Abstracts tagged "osteoporosis"

Abstract Number: 0133 • ACR Convergence 2020
Pharmacist-Driven Clinic Development for Patients with Incidental Vertebral or Hip Fractures
Julie Ferm¹, Lanh Dang¹ and Gurjit Kaeley², ¹UF Health Jacksonville, Jacksonville, FL, ²University of Florida College of Medicine - Jacksonville, Jacksonville, FL
Background/Purpose: Non-traumatic vertebral and hip fractures are detrimental complications of osteoporosis and those with a previous fracture have double the risk of subsequent fractures. The…
Abstract Number: 1973 • ACR Convergence 2020
Treatment Sequences with Romosozumab Before or After Antiresorptive Medication
Felicia Cosman¹, David Kendler², Bente Langdahl³, Benjamin Z Leder⁴, E Michael Lewiecki⁵, Akimitsu Miyauchi⁶, Maria Rojeski⁷, Michele McDermott⁷, Mary Oates⁷, Cassandra E Milmont⁸, Cesar Libanati⁹ and Serge Ferrari¹⁰, ¹Columbia University, New York, NY, ²University of British Columbia, Vancouver, BC, Canada, ³Aarhus University Hospital, Aarhus, Denmark, ⁴Mass General Hospital, Harvard Medical School, Boston, MA, Boston, MA, ⁵New Mexico Clinical Research & Osteoporosis Center, Albuquerque, NM, ⁶Miyauchi Medical Center, Osaka, Japan, ⁷Amgen Inc., Thousand Oaks, CA, ⁸Amgen Inc., Thousand Oaks, ⁹UCB Pharma, Brussels, Belgium, ¹⁰Geneva University Hospital, Geneva, Switzerland
Background/Purpose: Prior studies of anabolic/antiresorptive treatment sequences indicate that using teriparatide first followed by an antiresorptive results in greater bone mineral density (BMD) gains, particularly…
Abstract Number: 0115 • ACR Convergence 2020
Improving Osteoporosis Screening in Men at a Resident-run Primary Care Clinic: A Quality Improvement Project
Khiem Vu¹, Chima Ohadugha¹, Kevin Dao¹, Rabih Nayfe² and Andrew Mangano¹, ¹Grand Strand Medical Center, Myrtle Beach, SC, ²Carolina Health Specialists - Rheumatology, Myrtle Beach, SC
Background/Purpose: There are known indications for osteoporosis screening in women. However, osteoporosis also occurs in men and fragility fractures are linked to increased morbidity and…
Abstract Number: 0188 • ACR Convergence 2020
The Risk of Fractures in a Community-based Cohort of Patients with Rheumatoid Arthritis Compared with the Background Population
Lisa Theander¹, Jan Åke Nilsson², Minna Willim³, Lennart T.H. Jacobsson⁴ and Carl Turesson⁵, ¹Rheumatology, Department of Clinical Sciences, Malmö, Lund University, Sweden, Malmö, Sweden, ²Rheumatology, Department of Clinical Sciences, Malmö, Lund University. Department of Rheumatology, Skåne University Hospital, Malmö and Lund, Sweden, Malmö, Sweden, ³Rheumatology, Department of Clinical Sciences, Lund, Lund University. Department of Rheumatology, Skåne University Hospital, Malmö and Lund, Sweden, Malmö, Sweden, ⁴Rheumatology, Department of Clinical Sciences, Malmö, Lund University. Department of Rheumatology and inflammation research, Institute of Medicine, Sahlgrenska University Hospital, University of Gothenburg, Gothenburg, Sweden., Gothenburg, Sweden, ⁵Rheumatology, Department of Clinical Sciences Malmö, Lund University, Department of Rheumatology, Skåne University Hospital, Malmö, Sweden., Malmö, Sweden
Background/Purpose: Rheumatoid Arthritis (RA) has been associated with increased risk of osteoporosis and fractures. We have recently presented results on DXA measurements over 10 years…
Abstract Number: 1974 • ACR Convergence 2020
Validation of a Deep Learning Based Algorithm to Diagnose Vertebral Compression Fractures
John Page¹, Franklin Moser², Marcel Maya³, Ravi Prasad³ and Barry Pressman², ¹Amgen, Inc, Thousand Oaks, CA, ²Cedars-Sinai Medical Center, Los Angeles, CA, ³Cedars-Sinai Medical Center, Los Angeles
