ACR Meeting Abstracts

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Abstracts tagged "osteoporosis"

  • Abstract Number: 0121 • ACR Convergence 2020

    Association of Low Bone Density with Need for Early Revision After Elective Joint Replacement for Osteoarthritis in Postmenopausal Women

    Rashmi Dhital1, P. Daniel Nicholas2, Gregory Emkey3 and Anthony Donato2, 1Reading Hospital and Medical Center, West Reading, 2Reading Hospital and Medical Center, West Reading, PA, 3Reading Hospital and Medical Center, Reading, PA

    Background/Purpose: Total joint replacement (TJR) is the standard surgical treatment for end-stage hip and knee osteoarthritis (OA). Patient optimization may limit the need for early…
  • Abstract Number: 0926 • ACR Convergence 2020

    Risk Factors for Fractures and Osteoporosis Among Patients with Systemic Sclerosis in a United States Cohort

    Sina Famenini1, Jamie Perin2, Kristin Wipfler3, Kaleb Michaud4 and Zsuzsanna McMahan5, 1Johns Hopkins School of Medicine, Baltimore, MD, 2JHUSPH, Baltimore, 3FORWARD, The National Databank for Rheumatic Diseases, Omaha, NE, 4University of Nebraska Medical Center, Omaha, NE, 5Johns Hopkins University, Baltimore

    Background/Purpose:Systemic sclerosis (SSc) is associated with several risk factors for osteoporosis and fractures due to malabsorption or malnutrition, physical disability, chronic inflammation, and use of…
  • Abstract Number: 0104 • ACR Convergence 2020

    Bone Effects of One-year Tofacitinib Treatment in Rheumatoid Arthritis

    Attila Hamar1, Anita Pusztai2, Edit Végh1, Ágnes Horváth1, Katalin Gulyás1, Szilvia Szamosi1, Zsófia Pethő1, Nóra Bodnár1, Boglárka Soós1, Monika Czókolyová1, Sándor Szántó1, Gabriella Szűcs1, Harjit Bhattoa1, Gábor Nagy1, Gábor Tajti1, Andrea Domján1, Katalin Hodosi1 and Zoltán Szekanecz1, 1University of Debrecen, Debrecen, Hungary, 2University of Debrecen Faculty of Medicine, Department of Rheumatology, Debrecen, Hungary

    Background/Purpose: Oral JAK inhibitor, tofacitinib appeared as a new therapeutic option, beside biological therapies, which has already proven its safety and effectivity in RA, but…
  • Abstract Number: 0122 • ACR Convergence 2020

    Osteoporosis Medication Utilization Patterns over Time in the ACR RISE Registry

    Nitasha Khullar1, Lang Chen2, Jeffrey R Curtis3, Joshua Baker4, Huifeng Yun3, Andreas Reimold5 and Maria (Maio) Danila6, 1University of Alabama Birmingham, Birmingham, AL, 2University of Alabama at Birmingham, Birmingham, AL, 3Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 4University of Pennsylvania, Philadelphia, PA, 5Veterans Affairs North Texas Healthcare System / UT Southwestern Medical Center, Dallas, TX, 6University of Alabama at Birmingham (UAB), Birmingham, AL

    Background/Purpose: Many effective medications are available for osteoporosis treatment. However how rheumatologists use these therapies is not well understood, particularly in patients with concomitant rheumatologic…
  • Abstract Number: 0966 • ACR Convergence 2020

    Decoupling Inflammation and Bone Loss in Rheumatoid Arthritis via Schnurri-3

    Zheni Stavre1, JungMin Kim2, Jae-Hyuck Shim2 and Ellen Gravallese3, 1University of Massachusetts Medical School-Rheumatology Division, Worcester, MA, 2University of Massachusetts Medical School, Worcester, MA, 3Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Rheumatoid arthritis (RA) is a chronic inflammatory disease that leads to local and systemic bone loss. TNF is a key mediator of bone loss,…
  • Abstract Number: 0105 • ACR Convergence 2020

    Use of Peripheral Quantitative Computed Tomography in the Assessment of Bone Mineral Density in Anti-TNF-treated Rheumatoid Arthritis and Ankylosing Spondylitis Patients

