Abstracts tagged "osteoporosis"

Abstract Number: 2220 • 2019 ACR/ARP Annual Meeting
Abaloparatide Followed by Alendronate on Bone Mineral Density and Fracture Incidence in Postmenopausal Women with Osteoporosis and Osteoarthritis
Nancy Lane¹, Richard Weiss ², Bruce Mitlak ³, Yamei Wang ⁴, Guillermo Valenzuela ⁵ and Chad Deal ⁶, ¹University of California at Davis Medical Center, Sacramento, CA, ²Radius Health, Inc, Waltham, ³Radius Health, Inc, Waltham, MA, ⁴Radius Health, Inc, Waltham, ⁵Integral Rheumatology & Immunology Specialists, Plantation, FL, ⁶Cleveland Clinic Foundation, Cleveland, OH
Background/Purpose: Osteoporosis (OP) and osteoarthritis (OA) are often comorbid conditions in the elderly, with prevalence of OP in patients with OA reported as high as…
Abstract Number: 1929 • 2019 ACR/ARP Annual Meeting
Identification and Validation of Transcriptional Genes Associated with Osteoporotic Vertebral Fractures by Microarray Study, in Community Elderly Women
Levi Jales Neto¹, Zofia Wicik ², Georgea Torres ¹, Liliam Takayama ¹, Neusa Lopes ¹, alexandre Pereira ¹ and Rosa Pereira ³, ¹University of Sao Paulo, Sao Paulo, Brazil, ²University of Sao Paulo, São Paulo, Brazil, ³Faculdade de Medicina da Universidade de Sao Paulo, São Paulo, Sao Paulo, Brazil
Background/Purpose: The pathogenesis of osteoporosis, a common disease with high morbidity1, comprises genetic and environmental factors2. Recent studies demonstrated that blood samples are a source…
Abstract Number: 2221 • 2019 ACR/ARP Annual Meeting
Bone Metabolism Impairment in Heart Transplant: Results from a Prospective Cohort Study
Luis Seguro ¹, Rosa Pereira ², Luciana Seguro³, Valeria Caparbo ³, Monica Avila ¹, Sandrigo Mangini ¹, Iascara Campos ¹, Fabio Gaiotto ¹, Fabiana Marcondes-Braga ¹ and Fernando Bacal ¹, ¹Instituto do Coracao (InCor), HCFMUSP, Sao Paulo, ²Faculdade de Medicina da Universidade de Sao Paulo, São Paulo, Sao Paulo, Brazil, ³Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo
Background/Purpose: Data on prevention of fractures after heart transplant (HTx) are controversial in the literature. Understanding the effects of HTx on bone may guide appropriate…
Abstract Number: 1971 • 2019 ACR/ARP Annual Meeting
CD39 Produced from Human Gingiva-Derived Mesenchymal Stem Cells Regulates the Balance of Osteoclasts and Osteoblasts Through Wnt / β-catenin Pathway in Osteoporosis
Wenbin Wu¹, Julie Wang ², feng huang ¹, limin Rong ¹ and Song Guo Zheng ³, ¹Sun Yat-sen University, Guangzhou, ²Ohio State University, columbus, ³Ohio State College of Medicine, Columbus, OH
Background/Purpose: Osteoporosis led to severe bone-related diseases and increased mortality and health care costs. Existing treatments failed to reduce the risk of fractures in patients,…
Abstract Number: 2222 • 2019 ACR/ARP Annual Meeting
Bone Health: An Independent Predictor of Coronary Artery Disease
Lilian Bizzocchi¹, Maria Salgado ¹, Bhavin Chokshi ¹, Navneet Kaur ¹, Oscar Mena ¹ and Michal Packman ², ¹Jacobi Medical Center, Bronx, NY, ²North Central Bronx Hospital, Bronx, NY
Background/Purpose: An association between low bone mineral density (BMD) and cardiovascular events has been shown. The calcification process observed in atherosclerosis and bone mineralization have…
Abstract Number: 2102 • 2019 ACR/ARP Annual Meeting
