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Abstracts tagged "osteoporosis"

  • Abstract Number: 1276 • ACR Convergence 2022

    Bone Density Imaging: Evaluation of Equipment and Process of Care Quality in US Veterans

    Karla Miller1, Melissa Steffen2, Kimberly McCoy2, Michelle Mengeling2, Heather Davila2, Shylo Wardyn2 and Samantha Solimeo2, 1University of Utah Division of Rheumatology/VA Salt Lake City Health Care, Salt Lake City, UT, 2Iowa City VAMC, Iowa City, IA

    Background/Purpose: Osteoporotic fractures contribute to significant morbidity and mortality. Dual-energy x-ray absorptiometry (DXA) is a valuable tool to identify osteoporosis, assess fracture risk, and monitor…
  • Abstract Number: 1320 • ACR Convergence 2022

    Performance of FRAX® Brazil and NOGG Methodology with and Without Bone Mineral Density upon Predicting Fractures on a Community-Dwelling Elderly Population with High Incidence of Osteoporotic Fractures: The São Paulo Ageing and Health (SPAH) Study

    Thiago Q Freitas1, Leonardo F G Olalla1, Liliam Takayama1, Valeria Caparbo2, camille figueiredo2, Luana Machado3, Diogo Domiciano4 and Rosa Pereira2, 1University of São Paulo, São Paulo, Brazil, 2Bone Metabolism Laboratory, Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 3Hospital das Clinicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 4Hospital das Clinicas, Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil

    Background/Purpose: SPAH is a prospective cohort of ≥65-year-old community-dwelling elderly with high fracture risk (40.3/1,000 person-years in women and 30.6/1,000 in men for vertebral fractures…
  • Abstract Number: 1277 • ACR Convergence 2022

    Improving Patient Appropriate Osteoporosis Screening with Dual Energy X-ray Absorptiometry Scans in an Academic Internal Medicine Practice

    Nithin Pusapati1, Rebecca Fitzpatrick1, Manya Gupta1 and Sonali Khandelwal2, 1Rush University Medical Center, Chicago, IL, 2Rush University, Chicago, IL

    Background/Purpose: Nearly 53.6 million people in America have osteoporosis with increasing incidence each year (Brauer, JAMA 2009). Almost 25% of people with a hip fracture…
  • Abstract Number: 1322 • ACR Convergence 2022

    Follow up of Incidentally Noted Vertebral Compression Fractures

    Jason Yang1, Alexia Hwang1, Megan Brochu2, Krista Sabina2, Meridith Malysz2, Bruce Weinstein3 and Jonathan Cheah1, 1UMass Chan Medical School, Worcester, MA, 2UMass Memorial Health, Worcester, MA, 3UMass Memorial Health, UMass Chan Medical School, Worcester, MA

    Background/Purpose: Vertebral compression fractures (VCFs) in general represent a clinical diagnosis of osteoporosis, predisposing to an increased risk of additional fractures. However, a significant number…
  • Abstract Number: 1304 • ACR Convergence 2022

    Glucocorticoids Affect Bone Mass and Strength by Inhibiting Osteoprogenitor Cell Maturation

    Thomas Ambrosi1, Mathew Murphy1, Charles KF Chan1 and Nancy Lane2, 1Stanford University, Stanford, CA, 2University of California Davis, Hillsborough, CA

    Background/Purpose: Glucocorticoid (GC) induced osteoporosis remains a significant health issue. While GCs are known to reduce bone formation and bone mass, patients treated with GCs…
  • Abstract Number: 1323 • ACR Convergence 2022

    Secondary Prevention of Vertebral Fractures Sustained Efficacy over Time

    JOSE ELOY OLLER RODRIGUEZ1, Elena Grau García2, Samuel Leal Rodriguez3, Laura Mas Sanchez2, Pablo Francisco Muñoz Martínez4, Carmen Riesco Bárcena5, Anderson Huaylla Quispe6, Cristobal Pavez Perales2, Francisco Miguel Ortiz Sanjuan7, José Ivorra Cortés2, Inés Cánovas Olmos2, Luis González Puig8, Isabel Martínez-Cordellat2, Carmen Nájera Herranz7, Rosa Negueroles Albuixech2, Elvira Vicens Bernabeu7, Alba Torrat Novés5, Daniel Ramos Castro2 and José andrés Román ivorra3, 1Hospital Universitario de La Fe, València, Spain, 2Rheumatology Department. Hospital Universitario y Politécnico La Fe, València, Spain, 3Hospital Universitari i Politécnic La Fe, València, Spain, 4Hospital Universitario y Politécnico La Fe, València, Spain, 5Rheumatology Department. Hospital Universitario y Politécnico La Fe, València, 6Medicina, València, Spain, 7Hospital Universitario de La Fe, València, 8Rheumatology Department. Hospital Universitario y Politécnico La Fe, Torrente, Valencia, Spain