    Balázs Juhász1, Katalin Gulyás1, Ágnes Horváth1, Edit Végh1, Anita Pusztai2, Ágnes Szentpétery3, Zsófia Pethő1, Nóra Bodnár1, Attila Hamar1, Levente Bodoki1, Harjit Bhattoa1, Éva Szekanecz1, Katalin Hodosi1, Andrea Domján1, Szilvia Szamosi1, Csaba Horváth4, Sándor Szántó1, Gabriella Szűcs1, Hennie Raterman5, Oliver FitzGerald6 and Zoltán Szekanecz1, 1University of Debrecen, Debrecen, Hungary, 2University of Debrecen Faculty of Medicine, Department of Rheumatology, Debrecen, Hungary, 3Uppsala University Hospital, Uppsala, Sweden, 4Semmelweis University, Budapest, Hungary, 5Northwest Clinics, Alkmaar, Netherlands, 6Conway Institute for Biomolecular Research, University College Dublin, Dublin, Ireland

    Background/Purpose: Rheumatoid arthritis (RA) and ankylosing spondylitis (AS) have both been associated with generalized and localized bone loss. Inflammatory cytokines like tumor necrosis factor (TNF)…
  • Abstract Number: 0123 • ACR Convergence 2020

    Aromatase Inhibitor-Associated Bone Loss: Screening and Prevention

    Matthew White1 and Luke Barre2, 1Roger Williams Medical Center, Providence, RI, 2Hawthorn Medical Associates, Dartmouth, MA

    Background/Purpose: Aromatase inhibitors (AI) are frequently used in hormone receptor-positive breast cancer, which encompasses nearly 75% of all breast cancers. By preventing peripheral estrogen production,…
  • Abstract Number: 1206 • ACR Convergence 2020

    Associations of Vascular and Bone Status in Anti-TNF-treated Rheumatoid Arthritis and Ankylosing Spondylitis Patients

    Anita Pusztai1, Attila Hamar2, Monika Czókolyová2, Katalin Gulyás2, Ágnes Horváth2, Edit Végh2, Zsófia Pethő2, Szilvia Szamosi2, Emese Balogh2, Nóra Bodnár2, Ágnes Szentpétery3, Harjit Bhattoa2, György Kerekes2, Balázs Juhász2, Éva Szekanecz2, Katalin Hodosi2, Andrea Domján2, Sándor Szántó2, Hennie Raterman4, Willem Lems5, Zoltán Szekanecz2 and Gabriella Szűcs2, 1University of Debrecen Faculty of Medicine, Department of Rheumatology, Debrecen, Hungary, 2University of Debrecen, Debrecen, Hungary, 3Uppsala University Hospital, Uppsala, Sweden, 4Northwest Clinics, Alkmaar, Netherlands, 5Amsterdam Rheumatology and Immunology Centre, Amsterdam, Netherlands

    Background/Purpose: Cardiovascular (CV) disease and osteoporosis (OP) have become increasing challenges in the ageing population, even more in patients with inflammatory rheumatic diseases, such as…
  • Abstract Number: 0106 • ACR Convergence 2020

    A Machine Learning-derived Radiomics Nomogram for Diagnosis of Osteoporosis and Osteopenia

    Qianrong Xie1, Yue Chen2, Yimei Hu3, Fanwei Zeng4, Pingxi Wang4, Lin Xu5, Jianhong Wu6, Jie Li1, Jing Zhu7, Ming Xiang8 and Fanxin Zeng9, 1Department of Clinical Research Center, Dazhou Central Hospital, Dazhou, China (People's Republic), 2Department of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, China (People's Republic), 3Department of Orthopedics, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China (People's Republic), 4Department of bone disease, Dazhou Central Hospital, Dazhou, China (People's Republic), 5Department of medical imaging, Dazhou Central Hospital, Dazhou, China (People's Republic), 6Department of Rheumatology, Dazhou Central Hospital, Dazhou, China (People's Republic), 7Department of Rheumatology and Immunology, Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, Chengdu, China (People's Republic), 8Department of Orthopedics, Sichuan Provincial Orthopedic Hospital, Chengdu, China (People's Republic), 9Department of Clinical Research Center, Dazhou Central Hospital, Dazhou, Sichuan, China (People's Republic)

    Background/Purpose: To discriminate osteoporosis and osteopenia using a quantitative computed tomography (QCT) radiomics signatures and clinical variables.Methods: This retrospective study enrolled 635 patients with QCT images and clinical characteristics from November…
  • Abstract Number: 0124 • ACR Convergence 2020

    Appropriate Timing of Denosumab Dosing and Subsequent Therapy After Discontinuation: An Academic Medical Center Experience

    Hugo Raposo1, Daniel Lindstrom1 and Jonathan Cheah2, 1University of Massachusetts Medical School, Worcester, MA, 2University of Massachusetts Medical School, Shrewsbury, MA

    Background/Purpose: Denosumab, a monoclonal antibody that binds to the receptor activator of nuclear factor kappa-B ligand (RANKL) is a popular choice for osteoporosis therapy. However,…
  • Abstract Number: 1336 • ACR Convergence 2020