First-line Antiretroviral Therapy with Tenofovir Produces Deleterious Effects on Bone and an Increase in Proinflammatory Cytokines Expression After 12 Months of Treatment in Naïve HIV Patients
Francisco Conesa-Buendia¹, Patricia Atencio ¹, Alfonso Cabello ², Patricia Llamas-Granda ³, Ignacio Mahillo-Fernández ⁴, Raquel Largo ⁵, Gabriel Herrero-Beaumont ⁵, Miguel Gorgolas ¹ and Aranzazu Mediero ¹, ¹IIS-FUNDACION JIMENEZ DIAZ, Madrid, Spain, ²IIS FUNDACION JIMENEZ DIAZ, Madrid, Spain, ³IIS-FUNDACION JIMENEX DIAZ, Madrid, Spain, ⁴IIS- FUNDACION JIMENEZ DIAZ, Madrid, Spain, ⁵IIS-Fundación Jiménez Díaz, Madrid, Madrid, Spain
Background/Purpose: For almost two decades, bone alterations have been observed in the course of HIV infection, characterized by a marked decrease in bone mineral density…
Abstract Number: 2224 • 2019 ACR/ARP Annual Meeting
Parkinson’s Disease and Risk of Fractures : A Meta Analysis of Cohort Studies
marion louvois¹, stéphanie Ferrero ¹, Thomas Barnetche ², christian roux ¹ and Véronique Breuil ¹, ¹university of nice, nice, France, ²university of bordeaux, bordeaux, France
Background/Purpose: Parkinson's disease is a common neurodegenerative disorder in older adults. Parkinson's patients have an increase risk of falls. More over, previous studies have shown…
Abstract Number: 2204 • 2019 ACR/ARP Annual Meeting
Fragility Fractures in a Community Setting: Clinical Characteristics, Care Gaps, and Outcomes
Rachel Kneeland¹, Keile Wahle ¹, Ishwar Gill ¹, Yangyang Liu ² and Monika Starosta ³, ¹Department of Internal Medicine, Advocate Lutheran General Hospital, Park Ridge, IL, ²Russell Center for Research & Innovation, Advocate Lutheran General Hospital, Park Ridge, IL, ³Department of Rheumatology, Advocate Lutheran General Hospital, Park Ridge, IL
Background/Purpose: Osteoporosis-related fragility fractures contribute to significant morbidity and mortality. The risk of subsequent hip fracture is significantly increased after initial fracture, with some reports…
Abstract Number: 2225 • 2019 ACR/ARP Annual Meeting
Systematic Osteoporosis Screening in Chronic Obtructive Pulmonary Disease (Study of Correlation Between Pulmonary Functions Tests and Bone Parameters): Emphysematous Status Is Linked to Low Bone Density and Osteoporosis
Olivier Malaise¹, Cécile André ¹, Laurence Seidel ², Florence Schleich ³, Renaud Louis ³ and Michel Malaise ¹, ¹Rheumatology department, CHU and University of Liège, Liège, Belgium, ²Biostatistics department, CHU and University of Liège, Liège, Belgium, ³Pneumology department, CHU and University of Liège, Liège, Belgium
Background/Purpose: Chronic obstructive pulmonary disease (COPD) is usually considered as a risk factor for osteoporosis. However, COPD is an heterogeneous disease with different phenotypes, based…
Abstract Number: 151 • 2019 ACR/ARP Annual Meeting
Implementation of Recommendations for Prevention of Glucocorticosteroid-Induced Osteoporosis in Hospitalized Patients
Tal Gazitt¹, Muna Elias ¹, Joy Feld ¹, Idit Lavi ¹, Amir Haddad ¹, Rema Bishara-Garzuzi ¹, Muhanad Abu Elhija ¹, Adi Kibari ¹ and Devy Zisman ², ¹Carmel Hospital, Haifa, Israel, ²Carmel Hospital and Ruth and Bruce Rappaport Faculty of Medicine, Technion, Israel, Haifa, Israel
Background/Purpose: Glucocorticosteroid-induced osteoporosis (GIO) is the most common cause of secondary osteoporosis but is under-diagnosed and under-treated. Most professional guidelines recommend as a first step…