    Background/Purpose: Vertebral fractures entail a notorious social and health problem, and their presence is the greatest risk factor for the appearance of a new vertebral…
  • Abstract Number: 1305 • ACR Convergence 2022

    Characterizing Bone Microarchitecture with MRI in Patients with Systemic Lupus Erythematosus

    Joshua Novack1, Gregory Chang2, Stephen Honig1, Anmol Monga2, Xiaoliu Zhang3, Punam Saha3, Dimitri Martel2, Peter Izmirly4, H Michael Belmont5, Jill Buyon4 and Amit Saxena5, 1NYU Langone Health Department of Medicine, New York, NY, 2NYU Langone Health Department of Radiology, New York, NY, 3University of Iowa Departments of Radiology and Electrical and Computer Engineering, Iowa City, IA, 4NYU Grossman School of Medicine, New York, NY, 5NYU School of Medicine, New York, NY

    Background/Purpose: Fractures in patients with systemic lupus erythematosus (SLE) are more common than age and sex matched controls. Fracture risk is traditionally assessed by dual-energy…
  • Abstract Number: 1325 • ACR Convergence 2022

    The Risks of Osteoporotic Fracture After Lung Transplant: A Retrospective Cohort Study at an International Transplant Center

    Adil Vural1, Sarah Keller2, Neel Tapryal3, Komal Mushtaq4, Hassan Shaheen1, Chao Zhang2, Marie Budev2, Abby Abelson2 and Chad Deal5, 1Cleveland Clinic, Westlake, OH, 2Cleveland Clinic, Cleveland, OH, 3Cleveland Clinic, Rocky River, OH, 4Cleveland Clinic, Fairview Park, OH, 5Cleveland Clinic, Shaker Heights, OH

    Background/Purpose: Osteoporotic fractures are a well-known complication of lung transplant (LT) and can significantly impact the quality of life of LT recipients. Although much is…
  • Abstract Number: 1146 • ACR Convergence 2021

    Study of Vertebral and Femur Fracture Prevalence and Scanographic Bone Attenuation Coefficient of the First Lumbar Vertebra in an Academic Hospital Setting

    Zareen Vaghaiwalla1, Paul Wasserman1 and Gurjit Kaeley2, 1University of Florida College of Medicine Jacksonville, Jacksonville, FL, 2University of Florida, Jacksonville, FL

    Background/Purpose: Patients with osteoporosis are prone to suffer fragility fractures leading to an increased risk of future fractures. Detection of osteoporosis has been led by…
  • Abstract Number: 1148 • ACR Convergence 2021

    Prevalence and Risk Factors of Insufficiency Fractures of the Foot and Ankle Joint in Rheumatic and Musculoskeletal Diseases

    Bjoern Buehring1, Nadine Al-Azem1, Ioana Andreica1, David Kiefer2, Uta Kiltz1, Styliani Tsiami1, Xenofon Baraliakos1 and Juergen Braun1, 1Rheumazentrum Ruhrgebiet Herne, Ruhr-Universität Bochum, Herne, Germany, 2Rheumazentrum Ruhrgebiet Herne, Ruhr-Universität Bochum, Essen, Germany

    Background/Purpose: Unlike fragility fractures, high-trauma and insufficiency fractures (IF) are not classically considered osteoporotic fractures. Patients with rheumatic and musculoskeletal diseases (RMD), especially those with…
  • Abstract Number: 1325 • ACR Convergence 2021

    Osteoporosis in Psoriatic Arthritis

    Sara M. Rojas Herrera1, Ignacio Braña Abascal1, Maria Priego Fernanddez-Martos1, Delia Fernandez Lozano1, Lara M. Chaves Chaparro1, Raul Veroz Gonzalez1, Juan J. Aznar Sanchez2 and Eugenio Chamizo Carmona1, 1Hospital de Mérida, Mérida, Spain, 2Hospital de Mérida, Merida, Spain

