Abstracts tagged "Osteopontin and systemic lupus erythematosus (SLE)"

Abstract Number: 2702 • 2013 ACR/ARHP Annual Meeting
Molecular Pathogenesis and Genetics Of Tartrate-Resistant Acid Phosphatase Deficiency In Systemic Lupus Erythematosus
Jie An¹, Tracy A. Briggs², Audrey Dumax-vorzet², Alice Wiedeman³, Laurence Chaperot⁴, Joel Plumas⁴, Yanick J. Crow² and Keith B. Elkon⁵, ¹Division of Rheumatology, Department of Medicine & Immunology, University of Washington, Seattle, WA, ²Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom, ³Department of Immunology, University of Washington, Seattle, WA, ⁴Inserm U823/Ujf/EFS, Immunobiology & Immunotherapy of Cancers, La Tronche, France, ⁵Department of Medicine & Immunology, University of Washington, Seattle, WA
Background/Purpose: Biallelic mutations in ACP5, encodng tartrate-resistant acid phosphatase (TRAP), result in the immuno-osseous disorder spondyloenchondrodysplasia (SPENCD), characterized by a variety of autoimmune phenotypes –…

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Abstracts tagged "Osteopontin and systemic lupus erythematosus (SLE)"

Molecular Pathogenesis and Genetics Of Tartrate-Resistant Acid Phosphatase Deficiency In Systemic Lupus Erythematosus