Abstract Number: 2206 • 2019 ACR/ARP Annual Meeting
MRI-based Textural Analysis of Trabecular Bone: A Novel Method for the Opportunistic Screening of Bone Quality
Jonathan Cheah¹, Matthew Koff ¹, Ryan Breighner ¹, Bin Lin ¹, Conor Jones ², Janice Havasy ², Mikas Grewal ¹ and Emily Stein ¹, ¹Hospital for Special Surgery, New York, NY, ²Weill Cornell Medicine, New York, NY
Background/Purpose: A major obstacle to the treatment of osteoporosis and prevention of fractures is that many at-risk patients are never screened. Dual energy x-ray absorptiometry…
Abstract Number: 2226 • 2019 ACR/ARP Annual Meeting
Factors Contributing to Fracture in Pernicious Anemia Patients Presenting with Symptomatic Subacute Vertebral Compression Fractures
Michael Lovy¹, Nir Ben-Shlomo ² and Jacob Hattenbach ³, ¹Desert Oasis Healthcare, Palm Springs, CA, ²Ben-Gurion Medical School, Beer Sheva, Israel, ³College of Osteopathic Medicine of the Pacific, Pomona
Background/Purpose: Pernicious anemia (PA) has been associated with both low spine BMD and increased fracture risk in retrospective cohort studies. The cause of these observations…
Abstract Number: 1144 • 2018 ACR/ARHP Annual Meeting
Risk of Osteoporotic Fractures in Patients with Rheumatoid Arthritis and End Stage Renal Disease. Findings from the Usrds Database
Renee Peterkin-McCalman, Jennifer Waller, Brian Le, Alyce Oliver, Evan Manning, Stanley Nahman and Laura Carbone, Medical College of Georgia at Augusta University, Augusta, GA
Background/Purpose: Rheumatoid arthritis (RA) and End Stage Renal Disease (ESRD) are independent risk factors for osteoporotic fractures. Approximately one percent of persons with ESRD have…
Abstract Number: 1633 • 2018 ACR/ARHP Annual Meeting
Fragility Fractures in Psoriatic Arthritis Patients: A Matched-Control Study
Luciano Fernando Lo Giudice¹, Marina Scolnik², Florencia Pierini³, Nicolas Martin Marin Zucaro¹, John Fredy Jaramillo Gallego¹ and Enrique R Soriano², ¹Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Capital Federal, Argentina, ²Rheumatology Unit, Internal Medicine Service. Hospital Italiano Buenos Aires. Argentina, Buenos Aires, Argentina, ³Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, CABA, Argentina
Background/Purpose: patients with Psoriatic Arthritis (PsA) in spite of having bone production as one of their characteristic features, very often have osteoporosis, but scarce data…
Abstract Number: 2182 • 2018 ACR/ARHP Annual Meeting
Defining Alendronate Drug Holidays and Re-Initiation in US Medicare Data
Ayesha Jaleel¹, Jeffrey R. Curtis², Rui Chen², Huifeng Yun³, Phillip J. Foster⁴, Nicole Wright³, Tarun Arora², Amy S. Mudano², Suzanne Cadarette⁵ and Kenneth Saag², ¹Internal Medicine, Baptist Brookwood Health, Birmingham, AL, ²University of Alabama at Birmingham, Birmingham, AL, ³Epidemiology, University of Alabama at Birmingham, Birmingham, AL, ⁴Department of Medicine, Division of Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ⁵Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada
Background/Purpose: Given alendronate’s (ALN) prolonged skeletal retention and emerging safety concerns, the ASBMR task force recommended consideration of a “drug holiday” after 5 years of…

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