    Bone Mineral Density, Trabecular Bone Score and Proximal Femur 3D-DXA Analysis in Psoriatic Diseases

    Eric Toussirot1, Renaud Winzenrieth2, Maxime Desmarets3, Daniel Wendling4, Francois Aubin5 and Gilles Dumoulin6, 1CIC biotherapies, Besançon University Hospital, Besançon, France, 2GALGO medical, Barcelona, Spain, 3INSERM CIC-1431, Besancon, France, 4CHU Besançon, department of rheumatology, Besancon, France, 5Dermatology, Besancon, France, 6Laboratoire de Biochimie Médicale, UF de Biochimie Endocrinienne et Métabolique, Besancon, France

    Background/Purpose: current data regarding areal bone mineral density (aBMD) in patients with psoriasis (PsO) or psoriatic arthritis (PsA) are conflicting. Results on Trabecular Bone Score…
  • Abstract Number: 0107 • ACR Convergence 2020

    Effects of Abaloparatide on Modeling and Remodeling Based Bone Formation

    David W Dempster1, Hua Zhou1, Sudhaker D Rao2, Chris Recknor3, Paul D Miller4, Benjamin Z Leder5, Miriam Annett6, Michael S Ominsky6 and Bruce H Mitlak6, 1Regional Bone Center, Helen Hayes Hospital, West Haverstraw, NY, West Haverstraw, NY, 2Bone & Mineral Research Laboratory, Henry Ford Health System, Detroit, MI, Detroit, MI, 3United Osteoporosis Centers, Gainesville, GA, Gainesville, GA, 4Colorado Center for Bone Research, Lakewood, CO, Lakewood, CO, 5Mass General Hospital, Harvard Medical School, Boston, MA, Boston, MA, 6Radius Health, Inc., Waltham, MA, Waltham, MA

    Background/Purpose: To evaluate abaloparatide-induced changes in the bone formation indices of mineralizing surface (MS), bone formation rate (BFR) and mineral apposition rate (MAR); and to…
  • Abstract Number: 0125 • ACR Convergence 2020

    A Resident-Led Interdisciplinary Quality Improvement Initiative to Increase Osteoporosis Screening in an Urban Clinic

    Catherine Teskin1 and Hiba Sayed2, 1Christiana Care, Wilmington, 2Christiana Care, wilmington, DE

    Background/Purpose: Osteoporosis is a major cause of morbidity and mortality in the United States. The USPSTF recommends screening all women age 65 and older or…
  • Abstract Number: 1337 • ACR Convergence 2020

    Relationship of the Pro12Ala Polymorphism of the PPARg Gene with Inflammatory Activity, Osteoporosis and Obesity in Patients with Psoriatic Arthritis

    Olga Compán1, Maria Elisa Acosta2, Sonia Pastor2, Guadalupe Manzano Canabal2, Luis Gomez-Lechon Quiros3, Cristina Hidalgo Calleja4, Noelia Cubino2, Ricardo Usategui5, Rogelio Gonzalez Sarmiento5, Olga Martinez Gonzalez6, Ana Isabel Turrión2, Javier Del Pino-Montes2 and Carlos Montilla Morales2, 1Hospital Universitario de Salamanca, ´Salamanca, Spain, 2Hospital Universitario de Salamanca, Salamanca, Spain, 3Complejo Asistencial Universitario de Salamanca, Salamanca, Spain, 4Hospital Universitario Salamanca, Salamanca, Spain, 5Instituto de Investigación Biomédica de Salamanca, Salamanca, Spain, 6Hospital Universitario de Salamanca, Zamora, Spain

    Background/Purpose: In the pathogenesis of psoriatic arthritis (PsA), increased inflammatory cytokines lead to increased RANGO-L activity and stimulation of osteoclasts, leading to osteoporosis. This comorbidity,…
  • Abstract Number: 0108 • ACR Convergence 2020

    The Relationship Between Body Fat Percentage and Bone Mineral Density in Rheumatoid Arthritis Patients

    Anastasia- Vasiliki Madenidou1 and Marwan Bukhari2, 1Rheumatology Department, University Hospitals of Morecambe Bay NHS Trust, Barrow-in-Furness, United Kingdom, 2Rheumatology Department, University Hospitals of Morecambe Bay NHS Trust, Lancaster, United Kingdom

    Background/Purpose: Currently, Dual-Energy X-ray Absorptiometry (DEXA) scans are used to determine fracture risk by calculating Bone Mineral Density (BMD). It is well established that body…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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