ACR Meeting Abstracts

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Abstracts tagged "osteoporosis"

  • Abstract Number: 1333 • 2019 ACR/ARP Annual Meeting

    The Comparative Risk of Osteoporotic Fractures Among Patients with Rheumatoid Arthritis Receiving TNF Inhibitors versus Other Biologics: A Nation-wide Cohort Study in Korea

    Eun Hye Park1, Anna Shin 2, Yaa-Hui Dong 3, You-Jung Ha 1, Yun Jong Lee 4, Eun Bong Lee 5, Yeong-Wook Song 6 and Eun Ha Kang 1, 1Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea, Seongnam, Republic of Korea, 2Seoul National University Bundang Hospital, Seongnam, Republic of Korea, 3Graduate Institute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei, Taiwan (Republic of China), 4Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea, Seongnam, Republic of Korea, 5Division of Rheumatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea, seoul, 6Seoul National University Hospital, Seoul, Republic of Korea

    Background/Purpose: Rheumatoid arthritis (RA) is associated with an increased risk of osteoporosis and osteoporotic fracture, but little is known about comparative risk of osteoporotic fractures between…
  • Abstract Number: 2215 • 2019 ACR/ARP Annual Meeting

    Modeling-Based Bone Formation Persists in the Femoral Neck Despite Remodeling Inhibition in Subjects Treated with Denosumab

    David Dempster1, Peter Butler 2, Mathias Bostrom 3, Jeri Nieves 1, Hua Zhou 4, Li Chen 2, Nicola Pannacciulli 2, Rachel Wagman 2 and Felicia Cosman 1, 1Columbia University, New York, NY, 2Amgen Inc., Thousand Oaks, CA, 3Hospital for Special Surgery, New York, NY, 4Helen Hayes Hospital, West Haverstraw, NY

    Background/Purpose: Denosumab (DMAb) is a potent antiresorptive agent, but findings in non-human primates suggest that modeling-based bone formation (MBBF) may persist despite DMAb treatment (Ominsky…
  • Abstract Number: 1872 • 2019 ACR/ARP Annual Meeting

    Worsening Trends in Osteoporosis Management in the Medicare Population: 2010-2014

    Jeffrey Curtis1, Shanette G. Daigle 2, Setareh A. Williams 3, Richard Weiss 3, Yamei Wang 4 and Tarun Arora 2, 1University of Alabama at Birmingham, Birmingham, AL, 2University of Alabama at Birmingham, Birmingham, 3Radius Health, Inc, Waltham, 4Radius Health, Inc, Waltham

    Background/Purpose: Osteoporotic fractures are an important public health burden, and with an increasing aging population, the number of Americans at risk of fractures is projected…
  • Abstract Number: 2216 • 2019 ACR/ARP Annual Meeting

    Bone Mineral Density of the Spine, Hip, and Distal Radius in Patients with Postmenopausal Osteoporosis

    KEN NAKASEKO1, 1Department of Orthopaedic Surgery and Rheumatology Kuwana City Medical Center, kuwana mie, Japan

    Background/Purpose: Bone mineral density (BMD) is used for the diagnosis of osteoporosis, predicting future fracture risk, and monitoring osteoporosis treatment. Osteoporosis is defined as BMD…
  • Abstract Number: 1873 • 2019 ACR/ARP Annual Meeting

    Geisinger HiROC Performance 2017-2018: Continuing to Narrow the Post-Fracture Treatment Gap

    Thomas Olenginski1 and Karen Mackiewicz 2, 1Geisinger Medical Center, Danville, PA, 2Geisinger, Danville, PA

    Background/Purpose: The morbidity and mortality of osteoporotic fractures threaten our aging population. Despite advances in new therapies for osteoporosis and technology to more effectively communicate, fewer…
  • Abstract Number: 2217 • 2019 ACR/ARP Annual Meeting

    DEXA Does Not Accurately Reflect FRAX Score in Patients with Autoimmune Disease on Corticosteroids

    Sima Terebelo1, Madina Abduraimova 1, Latoya Freeman-Beman 1, Naureen Kabani 2, Joshy Pathiparampil 1, Olga Dvorkina 2 and Ellen M Ginzler 3, 1SUNY Downstate Medical Center, Brooklyn, NY, 2SUNY Downstate Medical Center, Brooklyn, 3State University of New York Downstate Medical Center, Brooklyn, NY