Background/Purpose: Vertebral Compression Fractures are common in patients above age 50, but are often undiagnosed. Patients with one VCF are at higher risk of other…
Abstract Number: 0117 • ACR Convergence 2020
Development of an In Vitro Trabecular Human Bone Model to Recapitulate Features of Glucocorticoid-induced Osteoporosis
Annemarie Lang¹, Karoline Diesing¹, Alexandra Damerau¹, Moritz Pfeiffenberger¹, Timo Gaber¹ and Frank Buttgereit², ¹Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Rheumatology and Clinical Immunology, Berlin, Germany, ²Charité University Medicine, Berlin, Germany
Background/Purpose: The bone matrix consists of inorganic and organic components and a variety of specialized cells such as osteoblasts, osteocytes and osteoclasts. The bone-forming osteoblasts…
Abstract Number: 0394 • ACR Convergence 2020
Prevalence of a Diagnosis of Osteopenia/Osteoporosis Amongst Patients with Systemic Sclerosis and Identification of Associated Clinical Factors
Guanying Wang¹, Diane Mar², Joy Wu³, Julia Simard⁴, Rita Popat¹ and Lorinda Chung⁵, ¹Department of Epidemiology & Population Health, Stanford University School of Medicine, Palo Alto, CA, ²Stanford Department of Immunology/Rheumatology, Palo Alto, CA, ³Department of Medicine, Division of Endocrinology, Stanford University School of Medicine, Palo Alto, CA, ⁴Stanford Medicine, Stanford, CA, ⁵Stanford University School of Medicine and Palo Alto VA Health Care System, Palo Alto, CA
Background/Purpose: This study aims to determine the prevalence of a diagnosis of osteopenia/osteoporosis (OP) in systemic sclerosis (SSc) patients and to identify the clinical and…
Abstract Number: 1975 • ACR Convergence 2020
Predicting Bone Mineral Density of Lumbar Vertebrae by Assessing Plain Film with Deep Learning
Chen-I Hsieh¹, Chang-Fu Kuo¹, Shun Miao², Kang Zheng² and Le Lu², ¹Chang Gung Memorial Hospital, Taoyuan, Taiwan (Republic of China), ²PAII labs, Bethesda, MD
Background/Purpose: Osteoporosis is a silent disease characterized by a decrease in bone mineral density (BMD), causing bone fragility and increased risk of fracture. The most…
Abstract Number: 0090 • ACR Convergence 2020
110 Patients with Monoclonal Gammopathy of Undetermined Significance (MGUS) in a Rheumatology Disease Unit: Fracture, Neuropathy, and Pernicious Anemia Are Clues to Recognition
Michael Lovy¹ and Andrew Dulalia¹, ¹Desert Oasis Healthcare, Palm Springs, CA
Background/Purpose: Monoclonal gammopathy of undetermined significance (MGUS) has been associated with osteoporosis, neuropathy, pernicious anemia, and low vitamin B12, and may precede multiple myeloma and…
Abstract Number: 0118 • ACR Convergence 2020
Indicators of Effectiveness After 6 Years of Follow-up in a Fracture Liaison Service
Antonio Naranjo Hernandez¹, Amparo Molina², Cristina Sepúlveda², Francisco Rubiño³, Adrian Quevedo³ and Soledad Ojeda³, ¹Hospital Universitario Dr Negrin, Las Palmas, Canarias, Spain, ²Hospital Universitario de Gran Canaria Dr Negrin, Las Palmas, Spain, ³Hospital Universitario de Gran Canaria Dr Negrin, Las Palmas
Background/Purpose: Data on the effectiveness of FLS in the medium and long term are needed. The objetive of this study was to analyze the indicators of…
Abstract Number: 0533 • ACR Convergence 2020
Characterization of Older Male Patients with a Fragility Fracture
