Abstracts tagged "osteoporosis"

Abstract Number: 0544 • ACR Convergence 2020
Risk Factors for Lumbar Vertebral Osteoporosis Do Not Reflect Factors Traditionally Associated with Osteoporosis at the Hip
Marwan Bukhari¹ and Mrinalini Dey², ¹Rheumatology Department, University Hospitals of Morecambe Bay NHS Trust, Lancaster, United Kingdom, ²Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, United Kingdom
Background/Purpose: The most common site of osteoporotic fragility fractures is the thoracic spine. However, bone mineral density (BMD) measurements at the hip are used to…
Abstract Number: 1977 • ACR Convergence 2020
Delivering Fracture Prevention Through Telemedicine: A Process Evaluation
Karla Miller¹, Melissa Steffen², Aaron Seaman², Zachary Anderson¹, Janiel Green¹, Shardool Patel¹, Shylo Wardyn² and Samantha Solimeo², ¹Veterans Affairs Salt Lake City Health Care System, Salt Lake City, UT, ²Iowa VA Healthcare System, Iowa City, IA
Background/Purpose: Guidelines recommend osteoporosis screening using dual-energy X-ray absorptiometry (DXA) in men and women at risk for osteoporosis, but screening remains low, especially in men…
Abstract Number: 0102 • ACR Convergence 2020
Bone Health in Patients with Psoriatic Arthritis in the National Swiss Cohort: A Cross-sectional Study
Diana Camelia Dan¹, Youssef Ibrahimy², Berengere Aubry-Rozier³ and Daniel Aeberli⁴, ¹Lausanne University Hospital, Lausanne, Switzerland, ²University of Lausanne, Lausanne, Switzerland, ³Hôpital orthopédique, Lausanne, Switzerland, ⁴University Hospital of Bern, Bern, Switzerland
Background/Purpose: There is much controversy surrounding the loss of bone mass in patients with psoriasis arthritis (PsA). We wanted to evaluate the prevalence of osteoporosis…
Abstract Number: 0120 • ACR Convergence 2020
Risk of Fracture in Patients with Different Glucocorticoid Requiring Diseases
Giovanni Adami¹, Angelo Fassio², Alessandro Giollo², Luca Idolazzi², Ombretta Viapiana¹, Davide Gatti² and Maurizio Rossini², ¹University of Verona, Verona, Italy, ²Rheumatology Unit, University of Verona, Verona, Italy
Background/Purpose: The aim of the present work is to determine the fracture risk associated with glucocorticoids requiring diseasesMethods: We conducted a retrospective analysis of a nation-wide…
Abstract Number: 0650 • ACR Convergence 2020
Risk of Vertebral Fractures at Lateral Chest Radiographies in Patients with Gout
Marco Ferrández-Jiménez¹, Irene Calabuig², Maria Luisa Peral², Miguel Gómez-Garberí¹ and Mariano Andrés², ¹Universidad Miguel Hernández de Elche, Alicante, Spain, ²Hospital General Universitario de Alicante-ISABIAL and Universidad Miguel Hernández de Elche, Alicante, Spain
Background/Purpose: Osteoporosis causes significant morbidity and mortality through the development of fragility fractures, including vertebral fractures (VF). Patients with gout may show an increased risk…
Abstract Number: 0103 • ACR Convergence 2020
The Association of Methotrexate, Sulfasalazine and Hydroxychloroquine Use with Incident Fractures in Postmenopausal Women with Rheumatoid Arthritis: Findings from the Women’s Health Initiative
Rachel Elam¹, Sandeepkumar Gupta², Omar Tolaymat², Sowmya Vasan³, Carolyn Crandall⁴, Jean Wactawski-Wende⁵, Karen Johnson⁶ and Laura Carbone², ¹Augusta University, Evans, GA, ²Augusta University, Augusta, GA, ³WHI, Seattle, WA, ⁴UCLA, Los Angeles, CA, ⁵University of Buffalo, Buffalo, NY, ⁶University of Tennessee Health Sciences Center, Memphis, TN
Background/Purpose: This study was conducted to evaluate the extent to which disease modifying antirheumatic medications (DMARDs) used as part of triple therapy for treatment of…
Abstract Number: 0121 • ACR Convergence 2020