    Background/Purpose: Osteoporosis (OP) is a problem in the aging population.  Patients with autoimmune disease are at increased risk for OP given their history of steroid…
  • Abstract Number: 1874 • 2019 ACR/ARP Annual Meeting

    Extensive Modeling-Based Bone Formation After 2 Months of Romosozumab Treatment: Results from the FRAME Clinical Trial

    Erik Eriksen1, Roland Chapurlat 2, Rogely Boyce 3, Jacques Brown 4, Stéphane Horlait 5, Cesar Libanati 6, Yifei Shi 3, Rachel Wagman 3 and Pascale Chavassieux 2, 1Department of Clinical Endocrinology, Oslo University Hospital and Institute of Clinical Medicine Oslo University, Oslo, Norway, 2INSERM UMR 1033, Université de Lyon, Lyon, France, 3Amgen Inc., Thousand Oaks, CA, 4CHU de Quebec Research Centre and Laval University, Quebec, QC, Canada, 5Amgen Inc., Boulogne Billancourt, France, 6UCB Pharma, Brussels, Belgium

    Background/Purpose: The bone-forming agent romosozumab (Romo) is a monoclonal antibody that binds to/inhibits sclerostin, leading to increased bone formation and decreased bone resorption. The highest…
  • Abstract Number: 2219 • 2019 ACR/ARP Annual Meeting

    Randomized Control Study in Glucocorticoid-Induced Osteoporosis Treated with Bisphosphonate or Denosumab (GOBID)

    Ikuko Tanaka1, Mari Ushikubo 2, Misako Konishi 2, Yutaro Hayashi 2, Satoshi Hama 3, Keisuke Izumi 2, Yutaka Okano 2, Shigenori Tamaki 4 and Hisaji Ohshima 2, 1Nagoya Rheumatology Clinic, Ngoya, Japan, 2National Tokyo Medical Center, Tokyo, Japan, 3tokyo medical center, tokyo, Japan, 4Nagoya Rheumatology Clinic, Nagoya, Japan

    Background/Purpose: It has not been established which therapy, bisphosphonates or denosumab, is more effective for glucocorticoid-induced osteoporosis (GIO). The purpose of this study was to…
  • Abstract Number: 1877 • 2019 ACR/ARP Annual Meeting

    Romosozumab Improves Lumbar Spine Bone Mineral Density and Bone Strength Greater Than Alendronate as Assessed by Quantitative Computed Tomography and Finite Element Analysis in the ARCH Trial

    Jacques Brown1, Arkadi Chines 2, Roland Chapurlat 3, Joseph Foldes 4, Xavier Nogues 5, Roberto Civitelli 6, Tobias De Villiers 7, Fabio Massari 8, Cristiano A. Zerbini 9, Wenjing Yang 2, Chris Recknor 10 and Cesar Libanati 11, 1CHU de Quebec Research Centre and Laval University, Quebec, QC, Canada, 2Amgen Inc., Thousand Oaks, CA, 3INSERM UMR 1033, Université de Lyon, Lyon, France, 4Hadassah Hebrew University Medical Center, Jerusalem, Israel, 5IMIM Institut Hospital del Mar d’Investigacions Mèdiques, Barcelona, Spain, 6Washington University School of Medicine, St. Louis, MO, 7Stellenbosch University, Stellenbosch, South Africa, 8Instituto de Investigaciones Metabólicas, Buenos Aires, Argentina, 9Centro Paulista de Investigação Clinica, São Paulo, Brazil, 10United Osteoporosis Centers, Gainesville, GA, 11UCB Pharma, Brussels, Belgium

    Background/Purpose: Recent evidence suggests BMD achieved during treatment is a reliable surrogate for fracture risk reduction (Bouxsein JBMR 2019). Romosozumab (Romo) is a bone-forming agent…
  • Abstract Number: 2220 • 2019 ACR/ARP Annual Meeting

    Abaloparatide Followed by Alendronate on Bone Mineral Density and Fracture Incidence in Postmenopausal Women with Osteoporosis and Osteoarthritis

    Nancy Lane1, Richard Weiss 2, Bruce Mitlak 3, Yamei Wang 4, Guillermo Valenzuela 5 and Chad Deal 6, 1University of California at Davis Medical Center, Sacramento, CA, 2Radius Health, Inc, Waltham, 3Radius Health, Inc, Waltham, MA, 4Radius Health, Inc, Waltham, 5Integral Rheumatology & Immunology Specialists, Plantation, FL, 6Cleveland Clinic Foundation, Cleveland, OH