Setareh A Williams¹, Shanette G Daigle², Richard Weiss¹, Yamei Wang¹, Tarun Arora² and Jeffrey R Curtis³, ¹Radius Health, Inc., Waltham, MA, Waltham, MA, ²University of Alabama at Birmingham, Birmingham, AL, Birmingham, AL, ³Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Osteoporosis is associated with significant burden in terms of adverse patient outcomes, mortality, and cost; and is particularly common in the older Medicare population.…
Abstract Number: 1976 • ACR Convergence 2020
High Disease Activity Is Associated with Incident Osteoporotic Fractures Among Veterans with Rheumatoid Arthritis
Katherine Wysham¹, Ted Mikuls², Bryant England², Dolores Shoback³, Patricia Katz⁴, Jose Garcia¹, Brian Sauer⁵, Beth Wallace⁶, John Richards⁷, Paul Monach⁸, Grant Cannon⁹ and Joshua Baker¹⁰, ¹VA Puget Sound/University of Washington, Seattle, WA, ²University of Nebraska Medical Center, Omaha, NE, ³San Francisco VA/University of California, San Francisco, San Francisco, CA, ⁴University of California, San Francisco, Novato, CA, ⁵University of Utah, Omaha, NE, ⁶Michigan Medicine, VA Ann Arbor Healthcare System Center for Clinical Management Research, Ann Arbor, MI, ⁷Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA, ⁸Brigham and Women's, Boston, ⁹Salt Lake City VA Medical Center and University of Utah, Salt Lake City, ¹⁰University of Pennsylvania, Philadelphia, PA
Background/Purpose: Rheumatoid arthritis (RA) is a risk factor for osteoporosis and fractures yet the disease specific contributions to osteoporotic fractures (OFX) are not well understood.…
Abstract Number: 0101 • ACR Convergence 2020
Romosozumab After Denosumab Improves Lumbar Spine and Maintains Total Hip Bone Mineral Density in Postmenopausal Women with Low Bone Mass
Michael R McClung¹, Michael A Bolognese², Jacques P Brown³, Jean-Yves Reginster⁴, Bente Langdahl⁵, Norma Ruiz-Santiago⁶, Yifei Shi⁶, Maria Rojeski⁶, Jen Timoshanko⁷, Cesar Libanati⁷, Helina Kassahun⁶ and Mary Oates⁶, ¹Oregon Osteoporosis Center, Portland, OR, ²Bethesda Health Research Center, Bethesda, MD, ³Laval University and CHU de Québec (CHUL) Research Centre, Québec City, Canada, ⁴University of Liège, Liège, Belgium, ⁵Aarhus University Hospital, Aarhus, Denmark, ⁶Amgen Inc., Thousand Oaks, CA, ⁷UCB Pharma, Brussels, Belgium
Background/Purpose: Romosozumab, an anti-sclerostin antibody that increases bone formation while decreasing bone resorption, reduces fracture risk within 12 months. Here we evaluate the effects of…
Abstract Number: 0119 • ACR Convergence 2020
Fracture Liaison Service at an Academic Center with an Open Health System: 30-month Outcomes
Donna Jose¹, Micah Yu², Karina Torralba³, Christina Downey⁴, Justin Dunn⁵ and Vinicius Cabido⁵, ¹Loma Linda University Medical Center, Ontario, CA, ²Loma Linda University Medical Center, Loma Linda, CA, ³Loma Linda University School of Medicine, Redlands, CA, ⁴Loma Linda University Medical Center, Redlands, CA, ⁵Loma Linda University Medical Center, Loma Linda
Background/Purpose: Osteoporosis causes significant morbidity, mortality and healthcare burden. There continues to be a care gap in osteoporosis recognition, treatment and prevention. Several healthcare systems…
Abstract Number: 0544 • ACR Convergence 2020
Risk Factors for Lumbar Vertebral Osteoporosis Do Not Reflect Factors Traditionally Associated with Osteoporosis at the Hip
Marwan Bukhari¹ and Mrinalini Dey², ¹Rheumatology Department, University Hospitals of Morecambe Bay NHS Trust, Lancaster, United Kingdom, ²Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, United Kingdom
Background/Purpose: The most common site of osteoporotic fragility fractures is the thoracic spine. However, bone mineral density (BMD) measurements at the hip are used to…

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