²Hospital Universitario de la Plana, Vila-Real, Spain
Background/Purpose: Osteoporosis (OP) is characterized by low bone mass and microarchitectural deterioration, increasing fracture risk. Bone Mineral Density (BMD), T-score, and Trabecular Bone Score (TBS)…
Abstract Number: 2106 • ACR Convergence 2025
Prevalence and Characteristics of Morphometric Vertebral Fractures in the Spanish Population: Data from the OsteoSER Study
Carmen Gomez Vaquero¹, Montserrat Roig Kim², Jordi Fiter Areste³, Marta Domínguez-Álvaro⁴, Luis María Jiménez Liñán⁵, Miguel Bernad⁶, Antonio Álvarez-Cienfuegos⁷, Blanca Correa⁸, Antonio Pascual-Vergara⁹, Alejandra Montero Costa¹⁰, Cristina Momblan Trejo¹¹, Manuel Jiménez Rodríguez¹², María Anadón González¹³, Sara Josefina Barcat Zarate¹⁴, Sara Alvar Pariente¹⁵, Cristina Ruiz Pavón¹⁶, Pedro J. Lacalle Chanivet¹⁷, Balbina Marín de Prada¹⁸, Soledad García Frías¹⁹, Francisco Javier Maestro Saavedra²⁰, Marta Poch i Mora²¹, José Luis Gea González²², Carlota Quiroga Fernández²³, Eduardo Acevedo Martel²⁴ and Enrique González-Dávila²⁵, ¹Hospital Universitari de Bellvitge, ⁰⁸⁹⁰⁷ L'Hospitalet, Spain, ²Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Spain, ³Hospital Universitari Son Espases, Palma de Mallorca, Spain, ⁴Sociedad Española de Reumatología, Madrid, Spain, ⁵Hospital Don Benito-Villanueva, Don Benito, Spain, ⁶Hospital Universitario La Paz, Madrid, Spain, ⁷Hospital Vega Baja, Orihuela, Spain, ⁸Clínica Sanz y Correa, A Coruña, Spain, ⁹Centro de Salud Ronda-Norte y Ronda-Sur, Ronda, Spain, ¹⁰Centro de Salud Fuencarral, Madrid, Spain, ¹¹Centro de Atención Primaria Viladecans Montbaig, Sant Climent de Llobregat, Spain, ¹²Centro de Salud Don Benito Oeste, Don Benito, Spain, ¹³Consultorio de Pedrezuela, Pedrezuela, Spain, ¹⁴Centro de Salud Orihuela ¹-El Rabaloche, Orihuela, Spain, ¹⁵Centro de Salud Malpica, Malpica, Spain, ¹⁶Centro de Salud Ronda-Norte, Ronda, Spain, ¹⁷Centro de Salud de Santa Amalia, Santa Amalia, Spain, ¹⁸Centro de Atención Primaria Ramona Via i Pros, El Prat de Llobregat, Spain, ¹⁹Centro de Salud de Cortes de la Frontera, Cortes de la Frontera, Spain, ²⁰Centro de Salud Elviña Mesoiro, A Coruña, Spain, ²¹Centro de Atención Primaria CAP ¹⁷ de Setembre, El Prat de Llobregat, Spain, ²²Centro de Salud de Benejúzar, Benezujar, Spain, ²³Centro de Salud Os Mallos, A Coruña, Spain, ²⁴Centro de Salud Ronda-Sur Santa Bárbara, Ronda, Spain, ²⁵Departamento de Matemáticas. Universidad de La Laguna, Tenerife, Spain
Background/Purpose: Most vertebral fractures (VFs) are asymptomatic. Vertebral Fracture Assessment (VFA) using DXA is a low-radiation method to detect morphometric vertebral fractures (MVFs). This study…
Abstract Number: 0351 • ACR Convergence 2025
Experience with romosozumab in women with osteoporosis at high risk of fracture in real-world clinical practice
MARIA DEL CARMEN ORTEGA DE LA O¹, Laura Gonzalez Hombrado², Marina Salido Olivares³, Carolina Marin⁴, Angel Aragon⁵, Celia arconada⁶, Maria Carmen Ortega de la O⁷, Alvaro Garcia⁸, elisabeth Castañeda⁹, Patricia Castro Perez¹⁰, alberto diaz Oca¹¹ and Eva Andres Esteban¹², ¹HOSPITAL UNIVERSITARIO GETAFE, GETAFE, Madrid, Spain, ²Hospital Universitario del Tajo, Aranjuez (MADRID), Madrid, Spain, ³Hospital Clinico San Carlos, Madrid, Madrid, Spain, ⁴Hospital Infanta Leonor, Madrid, Madrid, Spain, ⁵Hospital Universitario Quironsalud Madrid, Pozuelo de Alarcon, Madrid, Spain, ⁶Hospital universitario de Getafe, Getafe, Madrid, Spain, ⁷Hospital Universitario Getafe, Madrid, Madrid, Spain, ⁸Hospital Universitario del Tajo, Aranjuez, Madrid, Spain, ⁹Hospital Universitario Infanta Sofía, Madrid, Madrid, Spain, ¹⁰Hospital de Getafe, Madrid, Madrid, Spain, ¹¹Hospital de Fuenlabrada, Fuenlabrada, Madrid, Spain, ¹²Universidad Rey Juan Carlos, Fuenlabrada, Spain