    Background/Purpose: Osteoporosis (OP) is a frequently underestimated comorbidity in immune-mediated inflammatory diseases (IMIDs). Its association with IMIDs is worse characterized in Psoriatic Arthritis (PsA) than…
  • Abstract Number: 0445 • ACR Convergence 2021

    Safety and Efficacy of Denosumab vs Risedronate in Patients with Glucocorticoid-Induced Osteoporosis and Rheumatoid Arthritis

    Jonathan Adachi1, Arkadi Chines2, Shuang Huang2, Kenneth Saag3, Willem Lems4 and Piet Geusens5, 1McMaster University/St. Joseph's Healthcare, Hamilton, ON, Canada, 2Amgen Inc., Thousand Oaks, CA, 3University of Alabama at Birmingham, Birmingham, AL, 4VUmc, Amsterdam, Netherlands, 5Maastricht University, Genk, Belgium

    Background/Purpose: Denosumab (DMAb) is approved for the treatment of glucocorticoid (GC)–induced osteoporosis (GiOP). In a phase 3, international, active-controlled, double-blind, double-dummy study, treatment with DMAb…
  • Abstract Number: 0446 • ACR Convergence 2021

    Clinical Characteristics, Including History of Myocardial Infarction and Stroke, Among US PMO Women Initiating Treatment with Romosozumab and Other Anti-osteoporosis Therapies

    Jay Lin1, Carrie Nielson1, Mary Oates1, Cynthia Deignan2 and Zhigang Yu1, 1Amgen Inc., Thousand Oaks, CA, 2Amgen, Inc., Agoura Hills, CA

    Background/Purpose: This study is an ongoing USFDA post-marketing requirement (2020-2024) to assess the impact of boxed warning on romosozumab (romo) treatment and the feasibility of…
  • Abstract Number: 0447 • ACR Convergence 2021

    Bone Anabolic Effects of a Novel Orally-Available Small Molecule SIK2/SIK3 Inhibitor

    Cheng-Chia Tang1, Shiv Verma1, Steve De Vos2, David Amantini3, Philippe Clement-Lacroix3, Nicolas Desroy3, Antonio Speziale4, Daniel Brooks5, Mary Bouxsein5, Janaina da Silva Martins1, Yingshe Zhao6, Henry Kronenberg1 and Marc Wein1, 1MGH Endocrine Unit, Boston, MA, 2Galapagos NV, Mechelen, Belgium, 3Galapagos SASU, Romainville, France, 4Galapagos GmbH, Basel, Switzerland, 5Beth Israel Deaconess Medical Center, Boston, MA, 6MGH Endocrine Unnit, Boston, MA

    Background/Purpose: Orally-available bone anabolic agents represent a major unmet medical need for patients with osteoporosis. Widespread use of parathyroid hormone (PTH)-based osteo-anabolic therapies is limited…
  • Abstract Number: 0448 • ACR Convergence 2021

    Bone Microarchitecture Assessed by 3D High-resolution Peripheral Quantitative Computed Tomography (HR-pQCT) as Predictor of Incident Fracture in Rheumatic Disease Patients on Long-term Glucocorticoid- a Five-year Longitudinal Study

    ho SO1, Xerox Lau1, Vivian Hung1, Steve Pang2, Shirley Ying3, Kitty Kwok4, Ka Lai Lee5, Jolly Lee6, Jack Lee1, James Griffith1, Ling Qin1 and Lai-Shan Tam7, 1The Chinese University of Hong Kong, Hong Kong, Hong Kong, 2Kwong Wah Hospital, Hong Kong, Hong Kong, 3Prince Margaret Hospital, Hong Kong, Hong Kong, 4Queen Elizabeth Hospital, Hong Kong, Hong Kong, 5Pamela Youde Nethersole Eastern Hospital, Hong Kong, Hong Kong, 6Tai Po Hospital, Hong Kong, Hong Kong, 7Department of Medicine & Therapeutics, The Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China (People's Republic)

    Background/Purpose: Impaired bone quality and strength estimated by high resolution peripheral quantitative computer tomography (HR-pQCT) in patients with rheumatic diseases on long-term glucocorticoid (LTGC) therapy…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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