    Background/Purpose: Osteoporosis (OP) and osteoarthritis (OA) are often comorbid conditions in the elderly, with prevalence of OP in patients with OA reported as high as…
  • Abstract Number: 1929 • 2019 ACR/ARP Annual Meeting

    Identification and Validation of Transcriptional Genes Associated with Osteoporotic Vertebral Fractures by Microarray Study, in Community Elderly Women

    Levi Jales Neto1, Zofia Wicik 2, Georgea Torres 1, Liliam Takayama 1, Neusa Lopes 1, alexandre Pereira 1 and Rosa Pereira 3, 1University of Sao Paulo, Sao Paulo, Brazil, 2University of Sao Paulo, São Paulo, Brazil, 3Faculdade de Medicina da Universidade de Sao Paulo, São Paulo, Sao Paulo, Brazil

    Background/Purpose: The pathogenesis of osteoporosis, a common disease with high morbidity1, comprises genetic and environmental factors2. Recent studies demonstrated that blood samples are a source…
  • Abstract Number: 2221 • 2019 ACR/ARP Annual Meeting

    Bone Metabolism Impairment in Heart Transplant: Results from a Prospective Cohort Study

    Luis Seguro 1, Rosa Pereira 2, Luciana Seguro3, Valeria Caparbo 3, Monica Avila 1, Sandrigo Mangini 1, Iascara Campos 1, Fabio Gaiotto 1, Fabiana Marcondes-Braga 1 and Fernando Bacal 1, 1Instituto do Coracao (InCor), HCFMUSP, Sao Paulo, 2Faculdade de Medicina da Universidade de Sao Paulo, São Paulo, Sao Paulo, Brazil, 3Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo

    Background/Purpose: Data on prevention of fractures after heart transplant (HTx) are controversial in the literature. Understanding the effects of HTx on bone may guide appropriate…
  • Abstract Number: 2323 • 2018 ACR/ARHP Annual Meeting

    Predictors of Mortality in Patients with Hip Fragility Fracture

    Miguel Guerra1, Sara Ganhão2,3, Francisca Aguiar2,3, Georgina Terroso2, Romana Vieira1, Diana Gonçalves4, Tiago Meirinhos5, Teresa Martins-Rocha2,3, Ana Águeda3,5, Raquel Ferreira2,3, Miguel Bernardes2,3, Carlos Vaz2,3, Raquel Lucas6 and Lúcia Costa2, 1Rheumatology, Centro Hospitalar de Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal, 2Rheumatology, Centro Hospitalar de São João, Oporto, Portugal, 3Faculty of Medicine, Oporto University, Oporto, Portugal, 4Rheumatology, Centro Hospitalar de Trás-os-Montes e Alto Douro, Vila Real, Portugal, 5Rheumatology, Centro Hospitalar do Baixo Vouga, Aveiro, Portugal, 6Public Health Institute of Oporto University, Oporto, Portugal

    Background/Purpose: In Osteoporosis, hip fractures account for significant disease burden, with increased morbi-mortality and financial load on the patient and healthcare system. This study aimed…
  • Abstract Number: 2326 • 2018 ACR/ARHP Annual Meeting

    Outcomes One Year after Hip Fracture Repair in the Elderly: Does Social Isolation Matter?

    Lisa A. Mandl1, Serena Lian1, Jackie Szymonifka2, Kirsten Grueter3, Aidan Hadad3 and Joseph Lane3, 1Rheumatology, Hospital for Special Surgery, New York, NY, 2Hospital for Special Surgery, New York, NY, 3Orthopaedic Surgery, Hospital for Special Surgery, New York, NY

    Background/Purpose: Hip fractures are a serious public health issue with a significant population burden, especially among those over age 65. Social isolation—how integrated a patient…
  • Abstract Number: 2336 • 2018 ACR/ARHP Annual Meeting

    Identification of Osteoporosis As a Reason for Vertebral Fractures in Patients with Rheumatoid Arthritis and Non-Inflammatory Musculoskeletal Diseases – a Comparison between Trabecular Bone Score (TBS) and Bone Mineral Density (BMD)

    Bjoern Buehring1, Xenofon Baraliakos1, Julian Thomas2 and Jürgen Braun1, 1Ruhr-University Bochum, Herne, Germany, 2Rheumazentrum Ruhrgebiet, Herne, Germany

    Identification of osteoporosis as a reason for vertebral fractures in patients with rheumatoid arthritis and non-inflammatory musculoskeletal diseases – A comparison between trabecular bone score…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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