Background/Purpose: Romosozumab (RMZ) is a recently approved dual-acting drug which has been shown to reduce fracture risk in patients with osteoporosis (OP) in clinical trials.…
Abstract Number: 2114 • ACR Convergence 2025
Development of a Fracture Prediction Model for Patients Aging with HIV
Evelyn Hsieh¹, Terrence E. Murphy², Baylah Tessier-Sherman³, Linda Leo-Summers³, Farah Kidwai-Khan⁴, Samah Fodeh⁵, Rixin Wang⁶, Barbara Gulanski³, Michael T. Yin⁷, Melissa Skanderson⁸, Cynthia Brandt⁹, Amy C. Justice⁴ and Julie Womack¹⁰, ¹Section of Rheumatology, Allergy and Immunology, Yale School of Medicine / VA Connecticut Healthcare System, New Haven, CT, ²Department of Public Health Sciences, Pennsylvania State University College of Medicine, Hershey, PA, ³Department of Internal Medicine, Yale School of Medicine, New Haven, CT, ⁴Department of Internal Medicine, Yale School of Medicine / VA Connecticut Healthcare System, New Haven, CT, ⁵Department of Emergency Medicine, Yale School of Medicine, New Haven, CT, ⁶Department of Biomedical Informatics & Data Science, Yale School of Medicine, New Haven, CT, ⁷Columbia University Irving Medical Center, New York, NY, ⁸VA Connecticut Healthcare System, West Haven, CT, ⁹Department of Biomedical Informatics & Data Science, Yale School of Medicine / VA Connecticut Healthcare System, New Haven, CT, ¹⁰Yale School of Nursing / VA Connecticut Healthcare System, Orange, CT
Background/Purpose: Fragility fractures are a critical outcome for people ageing with HIV (PAH). Studies demonstrate higher prevalence, incidence, and earlier onset than for the general…
Abstract Number: 2566 • ACR Convergence 2025
Using Abdominal CT-Derived Bone Mineral Density and Psoas Volume for Opportunistic Osteoporosis Screening and Fracture Risk Assessment
Ye Liu¹, Hongke Wu¹, Amy Mudano², Omar Safarini¹, John Eddins¹, Carlos Cardenas¹, Lesley Jackson¹, Jeffrey Curtis³ and Steven Rothenberg¹, ¹University of Alabama at Birmingham, Birmingham, AL, ²Foundation for Advancing Science, Technology, Education and Research (FASTER), Hoover, AL, ³Foundation for Advancing Science, Technology, Education and Research, Birmingham, AL
Background/Purpose: Osteoporosis (OP) is assessed by dual-energy X-ray absorptiometry (DXA) for bone mineral density (BMD). Computed tomography (CT) offers an alternative for “opportunistic” screening. This…
Abstract Number: 1997 • ACR Convergence 2025
Bone health in patients with gout using real-world U.S. data
Emily Holladay¹, Alexis Woods², Fenglong Xie³, Jingyi Zhang¹, Angelo Gaffo⁴, Jeffrey Curtis⁵ and Brian Lamoreaux⁶, ¹University of Alabama at Birmingham, Birmingham, AL, ²Amgen, Detroit, MI, ³The University of Alabama at Birmingham, Birmingham, AL, ⁴Division of Rheumatology and Clinical Immunology, University of Alabama, Birmingham, AL, USA; Birmingham VA Medical Center, Birmingham, AL, USA, Birmingham, AL, ⁵Foundation for Advancing Science, Technology, Education and Research, Birmingham, AL, ⁶Amgen, Inc., Deerfield, IL
Background/Purpose: Patients with gout may be at high risk for developing osteoporosis and fractures, but osteoporosis may be under-recognized and inadequately managed for gout patients.…

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