Association of Low Bone Density with Need for Early Revision After Elective Joint Replacement for Osteoarthritis in Postmenopausal Women
Rashmi Dhital¹, P. Daniel Nicholas², Gregory Emkey³ and Anthony Donato², ¹Reading Hospital and Medical Center, West Reading, ²Reading Hospital and Medical Center, West Reading, PA, ³Reading Hospital and Medical Center, Reading, PA
Background/Purpose: Total joint replacement (TJR) is the standard surgical treatment for end-stage hip and knee osteoarthritis (OA). Patient optimization may limit the need for early…
Abstract Number: 0926 • ACR Convergence 2020
Risk Factors for Fractures and Osteoporosis Among Patients with Systemic Sclerosis in a United States Cohort
Sina Famenini¹, Jamie Perin², Kristin Wipfler³, Kaleb Michaud⁴ and Zsuzsanna McMahan⁵, ¹Johns Hopkins School of Medicine, Baltimore, MD, ²JHUSPH, Baltimore, ³FORWARD, The National Databank for Rheumatic Diseases, Omaha, NE, ⁴University of Nebraska Medical Center, Omaha, NE, ⁵Johns Hopkins University, Baltimore
Background/Purpose:Systemic sclerosis (SSc) is associated with several risk factors for osteoporosis and fractures due to malabsorption or malnutrition, physical disability, chronic inflammation, and use of…
Abstract Number: 0104 • ACR Convergence 2020
Bone Effects of One-year Tofacitinib Treatment in Rheumatoid Arthritis
Attila Hamar¹, Anita Pusztai², Edit Végh¹, Ágnes Horváth¹, Katalin Gulyás¹, Szilvia Szamosi¹, Zsófia Pethő¹, Nóra Bodnár¹, Boglárka Soós¹, Monika Czókolyová¹, Sándor Szántó¹, Gabriella Szűcs¹, Harjit Bhattoa¹, Gábor Nagy¹, Gábor Tajti¹, Andrea Domján¹, Katalin Hodosi¹ and Zoltán Szekanecz¹, ¹University of Debrecen, Debrecen, Hungary, ²University of Debrecen Faculty of Medicine, Department of Rheumatology, Debrecen, Hungary
Background/Purpose: Oral JAK inhibitor, tofacitinib appeared as a new therapeutic option, beside biological therapies, which has already proven its safety and effectivity in RA, but…
Abstract Number: 0122 • ACR Convergence 2020
Osteoporosis Medication Utilization Patterns over Time in the ACR RISE Registry
Nitasha Khullar¹, Lang Chen², Jeffrey R Curtis³, Joshua Baker⁴, Huifeng Yun³, Andreas Reimold⁵ and Maria (Maio) Danila⁶, ¹University of Alabama Birmingham, Birmingham, AL, ²University of Alabama at Birmingham, Birmingham, AL, ³Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ⁴University of Pennsylvania, Philadelphia, PA, ⁵Veterans Affairs North Texas Healthcare System / UT Southwestern Medical Center, Dallas, TX, ⁶University of Alabama at Birmingham (UAB), Birmingham, AL
Background/Purpose: Many effective medications are available for osteoporosis treatment. However how rheumatologists use these therapies is not well understood, particularly in patients with concomitant rheumatologic…
Abstract Number: 0966 • ACR Convergence 2020
Decoupling Inflammation and Bone Loss in Rheumatoid Arthritis via Schnurri-3
Zheni Stavre¹, JungMin Kim², Jae-Hyuck Shim² and Ellen Gravallese³, ¹University of Massachusetts Medical School-Rheumatology Division, Worcester, MA, ²University of Massachusetts Medical School, Worcester, MA, ³Brigham and Women's Hospital, Boston, MA
Background/Purpose: Rheumatoid arthritis (RA) is a chronic inflammatory disease that leads to local and systemic bone loss. TNF is a key mediator of bone loss,…
Abstract Number: 0105 • ACR Convergence 2020
Use of Peripheral Quantitative Computed Tomography in the Assessment of Bone Mineral Density in Anti-TNF-treated Rheumatoid Arthritis and Ankylosing Spondylitis Patients
Balázs Juhász¹, Katalin Gulyás¹, Ágnes Horváth¹, Edit Végh¹, Anita Pusztai², Ágnes Szentpétery³, Zsófia Pethő¹, Nóra Bodnár¹, Attila Hamar¹, Levente Bodoki¹, Harjit Bhattoa¹, Éva Szekanecz¹, Katalin Hodosi¹, Andrea Domján¹, Szilvia Szamosi¹, Csaba Horváth⁴, Sándor Szántó¹, Gabriella Szűcs¹, Hennie Raterman⁵, Oliver FitzGerald⁶ and Zoltán Szekanecz¹, ¹University of Debrecen, Debrecen, Hungary, ²University of Debrecen Faculty of Medicine, Department of Rheumatology, Debrecen, Hungary, ³Uppsala University Hospital, Uppsala, Sweden, ⁴Semmelweis University, Budapest, Hungary, ⁵Northwest Clinics, Alkmaar, Netherlands, ⁶Conway Institute for Biomolecular Research, University College Dublin, Dublin, Ireland
Background/Purpose: Rheumatoid arthritis (RA) and ankylosing spondylitis (AS) have both been associated with generalized and localized bone loss. Inflammatory cytokines like tumor necrosis factor (TNF)…
Abstract Number: 0123 • ACR Convergence 2020
Aromatase Inhibitor-Associated Bone Loss: Screening and Prevention
Matthew White¹ and Luke Barre², ¹Roger Williams Medical Center, Providence, RI, ²Hawthorn Medical Associates, Dartmouth, MA
Background/Purpose: Aromatase inhibitors (AI) are frequently used in hormone receptor-positive breast cancer, which encompasses nearly 75% of all breast cancers. By preventing peripheral estrogen production,…
Abstract Number: 1206 • ACR Convergence 2020
Associations of Vascular and Bone Status in Anti-TNF-treated Rheumatoid Arthritis and Ankylosing Spondylitis Patients
Anita Pusztai¹, Attila Hamar², Monika Czókolyová², Katalin Gulyás², Ágnes Horváth², Edit Végh², Zsófia Pethő², Szilvia Szamosi², Emese Balogh², Nóra Bodnár², Ágnes Szentpétery³, Harjit Bhattoa², György Kerekes², Balázs Juhász², Éva Szekanecz², Katalin Hodosi², Andrea Domján², Sándor Szántó², Hennie Raterman⁴, Willem Lems⁵, Zoltán Szekanecz² and Gabriella Szűcs², ¹University of Debrecen Faculty of Medicine, Department of Rheumatology, Debrecen, Hungary, ²University of Debrecen, Debrecen, Hungary, ³Uppsala University Hospital, Uppsala, Sweden, ⁴Northwest Clinics, Alkmaar, Netherlands, ⁵Amsterdam Rheumatology and Immunology Centre, Amsterdam, Netherlands
Background/Purpose: Cardiovascular (CV) disease and osteoporosis (OP) have become increasing challenges in the ageing population, even more in patients with inflammatory rheumatic diseases, such as…
Abstract Number: 0106 • ACR Convergence 2020
A Machine Learning-derived Radiomics Nomogram for Diagnosis of Osteoporosis and Osteopenia
Qianrong Xie¹, Yue Chen², Yimei Hu³, Fanwei Zeng⁴, Pingxi Wang⁴, Lin Xu⁵, Jianhong Wu⁶, Jie Li¹, Jing Zhu⁷, Ming Xiang⁸ and Fanxin Zeng⁹, ¹Department of Clinical Research Center, Dazhou Central Hospital, Dazhou, China (People's Republic), ²Department of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, China (People's Republic), ³Department of Orthopedics, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China (People's Republic), ⁴Department of bone disease, Dazhou Central Hospital, Dazhou, China (People's Republic), ⁵Department of medical imaging, Dazhou Central Hospital, Dazhou, China (People's Republic), ⁶Department of Rheumatology, Dazhou Central Hospital, Dazhou, China (People's Republic), ⁷Department of Rheumatology and Immunology, Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, Chengdu, China (People's Republic), ⁸Department of Orthopedics, Sichuan Provincial Orthopedic Hospital, Chengdu, China (People's Republic), ⁹Department of Clinical Research Center, Dazhou Central Hospital, Dazhou, Sichuan, China (People's Republic)
Background/Purpose: To discriminate osteoporosis and osteopenia using a quantitative computed tomography (QCT) radiomics signatures and clinical variables.Methods: This retrospective study enrolled 635 patients with QCT images and clinical characteristics from November…

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